<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07907

Description Uncharacterized protein
SequenceMLAKKSLKIQIMDEMSTQNVLLDACVNNCGKQFHLEVASREFETEFKKLLQKSQPKVTTKLKLTLKRWAEDVFKSDPQLDLIPSLYKKLREEGHDFNDPSVTPKRETTLSKDPNVVSSQQEEDDIAKAIELSLKEVKNTQSPKMMSSSGTVMAENGKPLPYSWDNSNNVFHLSQTASSLYPSTLLSTAPAAEPRKVRALYDFEAAEDNELTFQAGEIIMVLDDSDPNWWKGQNQRGEGLFPSNFVSADLSVEPESLITASGKGTKKSVQFSDEQKSDGDKDGQQKHLQPATVEINEEKVDRMLHLIHEADPEDPSQDTEEMLQLEQLVNQMGPLIDAELERVDRKHAQLTQLSGDLVDAVNLYHNLMREPDRSTMMSMSMGGPASAYATPGGYPGGSMNPMYGMPAMYQSLPGVGMYPMGPASGPSLPASMSGAQPMTSYNMSHLRHDMTQMNVGTMPQFSTPAQQHQQQHHQQQPHPTQGPMQNVSQNGPITNGMLSQGAPSTSMAGLSSQQQSTTTATPQTMPNMTGPPMPQQHGAIPQGFANPTSPPPVGMAGPPSHHQLQQVPPNPNQQTLPQMRPAGGPPPVSYPNYVPQQQQQHQPPVSQPVPQTAPQGMQPPTSTQPNQNHHPNQHVPMSMPPVHYPPSSGAPTHHHQHQQQQQQQQQFMPQMGPPMGNYAPMGAPMNMYPPGGPGVGGPLSINTNHQGPQNIPIYQQQRGLAETIASSVEGADKESIGALLVAVPELTKYSPEQWHRTAKLLSTEGLEMEKTLAIIGGHPSILVRPAEKIAESLHCWRSCQFGDANLKVLMSAHPYFLDYTNHGQLAQRVAFLHSHFETRKNVYRLFLNAPNLLVDEQHVTEAKIVYLLQTMRHEVLEVVKSCGFSYDLEHLRCRHTFLERLGLFKPRSLKADTNTPTGNPPLHQITDTSDKRFAVKVAYVTLEEYEVFQELFRRELEQDEHGETDDELDPEEAESEPKRSAYHKKGRFFGRFPQGCRVIVFPRIDVTFRWRPMMLAVRCLQHQILDTFAQSTKYEKAGRPFCHFAVLVFNGFNQNNVMNNPQMQGVPGQGNQDMGLNPGMMQQNQQQPGGQGMQSNTQQVVPTNQHQPGANQMVVQNPTHQTAQPSPQMGIQQQQQQQQQQQQQQGPNVGPGNPMNNPQTQSQSLPPNQPGGGTTVQQQQKAEFNLLSLCRIGQETVQDIVSRFQEVFGILRSIQPPNGTNQGQLSSNDKKAKVQEQFRTIRLLFKRLRLLYDKCNDNCQQGMEYTHVESLIPLKGEIERTEPVHTEEYKKALQENRELVAMVQLKNKQLREIIDKIRLTIWEINTMLSMRRC
Length1332
PositionHead
OrganismAnopheles christyi
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.06
Grand average of hydropathy-0.733
Instability index52.75
Isoelectric point6.21
Molecular weight148892.33
Publications









Function






Annotated function


GO - Cellular Component
endosome	GO:0005768	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
double-stranded DNA binding	GO:0003690	IEA:InterPro

