<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07928

Description Mediator of RNA polymerase II transcription subunit 28
SequenceMIWQNSAVQNSPPSVYYLPEFITKEEECAIMQAVDKTPRPRWTQLSNRRLINYGGVPHPKGMIAEDIPSWLNHYVDRINQLNVYEEGIKANHVLINEYLPGQGIMPHLDGPLFFPTITTISCGSHTVLEYYEQTEDGSDLESKGALVRHHKTSILLEPRSLLIVKDDMYQKYLHSIAEQENDVIDDKVANLSMVAEMASSSNVGSGNLVDELEEAFQSCIHALTKEESATGIDKDEIKVEVDQTTLKFIDLARQMEAFFLQKRFLLSALKPDLLLKEENFDLKQEIGRKDELIRKHYEKIESWKQLLSDQQNFNKPIQSMPPDMRGNLAGGAPGGGPAGLMASGGMNLPMQWAWETVEGDAGGAGDAVEVEAVEEVVDEVACPSFTAAR
Length389
PositionHead
OrganismAnopheles christyi
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.07
Grand average of hydropathy-0.382
Instability index45.05
Isoelectric point4.74
Molecular weight43461.66
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
oxidoreductase activity	GO:0016491	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP07928
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.14|      18|      30|     314|     332|       1
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  314-  332 (31.50/17.29)	NKPIQSMPPDMRGNlAGGA
  347-  364 (36.64/16.82)	NLPMQWAWETVEGD.AGGA
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP07928 with Med28 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) QNFNKPIQSMPPDMRGNLAGGAPGGGPAGLMA
311
342

Molecular Recognition Features

MoRF SequenceStartStop
1) RRLINY
48
53