<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08134

Description Mediator of RNA polymerase II transcription subunit 30
SequenceMAGQFPGGYQSPSGHRGNYNSPIIQQHLNQMNVPNQMGMMGFNQNNMMNSPQMQGVPGQGNQDMGLNPGMMQQNQQQQQPAQGMQPNPQQVPTNQHQPGANQMVGQNPMHQAAQPSPQMGMQQQQQQQQQQQQQQQQQQQQQSSNVGPGNPMNNPQSQNQSVPPNQPGAGTAVQQQQKAEFNLLSLCRIGQETVQDIVSRFQEVFGILRSIQPPNGTNQGQLSSNDKKAKVQEQFRTIRLLFKRLRLLYDKCNDNCQQGMEYTHVESLIPLKGELERTEPVHTEEYKKALQENRELVAMVQLKNKQLREIIDKIRLTIWEINTMLSMRRC
Length330
PositionHead
OrganismAnopheles melas
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.04
Grand average of hydropathy-1.050
Instability index60.03
Isoelectric point9.08
Molecular weight37458.76
Publications

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP08134
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     264.58|      49|      49|      51|      99|       1
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    1-   41 (41.50/ 6.69)	..MAGqFPGgyqspsghRGN....YN.SPIIQQ.......................................HLNQMNVPNQMGMMG
   51-   99 (103.16/27.84)	PQMQG.VPG........QGNQDMGLN.PGMMQQNQQQQQPA............................QGMQPNPQQVPTNQHQPG
  108-  149 (76.73/18.77)	PMHQA...A........QPSPQM.....GMQQQQQQQQQQQ............................QQQQQQQQQQSSN.VGPG
  155-  221 (43.20/ 7.27)	PQSQ...............NQSVPPNqPGAGTAVQQQQKAEfnllslcrigqetvqdivsrfqevfgilRSIQP.PN..GTNQGQ..
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP08134 with Med30 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MAGQFPGGYQSPSGHRGNYNSPIIQQHLNQMNVPNQMGMMGFNQNNMMNSPQMQGVPGQGNQDMGLNPGMMQQNQQQQQPAQGMQPNPQQVPTNQHQPGANQMVGQNPMHQAAQPSPQMGMQQQQQQQQQQQQQQQQQQQQQSSNVGPGNPMNNPQSQNQSVPPNQPGAGTAVQQQQ
1
177

Molecular Recognition Features

MoRF SequenceStartStop
NANANA