GO - Biological Process
intracellular protein transport	GO:0006886	IEA:InterPro
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07907
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     566.79|      62|      62|     540|     601|       1
---------------------------------------------------------------------------
  363-  425 (52.80/13.89)	..............YHNLMR...EPD...............RS.TMMSM....SM..GGPasayaTPGGYPGgsmnpmYGMPAMYQSL..PGvGMypMGPAS..GP
  428-  482 (91.40/29.86)	PASM...SGaqPMTSYNMSHL....................RH.DMTQM...N.V..GTM.....PQFSTPA........QQHQQQHH..QQ.Q...PHPTQ..GP
  485-  550 (76.33/23.62)	NVSQ...NG..PITNGMLSQGAPSTSmaglssqqqstttatPQ.TMPNM........TGP.....PM................PQQHGaiPQ.GF..ANPTS..PP
  551-  602 (108.07/36.76)	PVGM...AG..PPSHHQLQQVPPNPN...............QQ.TLPQM...RPA..GGP.....PPVSYPN......YVPQQQQQHQ.................P
  603-  639 (70.51/21.22)	PVS....................QPV...............PQ.TAPQ.........GMQ.....PPTS...........TQPNQNHH..PN.QH..V.PMS..MP
  640-  689 (73.52/22.46)	PVHYppsSG..APTHHHQHQQQQQQQ...............QQ.FMPQM.........GP.....P...MGN......YAPMGAPMN...............myPP
  692-  717 (38.06/ 7.79)	P.GV...GG..PLS........INTN...............HQ.G.PQ....................NIPI......Y..QQQR.....................
 1095- 1146 (56.11/15.26)	................NTQQVVPTNQ...............HQpGANQMvvqNPThqTAQ.....PSPQMGI......QQQQQQQQQ...QQ.Q......QQ..GP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.70|      28|      45|      54|      82|       2
---------------------------------------------------------------------------
   54-   82 (41.81/39.20)	QPKVTTKLKLTLKRwAEDVFKSDPQLDLI
   98-  125 (47.89/37.20)	DPSVTPKRETTLSK.DPNVVSSQQEEDDI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     120.31|      37|      45|     897|     933|       3
---------------------------------------------------------------------------
  897-  933 (63.64/34.21)	LERLGLFKP...RSLKADTNTPTGNPPLHQITDTSDKRFA
  941-  980 (56.66/29.64)	LEEYEVFQElfrRELEQDEHGETDDELDPEEAESEPKRSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.66|      18|      18|     286|     303|       5
---------------------------------------------------------------------------
  286-  303 (30.46/21.72)	HL.QPATVEINEEKVDRML
  304-  322 (28.20/19.43)	HLiHEADPEDPSQDTEEML
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.94|      12|      20|     326|     337|       6
---------------------------------------------------------------------------
  326-  337 (22.28/12.18)	QLVNQMGPLIDA
  348-  359 (20.67/10.76)	QLTQLSGDLVDA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     172.23|      36|      39|     804|     839|       7
---------------------------------------------------------------------------
  773-  803 (42.78/26.25)	....IIG.GHPSILVRPAE.KIAESLHCWRSCQFGDA
  804-  839 (60.06/40.03)	NLKVLMS.AHPYFLDYTNHGQLAQRVAFLHSHFETRK
  840-  872 (47.53/30.05)	NVYRLFL.NAPNLLVDEQHVTEAKIVYLLQT...MRH
  874-  896 (21.87/ 9.58)	VLEVVKScGFSYDLE...H..LRCRHTF.........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.86|      16|      18|    1149|    1164|       8
---------------------------------------------------------------------------
 1149- 1164 (30.38/15.01)	GPGNPMNNPQTQSQSL
 1170- 1185 (25.48/11.17)	GGGTTVQQQQKAEFNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      86.66|      20|      59|     174|     193|       9
---------------------------------------------------------------------------
  174-  193 (31.82/16.01)	QTASSLYPSTLLSTAP...AAEP
  212-  233 (22.91/ 9.61)	FQAGEII.MVLDDSDPnwwKGQN
  234-  253 (31.94/16.10)	QRGEGLFPSNFVSADL...SVEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.57|      16|      49|     981|    1000|      10
---------------------------------------------------------------------------
  981- 1000 (26.60/29.38)	YHKKGRFFGRFPqgcrVIVF
 1033- 1048 (31.97/21.20)	YEKAGRPFCHFA....VLVF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07907 with Med30 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EGHDFNDPSVTPKRETTLSKDPNVVSSQQE
2) EKVDRMLHLIHEADPEDPSQDTEEMLQLEQLVNQ
3) GVGMYPMGPASGPSLPASMSGAQPMTSYNMSHLRHDMTQMNVGTMPQFSTPAQQHQQQHHQQQPHPTQGPMQNVSQNGPITNGMLSQGAPSTSMAGLSSQQQSTTTATPQTMPNMTGPPMPQQHGAIPQGFANPTSPPPVGMAGPPSHHQLQQVPPNPNQQTLPQMRPAGGPPPVSYPNYVPQQQQQHQPPVSQPVPQTAPQGMQPPTSTQPNQNHHPNQHVPMSMPPVHYPPSSGAPTHHHQHQQQQQQQQQFMPQMGPPMGNYAPMGAPMNMYPPGGPGVGGPLSINTNHQGPQNIPIYQQQRGLAETIASSV
4) NVMNNPQMQGVPGQGNQDMGLNPGMMQQNQQQPGGQGMQSNTQQVVPTNQHQPGANQMVVQNPTHQTAQPSPQMGIQQQQQQQQQQQQQQGPNVGPGNPMNNPQTQSQSLPPNQPGGGTTVQQQQ
5) SGKGTKKSVQFSDEQKSDGDKDGQQKHLQPATVEI
6) VNLYHNLMREPDRSTMMSMSMGGPASAYATPGGYPGG
92
297
413
1055
260
360
121
330
727
1179
294
396










Molecular Recognition Features






MoRF SequenceStartStop




1) LYKKLRE
85
91