<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08081

Description Uncharacterized protein
SequenceMPKILDSDIDSPIANLIKRSGTATTTTNNSSSSSSKQSAHYSNDTTSEKSDGPFEALVGRHHIVSGGGGNSNSSSSFFSSAYDAKDGSNEGGSSFGSGGAAIAVASGMGVVGPTVPLTQPQPPPPPPQPGQSAFFQSTVSHHHQPHHRGHRSDGADSGKGTGNAPANAPESRVKKYRHQQFSKNIYIGTKNAEKWDTLRNVLLFKNDVEFVSFLLKLAESNCWKKDSPLLNGFHSETLPAKSQGATSKGTRTKTGARGKQQLQEPQHEEDQQLEQQPQQQQLHSSSISYGSSKSTGSMGKKTKKVQFNKNVNIIHKLDNRRSGKMVSFSEKTLADEPSNLSHHDEDSTAIPEEDDGGGGGGGGGGAIGEDDDDEDEEEDMEEDDEDEEDEEEEEEEDEEEDEDQGEDKEAMAGKVDDGMLESDAVRKVDGFLSDSKEQDSNVVNHDPYLLDDLVKKTMRKTHPSTTNQPQQSNEVQQDSISSTMGSVSEDSLNTETEVLDYRIAEKIKTELEEKQKLERKTHNAEELPTTSNFFEQCEFDPSSVDEKPTMPHVKKGSVLERSRSGTVLDQPAYGGGPRKRGRRANHAADSGNVDLHIEYEEQEYRPLPGTRSTDGGPIEKSNFTSQAKQLQLQHAPATQRKTKGAGSTKNKVCTGCNIKHGADLCPLNAPLRAISNKIELNQWLEQNEDLIKKHKLFLKPAGNGEDMDDDMDEHYDDDEEDEDDDMDEEDDDGGDGSRANGKLELSPSFSEVSVPPEFELRLCPQSSANNAISSTTQNEAVQQQQEQHAKLNQLQDAPLQQAPVHEQQDQDSLMESKDSLPPPPPPPLAPPSSSSSSSFAGTIGMERESTPKSRTVSGHGLSIYTITFIAKYTKIGPLTGQIVRETEIQDDCTMRHIFETFDGVKSTYTSTENKNFSNWLRYIRPARNREQKNCVLQVHDGSIYFVTSKDLEPGTELLYWSNDSNSAWGKKKMEKTNCGGCNLKFDHPFYYRTHCSVFHDPGFSLTIRKYHCKVCGAAVLGKENIMKHAEKLHDGKGAYQCQFCQKFFLRLNYLEMHRTYGCSANPQRTRPLCDFCGRKFCQPQKLKVHIKRMHSDMADVLRDFQCKLCSKLLGSRAALQRHSKEVHSRNSAVVSCPRCQKLFQNRSNLKIHMLTHSGVRPFKCAENECTAAFTTKQCLQFHYKKVHGYTQEQMPKIERSVAYTFDAYSGGLNDGIIDEVQRRQRHKSSASEEGGYPTEKVERKKRSRHLNHFDETSLQQQQHQSQLQTQLQQADLSQGLQQESSDPTKVTSQQHLQQQSPQHPQLDYPNTPPAPQRLSTHPSTAQQHQLVLPNADVLQKDGELHQQKMLRQQQQQQQQQQQQLSIQQTADEQQDTVDQATGSQMQHHQHELHSDPQHSALDDQVMAKADQEEQTMHHHHHHHHQQLSRLPSPFSNNLLKTKNILESFNDLCRNESNLSLLSTKITSILNNNLKDIAKVAAIGTSGGSNGGSVEDIRKNIIDHQGHLDESRSDRLEDMQHLVHPLPDEQSKANSLNVSQLHRLNISNQLDTGSGSALQYKTNSDDDMKNVNEVDSNFVDMASLASNLKYKEYINGGGNAGLVISKGSKKWISDADQLPGGDGQQGESGVMLSTVTGRDFLTKLIMNGNVNTPPPNVADDEEEDDDNSTILDVVDSNNQNQQSSHSQIQQYTSNFTGLNLPDLPSFQSHAFQGHFNHQTLLGSFYNNTGTSAGRNTINTIPTSASMLVEAALNSVSNIITEAEISTNNNQNQGLNINHIDPGSGTDTASNNVSTNSFNASNIDESVDDMKLLKSHHFSMQLNSISQYSAQSTNDSGILSIRGAGSATVSRPKSREKIAIYEDSEMLNYENQHLSQQLQGTPHKLTSSVDSVRSALSPEQTGDFSYAATPSTSSRQHIVGGSPVRSSSRQIYAEHDLISPASTPSLPRYDFGPTDSNYSSARRQDAKTISSLTLESFESNLKDTHHMQQLSSDEDNSIVIAENLSVNAVSTEEKLKLSNASAAAATNSASSAGSSATEFIQHQKYGETGRTIGGSNLPATADMRIKYGNDELVDFQRNSIGDASDFQGLDMSSRSSVSAYHHSNFQLSTQASSNLHFNRYHHHIYDILSEREQQQQQPQQQQQQQQQQQQQQQQQQQSQQHHHQQQQQQQQQQGQQHHQHQHQHHHHQHQTQQQQQQQQQQQQQQSQQHTQQQQQQDSFQLEQTQLQHLVQEHVQSQDSDADQSVTVDLSRSSSYLVQSPPTPAISYSSHHHPDMIRMVSLDLSSNTGSHHSVNNGSHHAVRHASFISSQIQPAEHHRLLAGDQLSASNHRLLVSDPATHLIFEQNNRLLSDATGQPAPPPPPPPRHVVSPTRGFGAYHHHHHHHHHHQVSSTNYHHSMKQNIASPPINQHSSTAAAYHPFPTYY
Length2423
PositionKinase
OrganismAnopheles funestus (African malaria mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.05
Grand average of hydropathy-0.985
Instability index59.06
Isoelectric point5.79
Molecular weight269377.62
Publications
PubMed=21129198
PubMed=31157884

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08081
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     207.20|      17|      17|    2146|    2162|       1
---------------------------------------------------------------------------
 1356- 1372 (24.66/ 6.64)	QQQQQQQQL.SIQQTADE
 1410- 1425 (27.19/ 8.21)	DQEEQTMHH..HHHHHHQ
 2134- 2150 (36.03/13.71)	QQPQQQQQQ.QQQQQQQQ
 2151- 2164 (26.77/ 7.95)	QQQQQSQQH.HHQQQ...
 2170- 2186 (36.94/14.28)	QQGQQHHQH.QHQHHHHQ
 2187- 2198 (24.95/ 6.82)	HQTQQQQ......QQQQQ
 2199- 2216 (30.66/10.37)	QQQQQSQQHtQQQQQQDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      84.36|      15|      15|     372|     386|       2
---------------------------------------------------------------------------
  372-  386 (32.30/18.47)	DDE.DEEEDMEEDDED
  389-  403 (26.73/13.97)	DEE.EEEEEDEEEDED
  717-  732 (25.33/12.85)	DDEeDEDDDMDEEDDD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     264.01|      33|      33|    1091|    1123|       3
---------------------------------------------------------------------------
 1007- 1035 (43.01/26.76)	IRKYHC..KVCGAAVLGKENIM....KHAEKLH........DG
 1036- 1068 (52.18/34.32)	KGAYQC..QFCQKFFLRLNYLE....MHRTYGCS....ANPQR
 1069- 1100 (53.89/35.73)	TRPL.C..DFCGRKFCQPQKLK....VHIKRMHS....DMADV
 1101- 1133 (49.14/31.81)	LRDFQC..KLCSKLLGSRAALQ....RHSKEVHS....RNSAV
 1134- 1157 (19.78/ 7.60)	V...SC..PRCQKLFQNRSNLKihmlTHS..............
