<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07952

Description Uncharacterized protein
SequenceMACSSNSSSSSSSTTTPATVQVNLTSSQAPQVTVVKKIDVHGVPCFQVNNVTLVKRELVQPVAAAAPAPPPPPPPPPALPAPSVATVGTVPNELAAIGPLGDEYTEPSGSGTAAGGSSSRVVYPRYTNELYSGPPPPYSRAISSTVASSTQITPVQQQQQQQQTLQLSITKSSVGGLGVVGQQIQLLAKNLSEASVSAFKQYPASAVQTVSVLDRGSHEEPAAATASVASPSAPVGTPKLLYSVATTAGPRTAGTAITSTTTTTTANTPSASTALVDHLATGVPTITTTTGGTKTTVSASPSSSKSNVVKVLSNVKDIIMHVNAGQMSIVGDKTSLIPPVTERRPSAFAASTPGRSLLAITPAKSELPAEQHQQQQQQQQQPLCNTGMPTTKSEVEDLTGDYDHEVEYSGSWQEMDDHYADGEVRSQQWEGEEEEGAGGSSKRFRSASEQRETLPAAAASLDERMAPGEMATGGGGVACSSGSAMVTSVIRKTPQPVPCALSPPAPQQESKANVKRLVFRVAGNSATPTTVTISPAGPSSAPKIVRAWQGIKVEEDGTEPASSNADGIGGVAEPDRAANDASAINAAAAAAAPPPTATVSTSLDYGAIKQRRGGFRPPKKLAIKPKRTSVGEGPAPSTSGKQGAPMQVDEVEPAQPPAPTTMVMATALTTLADVHRPSTEIDVGAYNISYVGEAGETIYHPLPKRDGKTFGAQELLPAGGNGLAAGGESGADGSTAAPAHPDSRRMEVEEVEEDEEELGEEQMELEEDDEDAPELEEEDEEEEEDEEEEEDEDDEDDEEEEEKELEEDLIDDEEKEAHEHGELVQEEEEEEEVQLGSDEEEEEDDDEEEEEEEEDEEEEEEDEYDDDDVYEVEPRPVAGRYDASSQPEAHGRRRLLMVVSKPATATVTASEAAEPNGPYERPLPVDPAAEVVASGSLVVKRLPAAVPGTPDDEKDLLEAGPSTRMLERSGIPRPKFRITNADPFRPTAGLEPVRKTEVDAEPEYECSDSKDFLEQSLGSNPAVGGSTVAAHEQIQTTGEPLKAAKAEPCHDGQDDGQDTSASSFLDLSTVRKGGLPAGPVTTDTSSSNSSSNSSNSSSSHSTTNISLSQHSHSQLSHRHSHSAVSGGCKEGGEGSGTSGGTRSLLSSGSSHASTSMERAPSTESLNIRTDEKMPAKGEISEQESNGDMDMTSWNHRMYTVIENMPIYPSSYDLSTAQECWNLSSRNHVIFAVTDDFYHQQQQQQQQQQQQQQQHNSGSNNNSHGTTVNGQYMTSRVAFQFSSTGHQNLQQQQQQHQQHGSADAPLDGGMMQASKIEPPMDVDSDSGEVMPKLPFADMMVARMHEPPGAYDEQQQQTLHQPCEAKYEETIGTTSYFGVATCSAVPVMQQPTDDPVRPNRPKPSGSGVARTYRCTLCAKVFSSIKQRRLHQQCEHVDDLVALSSSHQQEMRGEEDNKPLMDGRQQQQLPQQQHQQQQQQQQQQQAQQQQQIYKKAPIPVCKLCNRTFKRFSNLAQHRKRYHLNRTVVKEEYVCQLCGEVFHTMAKMEWHKETHEKKPKSCPYCREKFIHRNSLTRHIRLSHTDKYAKLENKTEPCSICQQPYTKTSMRRHLETHTKERMAYACGICNKRFTTNWNLKQHKWTHTNPTMKPFQCTYCPSAFVRESDFVTHVNAHRSIRPYTCNHCGSQFIRKYNWIRHTREHEIDKGHRCDVCGRQFHRKYYLTEHKRIHTGERPFACNICGKTSATKTNHNKHVRIHHARDPLTAEGNQILFVARN
Length1774
PositionKinase
OrganismAnopheles coluzzii
KingdomMetazoa
Lineage
Aromaticity0.04
Grand average of hydropathy-0.796
Instability index64.02
Isoelectric point5.09
Molecular weight192810.67
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07952
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     176.38|      23|      23|     755|     777|       1
---------------------------------------------------------------------------
  755-  777 (42.54/23.73)	EEE.....LGEEQMELEEDDEDAPELEE
  780-  801 (40.01/21.86)	EEE.....EEDEEEEEDEDDEDDEE.EE
  802-  819 (29.58/14.17)	EKE.....LEEDLI....DDEE.KEAHE
  827-  854 (35.23/18.33)	EEEeeevqLGSDEEEEEDDDEEEEEEEE
  856-  873 (29.02/13.75)	EEE.......EE..EDEYDDDDVYEVE.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     687.83|     161|     226|     156|     316|       2
---------------------------------------------------------------------------
