<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08131

Description Uncharacterized protein
SequenceMNMRPLKRPRLGPPDVYPQEAKQREDELTSTHVKHGFATEHKLSEEFGTARNCNVSASKVGAYFNAILAKKEELMTLPDSGRKKQQINPKDNFWPVTARNKTTLDTWFKDLAGTKPLSSLAKKAPSFNKKEEIFAMLCENQVTMQRAAWFIKLSSAYTVAVSEAKIKKRQMPDPATEWTGTMIKFMKDLIPKLHEHYHQGPLQEKPSSGAAGSSGGLGSGASGLGLSSGAGGTNAVTIPPPLSSPAGSMHSPAGGNPVVGGSMHAQQQQQQQQQQQQPISPQEEQRIAQKQWNYSTQLCKYMYEEGLLDKQEFLNWIIDLLEKMKSSPNADDGLLRIYLPLAMQYLYDLVQSERFCRRLAYAVSKKLAQLINQMAESHNINLSSPEPQDASGKQPSIEAPESKSEKQNDKPSKEGTAGTVAQPADTKPPKVNPYEMIFTEYLQCSHHRDVILQLSSILQVITLECPTALVWCGVGETRSSSVLSGSPLDHLPVAPSALPIPTRYEKSNEDIRRQLFEAEESIKVRSRHAESRWCIDKWQTAAGNASLKILATLDALDGHCFDRMDSNNSLDSLYSKIFPPFQVQPLKPAESASAAGGSGGSGTGNMPSGLAAVDGKDAATKQFEYNVEQDSSIVKILCEWAVSWQRWGEHRAMVVAWLLDKRQNEVLTALENDSYTNNLNNSDDKDSVLSGSGLNGGQPVFQHILMNFLDHDAPVLDEAGSPQNKSQFTNLVHLFSELIRHDVFSHDAYMCCLISRGDLLTGAGGMLSLDSQGICNAGLGTGPISNKPATSSSPNGGGGVEDDVLQTDFKAKLEDLDDSNVDDDLDKLLQHIKEDQQNSMDAPDSPKDPEHAAPSVTGLGKAESSSRHFLYTEHFPLCQDDPISQHDCNQRYILLYGVGKERDEKKHAVKKMSKEICKLFSKKFSIDVAEGGKVKKHSRSEFNFESTSNKCQAMSYFDQHVVTWQCAVQVQEMLNAFAIGNSNYLPVQEHVAFLFDLMESAFNIYGLIDTCIQILRELPEVELQLIGKSSMALVRSYTTSLSLYVVGVLRRYHCCLLLSQEQTTAIFEGLCRIVKHVSNPSDCSSAERCILAYLYDLYSACSSLKARPQQEPFHNAYPKIKQALYTPLQPTPSAHTYNPQFMLDIITNPRRGGKIESGWARQLNESASNRYSFVCNAVVAVTRDIDNDCLNDIAAMCAELTACCNSLSTEWLGVLIALCGSNRDAGYYVDVLTQVDVQNTNIHNALSVFTSILVARHCFSLENFVAHVALPSLVQACKGRGETTPEIEAGARLSCHLLLRLFKTIECPQPGLYSVSTSPNPITVGNAHNIKLSCDRHLLAAAHKNIGVAPVLAVLKGILVVGDATAHKVSSIFGTGKRSGLNTPVHPGSTPKSMAGSGDLSHILGTSDLSILGNPDESMLDVS
Length1423
PositionKinase
OrganismAnopheles melas
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.07
Grand average of hydropathy-0.351
Instability index50.97
Isoelectric point6.09
Molecular weight156041.92
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08131
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     171.83|      53|     165|     996|    1049|       3
---------------------------------------------------------------------------
  996- 1049 (83.87/74.58)	DLMESAFNIYGLI.DTCIQILRELPEVELQLIGkSSMALVRSYTTSLSLYVVGVL
 1162- 1215 (87.96/72.81)	QLNESASNRYSFVcNAVVAVTRDIDNDCLNDIA.AMCAELTACCNSLSTEWLGVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.89|      18|     165|     465|     482|       6
---------------------------------------------------------------------------
  465-  482 (34.81/22.21)	CPTALVWCGVGETRSSSV
  638-  655 (38.09/25.03)	CEWAVSWQRWGEHRAMVV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      83.00|      15|     165|     240|     257|       7
---------------------------------------------------------------------------
  241-  255 (32.35/17.11)	PLS.SPAGSMHSPAGG
  585-  597 (25.83/ 8.93)	PL..KPAESA.SAAGG
  783-  797 (24.83/ 8.07)	PISnKPATS.SSPNGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     211.30|      67|     173|    1062|    1132|       8
---------------------------------------------------------------------------
 1062- 1132 (111.85/88.96)	QTTAIFEGLcRIVKHVSNPSDCSSAERCIL.AYLYDLYSACsslKARPQQEPFHNAYPKIK....QALYTPLQ.PTP
 1238- 1310 (99.45/66.69)	QNTNIHNAL.SVFTSILVARHCFSLENFVAhVALPSLVQAC...KGRGETTPEIEAGARLSchllLRLFKTIEcPQP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08131 with Med12 domain of Kingdom Metazoa
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