<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08026

Description Uncharacterized protein
SequenceMTTAVMMDYDFKMKTQQERAKVEDLFEYEGCKVGRGTYGHVYKARRKEGNDAKDYALKQIEGTGLSMSACREIALLRELKHPNVINLIRVFLSHTDRKVWLLFDYAEHDLWHIIKFHRAAKATKKPVMVPKGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGEGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIRKMPEHHTLTKDFKRSNYASCSLVKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDPYFSEDPMPTADVFAGCPIPYPKREFLTDEDQDDKGEKRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQNNQQQNNQQQNQQGNQQQQQQQAQNQQQQSGNVIKKYGGGGGGGVGGGQIGGGGGIDHNNAKRVRLSGPNGHPNNAQGGGMTQQEYHQQQQQNQQQQQQQNQMMFNNAQGGFQQRY
Length532
PositionKinase
OrganismAnopheles epiroticus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.08
Grand average of hydropathy-1.011
Instability index59.80
Isoelectric point8.93
Molecular weight61561.46
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08026
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     160.14|      15|      15|     378|     392|       1
---------------------------------------------------------------------------
  378-  392 (34.16/ 9.64)	QQQQQQQQQQQQQQQ
  394-  408 (34.16/ 9.64)	QQQQQQQQQQQQQQQ
  409-  422 (29.84/ 7.57)	QQQQQQQQ.NNQQQN
  423-  437 (29.58/ 7.45)	NQQQNQQGNQQQQQQ
  503-  517 (32.39/ 8.79)	HQQQQQNQQQQQQQN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     114.45|      33|      36|     127|     160|       2
---------------------------------------------------------------------------
  101-  122 (20.09/ 8.81)	.............LLFDYAE......HDLWhiiKFH..RAAKA
  127-  160 (59.68/45.25)	VMV...PKGMVKsLLYQILD.GIHYLHSNW...VLH..RDLKP
  165-  198 (34.68/20.69)	VMGegnERGRVK.....IADmGFARLF.NA...PLKplADLDP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.59|      13|      25|     456|     469|       3
---------------------------------------------------------------------------
  456-  469 (22.50/11.54)	GGGGGVGGGQiGGG
  484-  496 (28.09/11.28)	GPNGHPNNAQ.GGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.94|      16|      26|     245|     267|       4
---------------------------------------------------------------------------
  245-  262 (22.79/39.35)	EDIKtSNPYHHdQLDRIF
  274-  289 (31.16/17.88)	EDIR.KMPEHH.TLTKDF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08026 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PNKRITSEQAMQDPYFSEDPMPTADVFAGCPIPYPKREFLTDEDQDDKGEKRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQNNQQQNNQQQNQQGNQQQQQQQAQNQQQQSGNVIKKYGGGGGGGVGGGQIGGGGGIDHNNAKRVRLSGPNGHPNNAQGGGMTQQEYHQQQQQNQQQQQQQNQMMFNNAQGGFQQRY
326
532










Molecular Recognition Features






MoRF SequenceStartStop




1) AKRVRL
2) QQEYHQQQQ
3) QQSGNVIKKYGGG
477
499
444
482
507
456