  156-  316 (262.05/131.31)	QQQQQQQQTL...QLSITKSSVGGL.GVVGQQI......QLLAKNLSEASVSAFKQYPASAVQTVSV...LDRG....SHEEPA..................AATASVASPSAPVGTPKLLYS...VATTAGPRTAGTAITSTTTTTT.ANTPSA....STALVDHLATGVPT...ITTTTGGTKTTVSAS.PS..SSKSNVVK.........VLSNVK
  374-  552 (197.49/96.97)	QQQQQQQQPLcntGMPTTKSEVEDLtGDYDHEVeysgswQEMDDHYADGEVRS.QQWE...............G....EEEEGAggsskrfrsaseqretlpAAAASLDERMAPGEMATGGGG...VACSSGSAMVTSVIRKTPQPVPcALSPPApqqeSKANVKRLVFRV.......AGNSATPTTVTIS.PAgpSSAPKIVR.........AWQGIK
 1246- 1423 (228.29/113.36)	QQQQQQQQHN...SGSNNNSH..GT.TVNGQYM.....tSRVAFQFSSTGHQNLQQQQQQHQQHGSAdapLDGGmmqaSKIEP.....................PMDVDSDSGEV.MPKLPFAdmmVARMHEPPGAYDEQQQQTLHQP.CEAKYE....ETIGTTSY.FGVATcsaVPVMQQPTDDPVRPNrPK..PSGSGVARtyrctlcakVFSSIK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|      99.62|      13|      25|    1526|    1538|       3
---------------------------------------------------------------------------
 1553- 1565 (22.34/10.48)	KKP..KSCPYCREKF
 1614- 1628 (18.64/ 7.50)	KERmaYACGICNKRF
 1647- 1658 (18.30/ 7.22)	.KP..FQCTYCPSAF
 1702- 1714 (22.20/10.36)	DKG..HRCDVCGRQF
 1730- 1741 (18.15/ 7.10)	ERP..FACNICGKT.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     288.43|      76|      84|     581|     664|       4
---------------------------------------------------------------------------
   63-  137 (97.93/43.15)	......AAAAPAPPPPPPPPP.ALpapSV.ATVGTV.....P.NELAAIGPlgdeyTEP........SGSGTAAGGSSSRVVYP.............RYTNELYSG.PPPP
  581-  659 (123.19/74.27)	ASAINAAAAAAAPPPTATVST.SL...DY.GAIKQRrgGFRP.PKKLAIKP.....KRT........SVGEGPAPSTSGKQGAP.............MQVDEVEPAqPPAP
  665-  752 (67.32/28.08)	ATALTTLADVHRPSTEIDVGAyNI...SYvGEAGET..IYHPlPKR....D.....GKTfgaqellpAGGNGLA..AGGESGADgstaapahpdsrrMEVEEVE.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     247.10|      54|      55|     946|     999|       5
---------------------------------------------------------------------------
  877-  926 (78.72/43.69)	VAG.RYDASSQ.PEAH.GRRRLLMVVSKPATA.TVTASEAAEPNGPYE..RPLPVD
  946-  999 (91.27/52.00)	VPG.TPDDEKDLLEAG.PSTRMLERSGIPRPKFRITNADPFRPTAGLEPVRKTEVD
 1001- 1055 (77.10/42.62)	EPEyECSDSKDFLEQSlGSNPAVGGSTVAAHEQIQTTGEPLK.AAKAEPCHDGQDD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      69.71|      12|      26|    1688|    1699|       6
---------------------------------------------------------------------------
 1688- 1699 (24.83/14.34)	RKYNWIRHTREH
 1716- 1727 (22.79/12.61)	RKYYLTEHKRIH
 1744- 1755 (22.09/12.02)	TKTNHNKHVRIH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.12|      13|      15|    1459|    1471|       8
---------------------------------------------------------------------------
 1459- 1471 (25.64/14.17)	DGRQQQQLPQQQH
 1476- 1488 (24.48/13.15)	QQQQQQQAQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      66.35|      18|      27|    1108|    1125|       9
