<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07918

Description Uncharacterized protein
SequenceMTTAVMMDYEFKMKTQQERAKVEDLFEYEGCKVGRGTYGHVYKARRKEGNDAKDYALKQIEGTGLSMSACREIALLRELKHPNVINLIRVFLSHTDRKVWLLFDYAEHDLWHIIKFHRAAKATKKPVMVPKGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGEGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIRKMPEHHTLTKDFKRSNYASCSLVKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDPYFSEDPMPTADVFAGCPIPYPKREFLTDEDQDDKGEKRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQNNQQQNNQQNQQGNQQQQNQQQQQSGNVNNKDDEDLQEHKHYLIIPMQQGGGAGVQGGGGGGMDHNNAKRVRMAGPNGHPNNSQGGMTQQEYHQQQQQQNQQQQNQMMFNSAQQGGFQQRY
Length530
PositionKinase
OrganismAnopheles christyi
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.08
Grand average of hydropathy-0.998
Instability index58.17
Isoelectric point8.32
Molecular weight61649.67
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07918
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     122.84|      17|      17|     377|     393|       1
---------------------------------------------------------------------------
  377-  393 (34.34/12.16)	RQQQQQQQQQQQQQQQQ
  407-  422 (26.42/ 7.61)	.QQQNNQQQNNQQNQQG
  423-  439 (30.11/ 9.72)	NQQQQNQQQQQSGNVNN
  498-  514 (31.97/10.80)	QQEYHQQQQQQNQQQQN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.54|      13|      27|     245|     262|       2
---------------------------------------------------------------------------
  245-  259 (18.86/14.15)	EDIKtSNPYHHdQLD
  274-  286 (24.69/11.19)	EDIR.KMPEHH.TLT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.95|      24|      27|     446|     472|       3
---------------------------------------------------------------------------
  446-  472 (36.96/21.90)	QeHKHYLIIPMqqGGGAGVQGGGGGGM
  473-  496 (45.99/19.01)	D.HNNAKRVRM..AGPNGHPNNSQGGM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     114.45|      33|      35|     127|     160|       4
---------------------------------------------------------------------------
  101-  122 (20.09/10.55)	.............LLFDYAE......HDLWhiiKFH..RAAKA
  127-  160 (59.68/53.59)	VMV...PKGMVKsLLYQILD.GIHYLHSNW...VLH..RDLKP
  165-  198 (34.68/24.57)	VMGegnERGRVK.....IADmGFARLF.NA...PLKplADLDP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07918 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PNKRITSEQAMQDPYFSEDPMPTADVFAGCPIPYPKREFLTDEDQDDKGEKRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQNNQQQNNQQNQQGNQQQQNQQQQQSGNVNNKDDEDLQEHKHYLIIPMQQGGGAGVQGGGGGGMDHNNAKRVRMAGPNGHPNNSQGGMTQQEYHQQQQQQNQQQQNQMMFNSAQQGGFQQRY
326
530










Molecular Recognition Features






MoRF SequenceStartStop




1) AKRVRMA
2) QEHKHYLIIP
477
446
483
455