<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08053

Description Uncharacterized protein
SequenceSASIAAQYALSFHLTVARTRSPYRIGVRLASSRSRRARVYVCVCGNSSVTMHTERRHRHRGARGTVTGHQTTGGTVIAATGTTAATATITTATQQPAIHPTVWEILSAELILSVAFLVRFLFTPPSVANEPEGTPELPAANRALFLEKVRQSNTACQNGDFSTAVQLYTDALGLDPGNHILYSNRSAARLKQGQFALALQDATRARELYPQWPKAYFRQGVALQCLGRYGEALAAFSAGLAQDPNSKQLLAGLVEASIKSPLRHALEPTFQQLKAMKLDQSPFVVISVVGQELLGAGQYHAAVTVLESALRIGSCSLKLRGSVFSALSSAHWALNQLDKAIAYMQQDLAVAKSLGDTAGECRAHGNLGSAYFSQGSYKEALTSHRYQLVLAMKCKDTQAAAAALTSLGHVYTAIGDYPNALASHKQCVQLVKQMGDRLQEAREIGNVGAVYLAMGEFDSAVDCHTQHLRLARKLGNQVEEARAYSNLGSSYHYKRNFTQAITYHESVLRIAQQLGDRAIEARAYAGLGHAARCGHDFVQAKRWHEKQLEMALAARDKVGEGRACSNLGIVYQLLGEHDAALKLHQAHLTIARQLQDKAGMGRAYGNIGNAYSAAGYYESAIKYHKQELIISKEVHDRSAEASTHGNLAVAYQALGAHDMALMHYRAHLNIARELKDTAGEACALLNLGNCLSSRQEFAQAVPYYEQYLMLSQELGDVAAEGKACHFLGYAHYCIGNYREAVRYYDQDLALAKDLQNKMNMGRAYCNLGLAHLALGNTGGALECQKYFLAIAHMTNHLPGKFRALGNIGDVLIRMGDVDEAIKMYQRQLALARQTRERGMEAAACGALGLAHRLLKKLDKALGYHTQELTLRQEMSDLPGECRAHGHLGAVHMALGNYTHAVKCYQEQLERAQELQDSAVEAQAFGNLGIARLNMGHYEDAIGYLEQQLGTLEQVNTATAQHDRARALGHLGDCYDALGDYHAEAIKCHERHLQLAIALQSARDQERAYRGLGNCYKSVGNLQEALVCLEKRLVVSHELGNAEAKAAAYGDLGGIHSALGNYEQAINCLEHQRDIARELGDRVLTSDAISGLGAVFHQMGDYDESLRLHKQDLELGESVSHATLQARACGNLGSVYDALRNYAESARYYEKQLTLTADRQTKAHACLALGRVYHSMEQVPQAIGFLRQGLAIAQSLNKLEDEAKLRYRLGLALVASGDDDAARQQMESAAQILESIRSDQVTPEARTQLYELQTACYQTLQRVLVGLGRTEEALVAAERCRSRMGADSNQSAENSLNNRKTLLTCSEYIFDTVNRSKTSIIYYSLAGADLYAWFLQPQKRIVRFHATKLDDQTLPMMKKKALMAPGHGGTTTGGGALALDKKGPTATGEAGGLVEQQSLLEQYINYVRDCLGVNSGSVLQEGDGSGWKSSNENLIDDFANERAGFLRMVNRNHLLNSSNYSLSSLFSLGSVGGSVASLQGSTRSIGSLQGSTRSRRSNMLPPWQGPSCLHVLYNLLLAPFEDLLPDISTTARIGRRELILVLEKELYLVPFAILRSGDEDGEYLSERCSLLTVPSLHTLRQKSRIKTREPAEGLNSALVIGGPKIPSSLSDTWGWSDSPASLQEAAMVSDMLNTKPLVSCSATKEAIVSELPAAECVHFAANVSWKLGAVVLSPGEVLDSQSQKRFYPNAAGELMGGDNDEETNDLSTANMEIPPLSDFILSAADLLSMKLSAKLVVLSSYHSVEPITGSGVANLAGSWLFAGTGAVLVSLWPVPETAAKILLRAFYSALLQGTRAARALAEAMQTVQHTKHFAHPANWAGFILIGGNVRLSNKVALIGQALCELMRTPDKCRDALRVCLHLVEKSLQRIHRGQKNAMYTTQKSIDNKAGPVSGWKDLLMAVGFRFEPAANGIPSSVFFPQSDPEDRLSQCSASLQALLGLSPTTLHALSKLVHGAEIADEIIGVMRNVVAQFPSKATDNESAIDVPLSVRLWRVSGCHELLASLGFDLMEVGQDQVTLRTGKQANRRNCQFVLQALLALFDTQEAPKSLGIESSSSSESLNEEESGEEQQQQQQQQAIQQNQSQQPTQQQQQQQQQQQQQSSQQAQQVQQQQQQQQMKGTSSGVSPTPTNADSQQRSISPAVTVKSQASYNFSRPPLPLRRVPFLSTRSAFISYVRRRGEPDGGQTDTAQSATNGGVSAIPNGNVLDTSLANTTDSELSDGYTTQQILLKSDHLAKGLGYSSLRGTIKVSRPGGGGESDAAFTPSPPVTIQNVDQNVSLALAHQTRIKNLYTNNGSLHGVTGTMNGAHGSTAPSYSLQDTLRDGVHHHPNPSHHRRPDSSSSASSATDWEGSGHATVLRRAAHQGHHLPPLPPPRQTLPMVESLRPLAPLAPVYNNINGTVVPTGAGGGKASIPNGGQKSLSVLESTSSDSEFERSFDLPGGSSSNAASISSKLTSLAHSLQSMRTRNKLKLGPQPHGQHSQQHQQQQHGQAQQQQQQQQQPQHGHMQHPLASTTMARTKLPVDQFGFLDRLSCRTEISSSASLANHIPPPRKPLSTLPDDERTLNLNANKLYFSPTDAEMLPLAEASPSDLGLGGKSHAPTMGPPMVGASGGVTGTSGKDGSGKSNQKTIQDSILRHMSREMTPTISEVYHERNIGLGLAPSLSKLLLSKNYDESAELGAKGGGSSVASVVAASAAAAAAAAAASMLNKPSAALTVGNLAEAMNEIEMNATTSSKLEEGACGICHSPSDLLCGCSATSTVAAVAAMTAALGANTMAKKSNSNKPWLSNVSPNIVKASDLTTADILEQQKQLKSSVSSGLTSNLSSSTENSLSTVVKRSGSPFSDLSRRDEGDGRSVADSQCSGSFRTDITGSTVTTSKSQQQVTSSQQQQQQQQQQQQQHQSSKQPPVQQQQQVVAAGGDQTGPASQPSVTMTTSTTVTQLRGKYIIDT
Length2950
PositionTail
OrganismAnopheles farauti
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.05
Grand average of hydropathy-0.342
Instability index48.05
Isoelectric point7.77
Molecular weight317972.97
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08053
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     152.03|      17|      17|    2079|    2095|       1
---------------------------------------------------------------------------
 2075- 2094 (32.32/13.60)	QqaiQQNQSQ.QPTQQ.QQQQ.....Q
 2095- 2113 (26.56/ 9.75)	Q..qQQQQSS.QQAQQvQQQQ.....Q
 2485- 2500 (33.25/14.22)	Q...QQ.QHG.QAQQQ.QQQQ.....Q
 2881- 2897 (34.37/14.97)	Q...QQVTSS.QQQQQ.QQQQ.....Q
 2898- 2920 (25.53/ 9.06)	Q...QQHQSSkQPPVQ.QQQQvvaagG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            21|    1013.80|      38|      39|     468|     505|       2
---------------------------------------------------------------------------
  348-  387 (51.66/23.62)	LA.VAKSLGDTAGECRAHGNLGSAYFSQGSY.KEAL.TSHryQ
  388-  425 (43.42/18.67)	LV.LAMKCKDTQAAAAALTSLGHVYTAIGDY.PNAL.ASH..K
  428-  465 (46.47/20.50)	VQ.LVKQMGDRLQEAREIGNVGAVYLAMGEF.DSAV.DCH..T
  468-  505 (54.55/25.35)	LR.LARKLGNQVEEARAYSNLGSSYHYKRNF.TQAI.TYH..E
  508-  545 (52.35/24.03)	LR.IAQQLGDRAIEARAYAGLGHAARCGHDF.VQAK.RWH..E
  548-  585 (50.76/23.08)	LE.MALAARDKVGEGRACSNLGIVYQLLGEH.DAAL.KLH..Q
  588-  625 (59.39/28.26)	LT.IARQLQDKAGMGRAYGNIGNAYSAAGYY.ESAI.KYH..K
  628-  665 (42.25/17.98)	LI.ISKEVHDRSAEASTHGNLAVAYQALGAH.DMAL.MHY..R
  668-  705 (49.62/22.40)	LN.IARELKDTAGEACALLNLGNCLSSRQEF.AQAV.PYY..E
  708-  745 (52.85/24.34)	LM.LSQELGDVAAEGKACHFLGYAHYCIGNY.REAV.RYY..D
  748-  785 (49.22/22.15)	LA.LAKDLQNKMNMGRAYCNLGLAHLALGNT.GGAL.ECQ..K
  788-  825 (45.83/20.12)	LA.IAHMTNHLPGKFRALGNIGDVLIRMGDV.DEAI.KMY..Q
