<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07987

Description Uncharacterized protein
SequenceMTTAVMMDYDFKMKTQQERAKVEDLFEYEGCKVGRGTYGHVYKARRKEGNDAKDYALKQIEGTGLSMSACREIALLRELKHPNVINLIRVFLSHTDRKVWLLFDYAEHDLWHIIKFHRAAKATKKPVMVPKGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGEGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIRKMPEHHTLTKDFKRSNYASCSLVKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDPYFSEDPMPTADVFAGCPIPYPKREFLTDEDQDDKGEKRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQNNQQQGQQNQQGNQQQQNAQQQQQSQMQQGGGGGGGQGGMDHNNAKRVRMSGPNGHPNNPQGGMTQQEYHQQQQQQQQNQQQQQQQQQQQQQNQMMFNNAQQGGFQQRY
Length515
PositionKinase
OrganismAnopheles dirus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.08
Grand average of hydropathy-1.040
Instability index61.77
Isoelectric point8.76
Molecular weight60040.88
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07987
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     137.23|      18|      18|     377|     394|       1
---------------------------------------------------------------------------
  377-  394 (40.07/12.12)	RQQQQQQQQQQQQQQQQQ
  396-  411 (29.94/ 7.35)	..QQQQQQQQQQQNNQQQ
  412-  429 (34.81/ 9.65)	GQQNQQGNQQQQNAQQQQ
  484-  500 (32.41/ 8.52)	QNQQQQQQQQQQQQQNQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.94|      16|      26|     245|     267|       3
---------------------------------------------------------------------------
  245-  262 (22.79/30.86)	EDIKtSNPYHHdQLDRIF
  274-  289 (31.16/13.93)	EDIR.KMPEHH.TLTKDF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      70.46|      12|      39|     464|     475|       4
---------------------------------------------------------------------------
  440-  451 (22.15/ 7.56)	GGGQGGMDHNNA
  464-  475 (25.43/ 9.59)	NNPQGGMTQQEY
  504-  515 (22.88/ 8.01)	NNAQQGGFQQRY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07987 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PNKRITSEQAMQDPYFSEDPMPTADVFAGCPIPYPKREFLTDEDQDDKGEKRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQNNQQQGQQNQQGNQQQQNAQQQQQSQMQQGGGGGGGQGGMDHNNAKRVRMSGPNGHPNNPQGGMTQQEYHQQQQQQQQNQQQQQQQQQQQQQNQMMFNNAQQGGFQQRY
326
515










Molecular Recognition Features






MoRF SequenceStartStop




1) NAKRVRMS
2) QQQNAQ
3) TQQEYHQQQQQQQQNQQQQ
450
421
471
457
426
489