<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07895

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMIMDNTKTTSKTTLLKLMLLRAWKERWTDCQWGINVKTVLTRGVSGDVYNLADAIIQQAVVGSGANMLFLSYLKHSLCAHLISHAAVLNRIGKYEHFDKLHCLIALLDFLQSIIDGVTCRSKQEEALLTKATVSLVNWLLQIYECALNTYAENRVLSCEEEEVVQKVAVVLERIVESPFLLGVIAIGRFEDVEQFMTLQKRFNGINNLTLTTGYVAHAGSGQKNVTVTDYMRKLVHLEVDVLQMKLFDGGMVEPITYSMQPLIAIEVLLNPMCDTAVYVAQFINLKRLKGYSYARLYCEIIRGCLISLNNVEGTLKESLLCAFAFIKVPHILRQIHAKTNGKEQKDETTNATYSVEMVDAVEMLLQDSPVLDYMDMKCACNVVECLLKEMVKHNLLTETHVTYFVSLREPITLGLQKLESGNTQLTLMLKFVFRVESPLAGMLKALSADYSKVQDALLAMLCQVLTGNSLDLVLSVASVEGKFKAFISGLLKCNDYAKQATCVEMGKASATRGALFDVTFMILACIAQSYGSDVILAEGGNSFFEKWVRDFMVEKKKTKSPMNMVKQADPVVLEKLIMALNNVEAGGDLKAANLRWEDVCFTIPALLHQVLMAWENETFSPVKIKKMLDGLKTHFCSFAVCASSWLCAYMHAARPDEQVKPMNMVQQLCSAPSGPQADEWQQQDYCKERFGLMGQLIRRMQQEFQRSPQVNPKLRALFPNQLHVVSHLPAEEQFEDAWKAIAERGWLPIETIFLLETLLQSCGPVWLMEKLIAKLFLCKYVRDLNKTMDIIFAIMHLDIERCTIALLSQLVPMMLLNSKQTPEIVDPQSRILAKLCVYAIIVTMEASLTASKKRPRGAATGLDVEDPLDSLCSSAKLRKLDIDGMGVGCDGTVGLGNEFGLDGALEAVAGFGEPVAAPATIREPLQGCLQTLFRTFTQYISTDELSPKVYFVFQFLSLLVESGRERIMCVLKLLPNGLLQNLLKINATDEMTVGFILRLYDLSTGSGRQLAMSDICLLRNIQMRKDSIKL
Length1030
PositionTail
OrganismAnopheles atroparvus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.07
Grand average of hydropathy0.151
Instability index38.62
Isoelectric point6.34
Molecular weight115190.92
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07895
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     126.72|      40|      47|     927|     973|       1
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  927-  972 (61.61/60.15)	GCLQTLFRtftqYISTDELSpkVYFVFQFLSLLVESGRERIM...CVLK
  977- 1019 (65.10/40.54)	GLLQNLLK....INATDEMT..VGFILRLYDLSTGSGRQLAMsdiCLLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     571.98|     182|     230|     449|     639|       2
---------------------------------------------------------------------------
  449-  639 (290.09/197.79)	DYSKVQDALLAMLCQVLTGnslDLVLSvASVEGKFKA.FISGLLKCNDYAKQATCVEMGKASATRGALFDVTFMILACIAQSYGSdVILAEG..GNSFFEKWVRDFMVEKKKTKSPMNM.VKQADPVVLEKLI.MALNNVEAGGDLKAANLR.WEDVC.FTIPALLHQVLMAWENE...TFSPVKIKKMLDGLkthfCSFA
  684-  875 (281.90/169.81)	DYCKERFGLMGQLIRRMQQ...EFQRS.PQVNPKLRAlFPNQLHVVSHLPAEEQFEDAWKAIAERGWLPIETIFLLETLLQSCGP.VWLMEKliAKLFLCKYVRDLNKTMDIIFAIMHLdIERCTIALLSQLVpMMLLNSKQTPEIVDPQSRiLAKLCvYAIIVTMEASLTASKKRprgAATGLDVEDPLDSL....CSSA
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.59|      21|      38|     119|     142|       3
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  119-  142 (30.62/27.19)	CrskQEEALLTKATVSL.....VNWLLQI
  158-  183 (28.97/17.15)	C...EEEEVVQKVAVVLeriveSPFLLGV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      99.87|      18|      49|     349|     366|       4
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  256-  270 (19.17/ 9.75)	...TYSMQP...LIAIEVLLN
  349-  366 (29.49/19.18)	TNATYSVEM...VDAVEMLLQ
  369-  388 (24.14/14.29)	PVLDY.MDMkcaCNVVECLLK
  399-  416 (27.08/16.98)	THVTYFVSL...REPITLGLQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07895 with Med24 domain of Kingdom Metazoa
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