  828-  865 (46.00/20.22)	LA.LARQTRERGMEAAACGALGLAHRLLKKL.DKAL.GYH..T
  868-  906 (52.32/24.02)	LT.LRQEMSDLPGECRAHGHLGAVHMALGNY.THAVkCYQ..E
  908-  945 (49.97/22.60)	LE.RAQELQDSAVEAQAFGNLGIARLNMGHY.EDAI.GYL..E
  951-  989 (44.81/19.51)	LE.QVNTATAQHDRARALGHLGDCYDALGDYhAEAI.KCH..E
  992- 1029 (43.75/18.87)	LQ.LAIALQSARDQERAYRGLGNCYKSVGNL.QEAL.VCL..E
 1032- 1069 (49.97/22.61)	LV.VSHELGNAEAKAAAYGDLGGIHSALGNY.EQAI.NCL..E
 1071- 1109 (41.24/17.37)	QRdIARELGDRVLTSDAISGLGAVFHQMGDY.DESL.RLH..K
 1112- 1149 (49.05/22.05)	LE.LGESVSHATLQARACGNLGSVYDALRNY.AESA.RYY..E
 1152- 1186 (38.32/15.61)	LT.LT...ADRQTKAHACLALGRVYHSMEQV.PQAI.GFL..R
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.89|      20|      22|    2576|    2597|       3
---------------------------------------------------------------------------
 2576- 2597 (31.27/26.82)	PTDAEmlPLAEASPSDLGLGGK
 2601- 2620 (38.62/25.67)	PTMGP..PMVGASGGVTGTSGK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.75|      20|      22|    2297|    2316|       4
---------------------------------------------------------------------------
 2297- 2316 (37.06/22.51)	LH.GVTGTMNGAHGSTAPSYS
 2321- 2341 (35.68/21.34)	LRdGVHHHPNPSHHRRPDSSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.39|      20|      21|    2822|    2841|       5
---------------------------------------------------------------------------
 2822- 2841 (32.46/18.46)	SNLSSSTENSLSTVV..KRSGS
 2844- 2865 (30.93/17.20)	SDLSRRDEGDGRSVAdsQCSGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.73|      19|      22|     231|     251|       6
---------------------------------------------------------------------------
  231-  251 (27.20/19.00)	EalAAFSAGL..AQDPNSKQLLA
  255-  275 (27.53/13.28)	E..ASIKSPLrhALEPTFQQLKA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.15|      11|      15|    1466|    1476|       7
---------------------------------------------------------------------------
 1466- 1476 (19.25/ 8.96)	SLGSVGGSVAS
 1483- 1493 (19.89/ 9.54)	SIGSLQGSTRS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     235.39|      73|     428|    1937|    2072|       8
---------------------------------------------------------------------------
 1232- 1293 (76.43/24.97)	..............LESIRS...DQVTpeARTQLYELQ.TACYQTLQrVLVGLGRTEEA..LVAAERCRSRMGADSNQSAEN
 1891- 1935 (43.81/105.09)	VSGWKDLLMAVGFRFEPAANgipSSVF..FPQSDPEDRlSQCSASLQ...................................
