<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08053

Description Uncharacterized protein
SequenceSASIAAQYALSFHLTVARTRSPYRIGVRLASSRSRRARVYVCVCGNSSVTMHTERRHRHRGARGTVTGHQTTGGTVIAATGTTAATATITTATQQPAIHPTVWEILSAELILSVAFLVRFLFTPPSVANEPEGTPELPAANRALFLEKVRQSNTACQNGDFSTAVQLYTDALGLDPGNHILYSNRSAARLKQGQFALALQDATRARELYPQWPKAYFRQGVALQCLGRYGEALAAFSAGLAQDPNSKQLLAGLVEASIKSPLRHALEPTFQQLKAMKLDQSPFVVISVVGQELLGAGQYHAAVTVLESALRIGSCSLKLRGSVFSALSSAHWALNQLDKAIAYMQQDLAVAKSLGDTAGECRAHGNLGSAYFSQGSYKEALTSHRYQLVLAMKCKDTQAAAAALTSLGHVYTAIGDYPNALASHKQCVQLVKQMGDRLQEAREIGNVGAVYLAMGEFDSAVDCHTQHLRLARKLGNQVEEARAYSNLGSSYHYKRNFTQAITYHESVLRIAQQLGDRAIEARAYAGLGHAARCGHDFVQAKRWHEKQLEMALAARDKVGEGRACSNLGIVYQLLGEHDAALKLHQAHLTIARQLQDKAGMGRAYGNIGNAYSAAGYYESAIKYHKQELIISKEVHDRSAEASTHGNLAVAYQALGAHDMALMHYRAHLNIARELKDTAGEACALLNLGNCLSSRQEFAQAVPYYEQYLMLSQELGDVAAEGKACHFLGYAHYCIGNYREAVRYYDQDLALAKDLQNKMNMGRAYCNLGLAHLALGNTGGALECQKYFLAIAHMTNHLPGKFRALGNIGDVLIRMGDVDEAIKMYQRQLALARQTRERGMEAAACGALGLAHRLLKKLDKALGYHTQELTLRQEMSDLPGECRAHGHLGAVHMALGNYTHAVKCYQEQLERAQELQDSAVEAQAFGNLGIARLNMGHYEDAIGYLEQQLGTLEQVNTATAQHDRARALGHLGDCYDALGDYHAEAIKCHERHLQLAIALQSARDQERAYRGLGNCYKSVGNLQEALVCLEKRLVVSHELGNAEAKAAAYGDLGGIHSALGNYEQAINCLEHQRDIARELGDRVLTSDAISGLGAVFHQMGDYDESLRLHKQDLELGESVSHATLQARACGNLGSVYDALRNYAESARYYEKQLTLTADRQTKAHACLALGRVYHSMEQVPQAIGFLRQGLAIAQSLNKLEDEAKLRYRLGLALVASGDDDAARQQMESAAQILESIRSDQVTPEARTQLYELQTACYQTLQRVLVGLGRTEEALVAAERCRSRMGADSNQSAENSLNNRKTLLTCSEYIFDTVNRSKTSIIYYSLAGADLYAWFLQPQKRIVRFHATKLDDQTLPMMKKKALMAPGHGGTTTGGGALALDKKGPTATGEAGGLVEQQSLLEQYINYVRDCLGVNSGSVLQEGDGSGWKSSNENLIDDFANERAGFLRMVNRNHLLNSSNYSLSSLFSLGSVGGSVASLQGSTRSIGSLQGSTRSRRSNMLPPWQGPSCLHVLYNLLLAPFEDLLPDISTTARIGRRELILVLEKELYLVPFAILRSGDEDGEYLSERCSLLTVPSLHTLRQKSRIKTREPAEGLNSALVIGGPKIPSSLSDTWGWSDSPASLQEAAMVSDMLNTKPLVSCSATKEAIVSELPAAECVHFAANVSWKLGAVVLSPGEVLDSQSQKRFYPNAAGELMGGDNDEETNDLSTANMEIPPLSDFILSAADLLSMKLSAKLVVLSSYHSVEPITGSGVANLAGSWLFAGTGAVLVSLWPVPETAAKILLRAFYSALLQGTRAARALAEAMQTVQHTKHFAHPANWAGFILIGGNVRLSNKVALIGQALCELMRTPDKCRDALRVCLHLVEKSLQRIHRGQKNAMYTTQKSIDNKAGPVSGWKDLLMAVGFRFEPAANGIPSSVFFPQSDPEDRLSQCSASLQALLGLSPTTLHALSKLVHGAEIADEIIGVMRNVVAQFPSKATDNESAIDVPLSVRLWRVSGCHELLASLGFDLMEVGQDQVTLRTGKQANRRNCQFVLQALLALFDTQEAPKSLGIESSSSSESLNEEESGEEQQQQQQQQAIQQNQSQQPTQQQQQQQQQQQQQSSQQAQQVQQQQQQQQMKGTSSGVSPTPTNADSQQRSISPAVTVKSQASYNFSRPPLPLRRVPFLSTRSAFISYVRRRGEPDGGQTDTAQSATNGGVSAIPNGNVLDTSLANTTDSELSDGYTTQQILLKSDHLAKGLGYSSLRGTIKVSRPGGGGESDAAFTPSPPVTIQNVDQNVSLALAHQTRIKNLYTNNGSLHGVTGTMNGAHGSTAPSYSLQDTLRDGVHHHPNPSHHRRPDSSSSASSATDWEGSGHATVLRRAAHQGHHLPPLPPPRQTLPMVESLRPLAPLAPVYNNINGTVVPTGAGGGKASIPNGGQKSLSVLESTSSDSEFERSFDLPGGSSSNAASISSKLTSLAHSLQSMRTRNKLKLGPQPHGQHSQQHQQQQHGQAQQQQQQQQQPQHGHMQHPLASTTMARTKLPVDQFGFLDRLSCRTEISSSASLANHIPPPRKPLSTLPDDERTLNLNANKLYFSPTDAEMLPLAEASPSDLGLGGKSHAPTMGPPMVGASGGVTGTSGKDGSGKSNQKTIQDSILRHMSREMTPTISEVYHERNIGLGLAPSLSKLLLSKNYDESAELGAKGGGSSVASVVAASAAAAAAAAAASMLNKPSAALTVGNLAEAMNEIEMNATTSSKLEEGACGICHSPSDLLCGCSATSTVAAVAAMTAALGANTMAKKSNSNKPWLSNVSPNIVKASDLTTADILEQQKQLKSSVSSGLTSNLSSSTENSLSTVVKRSGSPFSDLSRRDEGDGRSVADSQCSGSFRTDITGSTVTTSKSQQQVTSSQQQQQQQQQQQQQHQSSKQPPVQQQQQVVAAGGDQTGPASQPSVTMTTSTTVTQLRGKYIIDT
Length2950
PositionTail
OrganismAnopheles farauti
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.05
Grand average of hydropathy-0.342
Instability index48.05
Isoelectric point7.77
Molecular weight317972.97
Publications