---------------------------------------------------------------------------
 1099- 1119 (25.98/10.38)	SHSTTNislSQHSHSQL...SHRH
 1150- 1169 (19.71/ 6.14)	SHASTSmerAPSTES.L...NIRT
 1175- 1195 (20.67/ 6.79)	AKGEIS...EQESNGDMdmtSWNH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      90.51|      13|      27|    1601|    1613|      10
---------------------------------------------------------------------------
 1540- 1552 (24.01/12.41)	TMAKMEWHKE.THE
 1567- 1580 (16.97/ 6.78)	HRNSLTRHIRlSHT
 1601- 1613 (23.56/12.05)	TKTSMRRHLE.THT
 1630- 1642 (25.96/13.97)	TNWNLKQHKW.THT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.84|      10|      31|    1497|    1506|      11
---------------------------------------------------------------------------
 1497- 1506 (20.52/15.80)	VCKLCNRTFK
 1530- 1539 (21.32/16.77)	VCQLCGEVFH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.10|      16|      22|      28|      43|      12
---------------------------------------------------------------------------
   28-   43 (27.45/19.18)	QAPQVTVVKKIDVHGV
   47-   62 (26.65/18.39)	QVNNVTLVKRELVQPV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07952 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AVTDDFYHQQQQQQQQQQQQQQQHNSGSNNNSHGTTVNGQYMTSRV
2) FQFSSTGHQNLQQQQQQHQQHGSADAPLDGGMMQASKIEPPMDVDSDSGEVMPKLPFADMMVARMHEPPGAYDEQQQQTLHQPCEA
3) GEAGETIYHPLPKRDGKTFGAQELLPAGGNGLAAGGESGADGSTAAPAHPDSRRMEVEEVEEDEEELGEEQMELEEDDEDAPELEEEDEEEEEDEEEEEDEDDEDDEEEEEKELEEDLIDDEEKEAHEHGELVQEEEEEEEVQLGSDEEEEEDDDEEEEEEEEDEEEEEEDEYDDDDVYEVEPRPVAGRYDASSQPEAHGRRRLLMVVSKPATATVTASEAAEPNGPYERPLPVDPAAEVVASGSLVVKRLPAAVPGTPDDEKDLLEAGPSTRMLERSGIPRPKFRITNADPFRPTAGLEPVRKTEVDAEPEYECSDSKDFLEQSLGSNPAVGGSTVAAHEQIQTTGEPLKAAKAEPCHDGQDDGQDTSASSFLDLSTVRKGGLPAGPVTTDTSSSNSSSNSSNSSSSHSTTNISLSQHSHSQLSHRHSHSAVSGGCKEGGEGSGTSGGTRSLLSSGSSHASTSMERAPSTESLNIRTDEKMPAKGEISEQESNGDMDMTSWNHRMYT
4) GFRPPKKLAIKPKRTSVGEGPAPSTSGKQGAPMQVDEVEPAQPPAPTTMVMATALTTLADVHRPSTEIDVGAYNISY
5) GPPPPYSRAISSTVASSTQITPVQQQQQQQQTLQLS
6) IVGDKTSLIPPVTERRPSAFAASTPGRSLLAITPAKSELPAEQHQQQQQQQQQPLCNTGMPTTKSEVEDLTGDYDHEVEYSGSWQEMDDHYADGEVRSQQWEGEEEEGAGGSSKRFRSASEQRETLPAAAASLDERMAPGEMATGGGGVACSSGSAMVTSVIRKTPQPVPCALSPPAPQQESKANVKRLVFRV
7) LVQPVAAAAPAPPPPPPPPPALPAPSVATVG
8) SATPTTVTISPAGPSSAPKIVRAWQGIKVEEDGTEPASSNADGIGGVAEPDRAANDASAINAAAAAAAPPPTATVSTSLDYGAIKQR
9) TAGTAITSTTTTTTANTPSASTALVDHLATGVPTITTTTGGTKTTVSASPSSSKS
10) VALSSSHQQEMRGEEDNKPLMDGRQQQQLPQQQHQQQQQQQQQQQAQQQ
1231
1278
692
614
133
329
58
525
252
1438
1276
1363
1199
690
168
521
88
611
306
1486










Molecular Recognition Features






MoRF SequenceStartStop




1) AHGRRRLLMVVSKP
2) FRPPKKLAIKPKRT
3) KANVKRLVFRVA
4) KIVRAWQGIKVE
5) LDYGAIKQRR
6) RPKFRI
889
615
511
543
603
973
902
628
522
554
612
978