<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07994

Description Uncharacterized protein
SequenceMSSYHLSTRERLLTIVNDIEIVAKELIENTIAPKAQKMSSADHAQLVELLVLKDKELKSTLQLAAEQAGIEKNMDALREQVRKQDEEINQLQKQLKEAEQILATSIFQARQKLASIAKANKRPVSSEELIKFAHRISASHAICAPLTWQQGDLRRPYPTDIEMRLGLLGKSDLNINGHNLQHPSSLNEMHRNASSVTGAAGGAGGEIPASAQNQFAWHPSGELHMSMGAGGGSVSLDTRAHKDASQDDVEVISAMDPNRSVIGEEVDRIIQMQRLRASDGHRFFTRANSSNGTQNILLKVLSREHSGYLASGLNRRSRQQPFQEVPEQLQFCLKSIVPYCYLNGHIFMGLTSCGQFLLSYKLSYELDEVFANDFSSLHKYELYFWIYRPHMLLNKYFHVCLFDDHGVDGIKSVSITQWKTEGQLLIVHGGNLKDDADSYVTIVRVPKLGCLDCKQVRDAHEGDEQRQDILCISCNMTIHMKYRSTDSGPRFNPNFNLNCPGFVIMSENSFIHTINIELDTKRNQAGSNRTATLSSKYLGRVSPQKDVVVVAEEGKKVASRQQESSNSVPAKKYEPEAAKGEVASNALSDPAMSIAEQIIADFAEYETDMYETKCSIRNYPDNFDELIITSPIASGAAMADATTEPTTVAQVRLMNNRNNTNIELRLDGAASGAASSSSTSGTSEEVATVPSRKSFVTRIDLQSGDGSARQDTFGSTRIGGGNHHPLTAVPMLCDMSFTASSSTTAPAPSISSRSPLRRRFDLTESSSYVPNVPLTHQQSASLPLQQCVNNSANGANPVEPDADSAAKAYEFSEDNERCEKISAFRKRRLADKKYEFSEEPTSEENIEPFNRLRNQIRARVTAPGYSASHHHANYADLIPTTHHLHRASPNHGFRSPCGSPVGNRYLRSPPGIRSPSYYRHRSPSAQGGPPGAGSVVLIGGGSAAGTTPGSAAMKQLTKRTVQLDPRDFIQILSPGTGLSGTGTGDQAGSTPDIPKFFLDAIQKINEKKLANEQLQMLLDESNNENNINCDNQLPVKRAGSVEQASKPTAAELPTCTKKIVKIYVEEDDANSVVTTEDDDCISPGYHASLPMEVHGSCYSNMQIISQASFNKLNCPAVVVTQNSFDMEMFSFHVANYICTQDSKKYGILLDSAYELTHVCPLTETITCTTVLQFTANDIGHCKPKSCQNCSSTIDCQTHRKVYQCRSLFTWCITTGEWMILDYGNLSSGPYLEVKKLASNYSRLLKKLRAFTRKLFTSGKGESESDRTYEYLNHLRVLDSDTSKAKRRLTDLDNMIEFYLRLPRRIDDYSDSDTDSYGEEEEEEEEEEDDDDGDSSADDTLVGDASVASDTFR
Length1352
PositionMiddle
OrganismAnopheles dirus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.07
Grand average of hydropathy-0.522
Instability index52.67
Isoelectric point5.73
Molecular weight149373.28
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
protein ubiquitination	GO:0016567	IEA:InterPro
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07994
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.96|      24|      24|     805|     828|       1
---------------------------------------------------------------------------
  805-  828 (43.10/30.96)	AAKAYEFSEDNERCEKISAFRKRR
  830-  853 (43.86/31.66)	ADKKYEFSEEPTSEENIEPFNRLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.40|      23|      24|     183|     205|       2
---------------------------------------------------------------------------
  183-  205 (41.01/24.75)	P.SSLNEMHRNASSVTGAAGGAGG
  208-  231 (41.40/25.06)	PaSAQNQFAWHPSGELHMSMGAGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.86|      12|      30|     635|     646|       3
---------------------------------------------------------------------------
  635-  646 (21.32/14.04)	GAAMADATTEPT
  668-  679 (19.54/12.16)	GAASGAASSSST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.39|      23|      30|      42|      67|       4
---------------------------------------------------------------------------
   42-   67 (26.39/28.58)	DhaQLVELLVLKDKELKStL..QL.AAEQ
   75-  100 (27.00/15.99)	D..ALREQVRKQDEEINQ.LqkQLkEAEQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.62|      19|      24|     730|     748|       5
---------------------------------------------------------------------------
  730-  748 (35.31/21.20)	PMLCDMSFTASSSTTAPAP
  755-  773 (34.31/20.40)	PLRRRFDLTESSSYVPNVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.42|      17|      32|     885|     901|       6
---------------------------------------------------------------------------
  885-  901 (35.64/19.71)	HRASPNHGFRSPCGSPV
  920-  936 (31.77/16.72)	HRSPSAQGGPPGAGSVV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.80|      14|      35|     522|     537|       8
---------------------------------------------------------------------------
  522-  537 (19.89/17.45)	RNQAGSNRTAtlSSKY
  560-  573 (24.91/14.75)	RQQESSNSVP..AKKY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.65|      11|     624|     495|     510|      10
---------------------------------------------------------------------------
  487-  501 (17.11/ 6.64)	SGPRFnpnfNLNCPG
 1120- 1130 (18.54/10.82)	TQNSF....DMEMFS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.10|      19|      34|     647|     665|      11
---------------------------------------------------------------------------
  647-  665 (31.47/23.80)	TVAQVRLMNNRNN..TNIELR
  682-  702 (25.63/17.84)	TSEEVATVPSRKSfvTRIDLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      52.64|      10|     635|     704|     713|      13
---------------------------------------------------------------------------
  704-  713 (19.37/12.11)	GDGSARQDTF
 1332- 1341 (15.85/ 8.38)	GDSSADDTLV
 1342- 1351 (17.42/10.04)	GDASVASDTF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.36|      10|      24|     330|     339|      14
---------------------------------------------------------------------------
  330-  339 (19.56/12.16)	QFCLKSIVPY
  355-  364 (17.80/10.43)	QFLLSYKLSY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07994 with Med4 domain of Kingdom Metazoa
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