<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08011

Description Mediator of RNA polymerase II transcription subunit 30
SequenceMAGQFPGGYQSPSGHRGNYNSPIIQQHLNQMNVPNPMGMMGFNQNNVMNNPQMQNVPGAGNQDMGLNPGLMQQAQQQQTAQGMQPNPQQVPSNPHQQAQNAMIGPGPGHPSAQQSPQMGGMQQQQQQQQPGGSIGPGNVMNNQQAQNQPPNQPGVGTAVQQQQKAEFNLLSLCRIGQETVQDIVSRFQEVFGILRSIQPPNGTNQGQLSSNDKKAKVQEQFRTIRLLFKRLRLLYDKCNDNCQQGMEYTHVESLIPLKGEIERTEPVHTEEYKKALQENRELVAMVQLKNKQLREIIDKIRLTIWEINTMLSMRRC
Length316
PositionHead
OrganismAnopheles dirus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.04
Grand average of hydropathy-0.871
Instability index51.35
Isoelectric point9.08
Molecular weight35379.63
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08011
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     101.41|      22|      22|     124|     145|       1
---------------------------------------------------------------------------
   30-   53 (34.65/11.88)	QMNVPNPMG.MMGfnQNNVMNN..PQM
   74-   98 (27.69/ 7.77)	AQQQQTAQGmQPN..PQQVPSNphQQA
  124-  144 (39.06/14.49)	QQQQQQPGG.SIG..PGNVMNN..QQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      98.76|      20|      47|      54|      73|       2
---------------------------------------------------------------------------
   54-   73 (39.27/12.15)	QNV...PGAGNQDMGLNP..GLMQQ
   99-  123 (28.22/ 7.10)	QNAmigPGPGHPSAQQSPqmGGMQQ
  146-  162 (31.28/ 8.50)	QNQ...P..PNQP.GVGT..AVQQQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08011 with Med30 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MAGQFPGGYQSPSGHRGNYNSPIIQQHLNQMNVPNPMGMMGFNQNNVMNNPQMQNVPGAGNQDMGLNPGLMQQAQQQQTAQGMQPNPQQVPSNPHQQAQNAMIGPGPGHPSAQQSPQMGGMQQQQQQQQPGGSIGPGNVMNNQQAQNQPPNQPGVGTAVQQ
1
161










Molecular Recognition Features






MoRF SequenceStartStop




NANANA