<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07950
Description |
Mediator of RNA polymerase II transcription subunit 20 |
Sequence | MGVTVLQPYPLEKSGAQTIDFLLKRVVALGAVPAGQFLVDCETYSSNPQLGPPKTVHILHNSEQPASVFSILDTGTKQIPLVTDGLFDLLMTRIAPAYTSKKQTKIESKGQRFEFGDFVIKLGSVTMSQNFKGVLVEVEYRPCLVPGSCWELMREFLQGFLGSNVSNSMPAYFTQRSSINPNHSKANEIYQPIDTINQYLEHFTNYRKQTMAPVGVRP |
Length | 218 |
Position | Head |
Organism | Anopheles coluzzii |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota>
Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae>
Anophelinae> Anopheles.
|
Aromaticity | 0.10 |
Grand average of hydropathy | -0.174 |
Instability index | 40.46 |
Isoelectric point | 8.38 |
Molecular weight | 24278.62 |
Publications | PubMed=30669388
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364152
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP07950
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 77.83| 26| 94| 20| 52| 1
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20- 52 (37.03/42.45) DFLLKrvvaLGAVPAGQ.F...LVDCEtYssNPQLGP
117- 146 (40.80/25.25) DFVIK....LGSVTMSQnFkgvLVEVE.Y..RPCLVP
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