<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08130

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMDNSKTTSKTTLLKLMLLRAWKERWTDCQWGINVKTILTRGVSGDVYNLADAIIQQAVVGSGANMLFLSYLKHSLCAHLISHAAVLNRIAKYDQFDKHHCLIALLDFLKSIIDGVTCRGKQEEAILTKATVSLVHWLLQIYECVLQSYAEDSTLQPEEEEVVQRVAVVLERIVENPFLLGVLSIGKCDDPELFIALQKRFNGISNLTLTTGYVANVGGGNANSLTVTDCMRKLVLLEVDALEMRPFDGGKVEPITYSLQPLIAIEVLLNPMCDTHQYVAQLINLKRLKGFTYARLYCELMRGCLIALNNVEGTAKESLLCAFAFIKVPHILHQLHAKTNGAEQQDEATGATYSVEVLEAFDLLLQDTPVLDYMDMKCACNVVECLLKEMVKLQLLTDTHVKQLVALREPVTAGLHKLDANSAPLTMMLKFVFRVESPLAGILKALSTDCSKVQDALLAMLCQVLTGNSLDLVLSVASVEGKFKAFISGLLKCNDYAKQATTAEIGKAPTTRSALFDVSFMILASIAQSYGSDVILAEGGNSFFEKWVRDYMVERKKTKSPMTMVKQADPMVLEELIMAMNNSEGMYVGLKASSLRWEDICYTIPALVHQVLMAWESESIAPLEIKKMLDGLKAYFSTFAVCAASWLCAYMQMVRQDEQLKPMNMVQQLCSALAGPLADEWQQQDYCKERFGLMGQIVRRMQQEFLRTPQVNPKLRALFPSQQQQHVVSHLPLEEQFEEAWKAIAERGWLPIETTFLLDTLLQSCGPAWLVEKLIGKLFVCKYVRDLNKTMDIIFAIMHLDIERCTIALLSQLVPMMLLSKAQTPEIVDPQSRVLAKLCVYCIIVTMETSLTATKKRTRGTASSELEDLDALCTSAKLRKIELEGMGVGCTESATGGATGTEFSLDSALEPTASAWTTEAASNASLKEPLQSCLQTLFRTFAQHIATDELSPKVYFVFQFLSLLVESGRERIMCVLKLLPNGLVQSLLKINATDEMTVGLILRVNI
Length1005
PositionTail
OrganismAnopheles melas
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.07
Grand average of hydropathy0.158
Instability index41.92
Isoelectric point5.73
Molecular weight111806.58
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08130
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     148.04|      51|     167|     224|     322|       1
---------------------------------------------------------------------------
  215-  273 (80.98/98.17)	NVGGGNANSltvtdcmrKL..VLLEVDALEMRPFDGGKVEPITYSLQPLIAIEVLLN..PMCD
  309-  371 (67.06/30.80)	NVEGTAKESllcafafiKVphILHQLHAKTNGAEQQDEATGATYSVEVLEAFDLLLQdtPVLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.75|      28|     166|     757|     826|       2
---------------------------------------------------------------------------
  522-  549 (49.47/16.16)	LASIAQSYGSDVILAE.GGNSFFEKWVRD
  757-  785 (47.28/101.25)	LDTLLQSCGPAWLVEKlIGKLFVCKYVRD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.53|      17|      98|     550|     566|       4
---------------------------------------------------------------------------
  550-  566 (31.58/21.79)	Y..MVERKKTKSPMTMVKQ
  649-  667 (27.95/18.46)	YmqMVRQDEQLKPMNMVQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.06|      21|     568|      18|      38|       6
---------------------------------------------------------------------------
   18-   38 (41.84/29.79)	LRAWKERWTDCQWGIN..VKTIL
  589-  611 (34.22/23.02)	LKASSLRWEDICYTIPalVHQVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.70|      27|     299|     613|     639|       8
---------------------------------------------------------------------------
  613-  639 (47.54/24.75)	AWESESIAPLEIKKMLDG.LKAYFSTFA
  914-  941 (42.16/21.29)	AWTTEAASNASLKEPLQScLQTLFRTFA
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08130 with Med24 domain of Kingdom Metazoa
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