<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08088

Description Mediator of RNA polymerase II transcription subunit 29
SequenceMMNQMGMMMQQQGVGVPGGPGGVGGVGMPGPGGVGVSPGMMQSPQMQQAQQQQVQQQQVQQQQQQQQVQQQQVQQQAQQQQQQHNQSAQQQAQQTEKVDNISKVKVLVGPLRDALSTTIKTAAQLIQQNTLADAGSKTVDLNNAPRFDKHLEEFYSICDQIELNLKTAKLCMQQCTSSQQYLPIPVATSQPPLTETNALTYNQYLEVVKLQIGYAKDIHDTLICAAQNISPSE
Length233
PositionTail
OrganismAnopheles funestus (African malaria mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.03
Grand average of hydropathy-0.618
Instability index64.68
Isoelectric point5.56
Molecular weight25514.50
Publications
PubMed=21129198
PubMed=31157884

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08088
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.11|      17|      17|      47|      63|       1
---------------------------------------------------------------------------
   47-   63 (34.19/ 8.65)	QQAQQQQVQQQQVQQQQ
   66-   82 (32.92/ 8.10)	QQVQQQQVQQQAQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.02|      14|      17|      13|      28|       2
---------------------------------------------------------------------------
   13-   28 (23.42/15.17)	GVGVpgGPGGVGGVGM
   33-   46 (28.60/12.32)	GVGV..SPGMMQSPQM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.42|      22|     101|     104|     126|       3
---------------------------------------------------------------------------
  104-  126 (31.88/31.89)	VKVLVGPLRDALSTTIkTAAQLI
  208-  229 (39.55/33.62)	VKLQIGYAKDIHDTLI.CAAQNI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08088 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MMNQMGMMMQQQGVGVPGGPGGVGGVGMPGPGGVGVSPGMMQSPQMQQAQQQQVQQQQVQQ
2) QQQVQQQQVQQQAQQQQQQHNQSAQQQAQQT
1
65
61
95










Molecular Recognition Features






MoRF SequenceStartStop




NANANA