 1994- 2068 (115.16/65.65)	VSGCHELLASLGFDLMEVGQ...DQVT..LRTGKQANR.RNCQFVLQ.ALLALFDTQEApkSLGIESSSSSESLNEEESGEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.29|      15|      15|    2708|    2722|       9
---------------------------------------------------------------------------
 2708- 2722 (23.64/14.22)	LNK.PSAALTVGNLAE
 2724- 2739 (18.65/ 9.28)	MNEiEMNATTSSKLEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     279.89|      59|     211|    2155|    2220|      10
---------------------------------------------------------------------------
 1353- 1398 (50.66/28.13)	LPM...MKKKALMAPGHGGTTTGGGALAldkkgPTATGEA.....GGLVEQQSL..........
 1400- 1439 (48.97/26.78)	.......EQYINYVRDCLGVNSG..SVL.....QEGDGSGWKS.SNENLID.DFAN........
 2162- 2220 (95.43/60.87)	VPFLSTRSAFISYVRRRGEPDGGQTDTA.....QSATNGGVSAIPNGNVLDTSLANTTDSELSD
 2378- 2430 (84.83/52.37)	LPMVESLRPLAPLAPVYNNING...TVV.....PTGAGGGKASIPNGG..QKSL.SVLESTSSD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.79|      13|      15|    2637|    2649|      11
---------------------------------------------------------------------------
 2637- 2649 (23.61/15.21)	RHMSREMTPTISE
 2654- 2666 (20.18/11.72)	RNIGLGLAPSLSK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.61|      11|      15|    2453|    2463|      12
---------------------------------------------------------------------------
 2453- 2463 (17.67/ 9.17)	KLTSLAHSLQS
 2471- 2481 (21.94/13.76)	KLGPQPHGQHS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.18|      25|      31|     152|     176|      15
---------------------------------------------------------------------------
  152-  176 (44.96/28.12)	SNTACQNGDFSTAVQLYTDALGLDP
  186-  210 (42.22/25.90)	SAARLKQGQFALALQDATRARELYP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.88|      27|     417|    1301|    1334|      18
---------------------------------------------------------------------------
 1301- 1334 (32.39/42.81)	LLTCSEYifDTVNRSKTSIIyYSLAGadlyAWFL
 1734- 1760 (46.49/30.12)	LVVLSSY..HSVEPITGSGV.ANLAG....SWLF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08053 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AFISYVRRRGEPDGGQTDTAQSATNGGVSAIPNGNVLDTSLANTTDSELSDGYTTQ
2) LYTNNGSLHGVTGTMNGAHGSTAPSYSLQDTLRDGVHHHPNPSHHRRPDSSSSASSATDWEGSGHATVLRRAAHQGHHLPPLPPPRQTLPMVESLRPLAPLAPVYNNINGTVVPTGAGGGKASIPNGGQKSLSVLESTSSDSEFERSFDLPGGSSSNAASISSKLTSLAHSLQSMRTRNKLKLGPQPHGQHSQQHQQQQHGQAQQQQQQQQQPQHGHMQHPLASTTMARTK
3) PKSLGIESSSSSESLNEEESGEEQQQQQQQQAIQQNQSQQPTQQQQQQQQQQQQQSSQQAQQVQQQQQQQQMKGTSSGVSPTPTNADSQQRSISPAVTVKSQASYNFSRPPLPLRRVPFL
4) PTDAEMLPLAEASPSDLGLGGKSHAPTMGPPMVGASGGVTGTSGKDGSGKSNQKTIQDSILRHM
5) SSLRGTIKVSRPGGGGESDAAFTPSPPVTIQNVDQNVSL
6) SSSASLANHIPPPRKPLSTLPDDERTLNLNANKLY
7) VSSGLTSNLSSSTENSLSTVVKRSGSPFSDLSRRDEGDGRSVADSQCSGSFRTDITGSTVTTSKSQQQVTSSQQQQQQQQQQQQQHQSSKQPPVQQQQQVVAAGGDQTGPASQPSVTMTTSTTVTQLRGKYII
2170
2290
2046
2576
2241
2539
2816
2225
2520
2165
2639
2279
2573
2948










Molecular Recognition Features






MoRF SequenceStartStop




1) LPLRRVPFLSTRSAFI
2) RNKLKL
2157
2467
2172
2472