Function






Annotated function


	RuleBase:RU364146

GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08053
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     152.03|      17|      17|    2079|    2095|       1
---------------------------------------------------------------------------
 2075- 2094 (32.32/13.60)	QqaiQQNQSQ.QPTQQ.QQQQ.....Q
 2095- 2113 (26.56/ 9.75)	Q..qQQQQSS.QQAQQvQQQQ.....Q
 2485- 2500 (33.25/14.22)	Q...QQ.QHG.QAQQQ.QQQQ.....Q
 2881- 2897 (34.37/14.97)	Q...QQVTSS.QQQQQ.QQQQ.....Q
 2898- 2920 (25.53/ 9.06)	Q...QQHQSSkQPPVQ.QQQQvvaagG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            21|    1013.80|      38|      39|     468|     505|       2
---------------------------------------------------------------------------
  348-  387 (51.66/23.62)	LA.VAKSLGDTAGECRAHGNLGSAYFSQGSY.KEAL.TSHryQ
  388-  425 (43.42/18.67)	LV.LAMKCKDTQAAAAALTSLGHVYTAIGDY.PNAL.ASH..K
  428-  465 (46.47/20.50)	VQ.LVKQMGDRLQEAREIGNVGAVYLAMGEF.DSAV.DCH..T
  468-  505 (54.55/25.35)	LR.LARKLGNQVEEARAYSNLGSSYHYKRNF.TQAI.TYH..E
  508-  545 (52.35/24.03)	LR.IAQQLGDRAIEARAYAGLGHAARCGHDF.VQAK.RWH..E
  548-  585 (50.76/23.08)	LE.MALAARDKVGEGRACSNLGIVYQLLGEH.DAAL.KLH..Q
  588-  625 (59.39/28.26)	LT.IARQLQDKAGMGRAYGNIGNAYSAAGYY.ESAI.KYH..K
  628-  665 (42.25/17.98)	LI.ISKEVHDRSAEASTHGNLAVAYQALGAH.DMAL.MHY..R
  668-  705 (49.62/22.40)	LN.IARELKDTAGEACALLNLGNCLSSRQEF.AQAV.PYY..E
  708-  745 (52.85/24.34)	LM.LSQELGDVAAEGKACHFLGYAHYCIGNY.REAV.RYY..D
  748-  785 (49.22/22.15)	LA.LAKDLQNKMNMGRAYCNLGLAHLALGNT.GGAL.ECQ..K
  788-  825 (45.83/20.12)	LA.IAHMTNHLPGKFRALGNIGDVLIRMGDV.DEAI.KMY..Q
  828-  865 (46.00/20.22)	LA.LARQTRERGMEAAACGALGLAHRLLKKL.DKAL.GYH..T
  868-  906 (52.32/24.02)	LT.LRQEMSDLPGECRAHGHLGAVHMALGNY.THAVkCYQ..E
  908-  945 (49.97/22.60)	LE.RAQELQDSAVEAQAFGNLGIARLNMGHY.EDAI.GYL..E
  951-  989 (44.81/19.51)	LE.QVNTATAQHDRARALGHLGDCYDALGDYhAEAI.KCH..E
  992- 1029 (43.75/18.87)	LQ.LAIALQSARDQERAYRGLGNCYKSVGNL.QEAL.VCL..E
 1032- 1069 (49.97/22.61)	LV.VSHELGNAEAKAAAYGDLGGIHSALGNY.EQAI.NCL..E
 1071- 1109 (41.24/17.37)	QRdIARELGDRVLTSDAISGLGAVFHQMGDY.DESL.RLH..K
 1112- 1149 (49.05/22.05)	LE.LGESVSHATLQARACGNLGSVYDALRNY.AESA.RYY..E
 1152- 1186 (38.32/15.61)	LT.LT...ADRQTKAHACLALGRVYHSMEQV.PQAI.GFL..R
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.89|      20|      22|    2576|    2597|       3
---------------------------------------------------------------------------
 2576- 2597 (31.27/26.82)	PTDAEmlPLAEASPSDLGLGGK
 2601- 2620 (38.62/25.67)	PTMGP..PMVGASGGVTGTSGK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.75|      20|      22|    2297|    2316|       4
---------------------------------------------------------------------------
 2297- 2316 (37.06/22.51)	LH.GVTGTMNGAHGSTAPSYS
 2321- 2341 (35.68/21.34)	LRdGVHHHPNPSHHRRPDSSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.39|      20|      21|    2822|    2841|       5
---------------------------------------------------------------------------
 2822- 2841 (32.46/18.46)	SNLSSSTENSLSTVV..KRSGS
 2844- 2865 (30.93/17.20)	SDLSRRDEGDGRSVAdsQCSGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.73|      19|      22|     231|     251|       6
---------------------------------------------------------------------------
  231-  251 (27.20/19.00)	EalAAFSAGL..AQDPNSKQLLA
  255-  275 (27.53/13.28)	E..ASIKSPLrhALEPTFQQLKA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.15|      11|      15|    1466|    1476|       7
---------------------------------------------------------------------------