 1159- 1197 (46.01/29.23)	VRPFKCaeNECTAAFTTKQCLQ....FHYKKVHGytqeQMPKI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     119.04|      32|      33|    1263|    1295|       4
---------------------------------------------------------------------------
 1281- 1314 (53.73/22.36)	QQESSDPTKVTSQQH...lqQQ.....SPQH..PQL.DYPNTPPA
 1316- 1353 (33.54/ 8.09)	QRLSTHPS..TAQQHqlvlpNA.....DVLQkdGELhQQKMLRQQ
 1373- 1402 (31.76/ 9.27)	QQDTVDQATGSQMQH.....HQhelhsDPQH..SAL.D.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.73|      11|      19|    2364|    2378|       5
---------------------------------------------------------------------------
 2364- 2378 (17.75/20.91)	RHVVSPTrgfgAYHH
 2385- 2395 (23.98/13.44)	HHQVSST....NYHH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      86.71|      19|      19|    2082|    2100|       6
---------------------------------------------------------------------------
 2076- 2092 (28.53/14.41)	NSIG..DASDFQ.GLDMSSR
 2093- 2112 (27.84/13.86)	SSVSAYHHSNFQlSTQASSN
 2113- 2129 (30.34/15.86)	LHFNRYHHHIYD.IL..SER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     463.50|     120|    2233|       6|     129|       7
---------------------------------------------------------------------------
    6-  129 (189.53/114.91)	DSDIDSPIANLIKRSGTATTTTNNSSSSSskQSAHYSNDTTSEKSDGpFEALVGRHHIVSGGGGNSNSSSSFFSSAYD.AKDGSNEGGS.SFGSGGAAIAV...ASGMGVVGPTVPL.....TQPQPPPPPPqP
 1583- 1654 (82.23/38.57)	................................................LASNLKYKEYINGGGNAGLVISKGSKKWIS.DAD.QLPGGDgQQGESGVMLST...VTGRDFLTKLIMN.....GNVNTPPP....
 2236- 2363 (191.74/103.74)	DSDADQSVTVDLSRSSSYLVQSPPTPAIS..YSSHHHPDMIRMVSLD.LSSNTGSHHSVNNGSHHAVRHASFISSQIQpAEHHRLLAGD.QLSASNHRLLVsdpATHL.IFEQNNRLlsdatGQPAPPPPPP.P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     106.72|      28|      33|    1881|    1909|       9
---------------------------------------------------------------------------
 1814- 1833 (25.93/ 7.17)	HHFSMQLNSI.SQ...YSAQSTND........
 1881- 1908 (48.87/23.02)	HKLTSSVDSVRSA...LSPEQTGDF.SYAATP
 1915- 1942 (31.92/11.54)	HIVGGS..PVRSSsrqIYAEH..DLiSPASTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     102.94|      25|      32|    1529|    1553|      10
---------------------------------------------------------------------------
 1487- 1511 (30.04/14.94)	GSNGGS...VEDIRKNIIDHQghLDESR
 1529- 1553 (40.15/22.52)	QSKANS.LNVSQLHRLNISNQ..LDTGS
 1558- 1582 (32.76/16.98)	QYKTNSdDDMKNVNEVD.SNF..VDMAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.73|      20|      21|     783|     803|      12
---------------------------------------------------------------------------
  783-  803 (31.38/21.49)	QQQEQHAkLNQLQDA.PLQQAP
  806-  826 (34.35/18.99)	EQQDQDS.LMESKDSlPPPPPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      69.30|      16|      21|    1210|    1226|      13
---------------------------------------------------------------------------
 1210- 1226 (25.18/20.90)	GGLNDGiIDEVQ.RRQRH
 1234- 1247 (22.18/12.19)	GGYP.T..EKVE.RKKRS
 1248- 1263 (21.95/11.97)	RHLNH..FDETSlQQQQH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.18|      20|      21|    1683|    1702|      14
---------------------------------------------------------------------------
 1668- 1694 (26.99/14.51)	TILDVVDsnnqnqqSSHSQIQQYTSNF
 1695- 1714 (36.18/22.78)	TGLNLPD.......LPSFQSHAFQGHF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     158.79|      47|      97|     134|     180|      16
---------------------------------------------------------------------------
  134-  180 (85.10/35.37)	FFQSTVSHHHQ.PHHRGHRSDGADSGKGTGNAPANAPESRVKKYRHQQ
  233-  280 (73.70/29.69)	FHSETLPAKSQgATSKGTRTKTGARGKQQLQEPQHEEDQQLEQQPQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.82|      21|      25|     589|     611|      19
---------------------------------------------------------------------------
  589-  611 (29.24/25.59)	DSGNVDlHIEYEEQEyRPL.....PGTR
  614-  639 (30.58/16.38)	DGGPIE.KSNFTSQA.KQLqlqhaPATQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.37|      14|      15|     421|     434|      21
---------------------------------------------------------------------------
  421-  434 (23.75/13.96)	ESDA.VRKVDGFLSD
  437-  451 (20.62/11.03)	EQDSnVVNHDPYLLD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08081 with Med12 domain of Kingdom Metazoa
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