<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07939

Description Mediator of RNA polymerase II transcription subunit 15
SequenceMAEDNSWKTSNFRQSVVNKINEAIQQTGMTSSKNGIEMENHVFHKARNKDEYLGFVARLILHVREMNTKHKNQQNAAAAAAAAAQQAQQDGGGNSSQQGGGGGGGGSGMPDPINALQNLASQGTRPQMMGQMGVGPGGPMGGQMGGAGQASNLLHSLRPQMQMGGMGGPMQGNRVGMGPGNQMGGMMGGPNQMQAMGPGGVVGPAGGGGVMGPGPNQMLGAGGAGGPGAGQQGNFVGMGANAMVRKPPEMMPGGNVYPGSGGAVRSVTPNNFLRQSPSPSVPSPVGPGAHGPPSHPGQMIPSPALIPSPNPHMGGVAQRSTIGQSPGGSLNTPGQPGGAVPSPLNPQDEQLYREKYRALTKYIEPLKRMIAKMENDDIDKIAKMKRLLEILSNPSVRIPLETLHKCEAALTSQLGSIRETPTNNPLVEAVSSSLQAATGNHTLQRTFRPCLEALFGPDIKNLPPPAKQSRLALDDTGAAVGTGGGDYPSTAPSCSLIEQEYNATPFLILVQKSLMARICKLPGLFTLSHLLDTWEMSVRQACSPNPTIVAPTGTSVLLGM
Length560
PositionTail
OrganismAnopheles coluzzii
KingdomMetazoa
Lineage
Aromaticity0.03
Grand average of hydropathy-0.389
Instability index51.50
Isoelectric point9.31
Molecular weight57787.21
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07939
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     292.19|      31|      32|     159|     189|       1
---------------------------------------------------------------------------
  127-  159 (37.33/ 8.13)	QM...M..G....Q...M......GVGPGGPMG..GQ......MGGagqasnllhslrP
  160-  190 (70.59/22.20)	QM.Q.M..GGMGGP...MQGNRV.GMGPGNQMG..GM......MGG............P
  192-  215 (36.84/ 7.92)	QM.QaMgpGGVVGP...AGGGGV..MGP.................G............P
  217-  248 (35.18/ 7.22)	QMlG.A..GGAGGPgagQQGNFV.GMG.AN.....AM......VRK...........pP
  249-  279 (43.36/10.68)	EM.M.P..GGNVYP...GSGGAVrSVTPNNFL...RQ......SPS............P
  280-  309 (33.98/ 6.71)	SV......PSPVGP.....G....AHGPPSHPG..QMipspalIPS............P
  310-  346 (34.92/ 7.11)	NP.H.M..GGVA......QRSTI.GQSPGGSLNtpGQ......PGG.....avpsplnP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.87|      17|      23|     410|     429|       2
---------------------------------------------------------------------------
  409-  428 (24.49/16.90)	ALTSqlgSIRETPTNN.......PLVE
  429-  452 (23.38/ 9.16)	AVSS...SLQAATGNHtlqrtfrPCLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.11|      16|      21|     363|     378|       4
---------------------------------------------------------------------------
  363-  378 (26.96/21.36)	IEPLKRMIAKMENDDI
  381-  396 (25.15/19.44)	IAKMKRLLEILSNPSV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07939 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MAEDNSWKTSNFRQSVVNKINEAIQQTGMTSSKNGIEMENHVFH
2) VREMNTKHKNQQNAAAAAAAAAQQAQQDGGGNSSQQGGGGGGGGSGMPDPINALQNLASQGTRPQMMGQMGVGPGGPMGGQMGGAGQASNLLHSLRPQMQMGGMGGPMQGNRVGMGPGNQMGGMMGGPNQMQAMGPGGVVGPAGGGGVMGPGPNQMLGAGGAGGPGAGQQGNFVGMGANAMVRKPPEMMPGGNVYPGSGGAVRSVTPNNFLRQSPSPSVPSPVGPGAHGPPSHPGQMIPSPALIPSPNPHMGGVAQRSTIGQSPGGSLNTPGQPGGAVPSPLNPQDEQLYREK
1
63
44
355










Molecular Recognition Features






MoRF SequenceStartStop




NANANA