 1466- 1476 (19.25/ 8.96)	SLGSVGGSVAS
 1483- 1493 (19.89/ 9.54)	SIGSLQGSTRS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     235.39|      73|     428|    1937|    2072|       8
---------------------------------------------------------------------------
 1232- 1293 (76.43/24.97)	..............LESIRS...DQVTpeARTQLYELQ.TACYQTLQrVLVGLGRTEEA..LVAAERCRSRMGADSNQSAEN
 1891- 1935 (43.81/105.09)	VSGWKDLLMAVGFRFEPAANgipSSVF..FPQSDPEDRlSQCSASLQ...................................
 1994- 2068 (115.16/65.65)	VSGCHELLASLGFDLMEVGQ...DQVT..LRTGKQANR.RNCQFVLQ.ALLALFDTQEApkSLGIESSSSSESLNEEESGEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.29|      15|      15|    2708|    2722|       9
---------------------------------------------------------------------------
 2708- 2722 (23.64/14.22)	LNK.PSAALTVGNLAE
 2724- 2739 (18.65/ 9.28)	MNEiEMNATTSSKLEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     279.89|      59|     211|    2155|    2220|      10
---------------------------------------------------------------------------
 1353- 1398 (50.66/28.13)	LPM...MKKKALMAPGHGGTTTGGGALAldkkgPTATGEA.....GGLVEQQSL..........
 1400- 1439 (48.97/26.78)	.......EQYINYVRDCLGVNSG..SVL.....QEGDGSGWKS.SNENLID.DFAN........
 2162- 2220 (95.43/60.87)	VPFLSTRSAFISYVRRRGEPDGGQTDTA.....QSATNGGVSAIPNGNVLDTSLANTTDSELSD
 2378- 2430 (84.83/52.37)	LPMVESLRPLAPLAPVYNNING...TVV.....PTGAGGGKASIPNGG..QKSL.SVLESTSSD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.79|      13|      15|    2637|    2649|      11
---------------------------------------------------------------------------
 2637- 2649 (23.61/15.21)	RHMSREMTPTISE
 2654- 2666 (20.18/11.72)	RNIGLGLAPSLSK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.61|      11|      15|    2453|    2463|      12
---------------------------------------------------------------------------
 2453- 2463 (17.67/ 9.17)	KLTSLAHSLQS
 2471- 2481 (21.94/13.76)	KLGPQPHGQHS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.18|      25|      31|     152|     176|      15
---------------------------------------------------------------------------
  152-  176 (44.96/28.12)	SNTACQNGDFSTAVQLYTDALGLDP
  186-  210 (42.22/25.90)	SAARLKQGQFALALQDATRARELYP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.88|      27|     417|    1301|    1334|      18
---------------------------------------------------------------------------
 1301- 1334 (32.39/42.81)	LLTCSEYifDTVNRSKTSIIyYSLAGadlyAWFL
 1734- 1760 (46.49/30.12)	LVVLSSY..HSVEPITGSGV.ANLAG....SWLF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08053 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AFISYVRRRGEPDGGQTDTAQSATNGGVSAIPNGNVLDTSLANTTDSELSDGYTTQ
2) LYTNNGSLHGVTGTMNGAHGSTAPSYSLQDTLRDGVHHHPNPSHHRRPDSSSSASSATDWEGSGHATVLRRAAHQGHHLPPLPPPRQTLPMVESLRPLAPLAPVYNNINGTVVPTGAGGGKASIPNGGQKSLSVLESTSSDSEFERSFDLPGGSSSNAASISSKLTSLAHSLQSMRTRNKLKLGPQPHGQHSQQHQQQQHGQAQQQQQQQQQPQHGHMQHPLASTTMARTK
3) PKSLGIESSSSSESLNEEESGEEQQQQQQQQAIQQNQSQQPTQQQQQQQQQQQQQSSQQAQQVQQQQQQQQMKGTSSGVSPTPTNADSQQRSISPAVTVKSQASYNFSRPPLPLRRVPFL
4) PTDAEMLPLAEASPSDLGLGGKSHAPTMGPPMVGASGGVTGTSGKDGSGKSNQKTIQDSILRHM
5) SSLRGTIKVSRPGGGGESDAAFTPSPPVTIQNVDQNVSL
6) SSSASLANHIPPPRKPLSTLPDDERTLNLNANKLY
7) VSSGLTSNLSSSTENSLSTVVKRSGSPFSDLSRRDEGDGRSVADSQCSGSFRTDITGSTVTTSKSQQQVTSSQQQQQQQQQQQQQHQSSKQPPVQQQQQVVAAGGDQTGPASQPSVTMTTSTTVTQLRGKYII
2170
2290
2046
2576
2241
2539
2816
2225
2520
2165
2639
2279
2573
2948










Molecular Recognition Features

Cannot open file output1!




MoRF SequenceStartStop




1) LPLRRVPFLSTRSAFI
2) RNKLKL
2157
2467
2172
2472