<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07953

Description Mediator of RNA polymerase II transcription subunit 19
SequenceMFNNYGNTMASDPFRKVEQYSPKSSPREGELTGATNLMAHYGLEHSYSKFSGKKVKEQLSSFLPNLPGVIDGPGHLDNSSLRSVIEKPPIVGKELLPLTSVQLAGFRLHPGPLPEQYKHLKTAPTRKHKNKHKKHKHKDGVAPPE
Length145
PositionHead
OrganismAnopheles coluzzii
KingdomMetazoa
Lineage
Aromaticity0.07
Grand average of hydropathy-0.835
Instability index45.85
Isoelectric point9.75
Molecular weight16128.25
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP07953
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.95|      21|      35|      56|      76|       1
---------------------------------------------------------------------------
   56-   76 (38.55/23.23)	KEQLSSFLPNLPGVIDGPGHL
   93-  113 (37.40/22.35)	KELLPLTSVQLAGFRLHPGPL
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP07953 with Med19 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) RLHPGPLPEQYKHLKTAPTRKHKNKHKKHKHKDGVAPPE
107
145

Molecular Recognition Features

MoRF SequenceStartStop
1) PFRKVEQYS
2) QYKHLKTAPTRKHKNKHKKHKHKDGVA
13
116
21
142