<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07885

Description Uncharacterized protein
SequenceMEESDESDTELSNIEKTVSAVALTNGVNMREDRTASKGAPRPMSWEGELSEPEEPMLVDNENSSSGSSVGKLANAPSSPVAMVVPKQEEDHDPPTSGPGITEPLALTTTSHVIGYSNVIQHGHGLRSAHGGSGGNSSSSNSPLPHRMLIKPEAGLPLINPGLAYNVVGLAHPSCNIPASVSGAPSMKKGLPDAINLKYELPPCGVGDPGGGGGSALPPNAIHSPLLVRSKTTLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHSIFAGGGIGNGGPGIASFNGSPLHHSVLYKPMLDSEQHQHHQQHQHHQQHQQHQQHQQHQQHQQHQQQHHHQHQQHQQHQQHQQHQQHQQHQQHQQQHQQHQQQQQHPQQQQQALKQEELLYDGEHLPSPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAACPVAIATRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPGPLVNSAGMQGQGADSPGVAPFQYGGSVRSPYVAGGGGVGVASGPQMKVEAQESTSGMTMSGGGNGGSNGGVNGINNGPSGEGNSASSVDGNHMPPGIPVLLQEIMDVEPLWQYNAAELARLNQPPPVTSSSAIANNPLLSSAGISTENSPDLIANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCYRSITTPGEIKISLGKSITLEKVKNSGLQTCIERMLNLTDHLRRLRVDKYEYVAMKVIVLLSSDTSELKESEKVRASQEKALQALQAYTLAYYPKSPAKFGELLLRIPELQRTCQVGKEMLNIKSKDDEEPSFNLLMELLRGEH
Length877
PositionKinase
OrganismAnopheles atroparvus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.05
Grand average of hydropathy-0.607
Instability index56.88
Isoelectric point6.88
Molecular weight95130.45
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
nuclear receptor activity	GO:0004879	IEA:InterPro
sequence-specific DNA binding	GO:0043565	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07885
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     144.36|      16|      16|     352|     367|       1
---------------------------------------------------------------------------
  335-  349 (31.65/10.59)	.EQHQHHQQHQHHQQH
  352-  367 (42.12/15.95)	HQQHQQHQQHQQHQQQ
  375-  388 (32.63/11.09)	HQQHQQHQQHQQHQ..
  397-  412 (37.97/13.82)	HQQHQQQQQHPQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      63.53|      13|      15|     239|     251|       2
---------------------------------------------------------------------------
  239-  251 (24.88/13.54)	SPDSAIHS.VYTHS
  256-  268 (21.67/10.78)	SPLTSRHA.PYTPS
  272-  285 (16.97/ 6.75)	NNSDASHSsCYSYS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.38|      20|      22|     683|     703|       4
---------------------------------------------------------------------------
  683-  703 (31.92/27.28)	LIANLcNIADHRLYKIVKWCK
  707-  726 (37.46/25.52)	LFKNI.SIDDQICLLINSWCE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.70|      30|      32|     151|     182|       5
---------------------------------------------------------------------------
  117-  164 (32.37/15.62)	NVIqhghGLrsAHGGSGGNSSSSNsplphrmlikP..EAGLP.LINpgLAY
  165-  198 (44.33/17.01)	NVV....GL..AHPSCNIPASVSG.........aPsmKKGLPdAIN..LKY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.92|      18|      24|     527|     546|       7
---------------------------------------------------------------------------
  527-  546 (30.23/19.38)	YTLPG....PLVnsAGMQGQGADS
  552-  573 (29.69/13.31)	FQYGGsvrsPYV..AGGGGVGVAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.26|      20|      31|     574|     593|       8
---------------------------------------------------------------------------
  574-  593 (36.19/17.97)	GPQMKVEAQESTSGMTMSGG
  608-  627 (38.07/19.26)	GPSGEGNSASSVDGNHMPPG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07885 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HSPIQARHSIFAGGGIGNGGPGIASFNGSPLHHSVLYKPMLDSEQHQHHQQHQHHQQHQQHQQHQQHQQHQQHQQQHHHQHQQHQQHQQHQQHQQHQQHQQHQQQHQQHQQQQQHPQQQQQALKQEELLYDGEHLPSPGIS
2) MEESDESDTELSNIEKTVSAVALTNGVNMREDRTASKGAPRPMSWEGELSEPEEPMLVDNENSSSGSSVGKLANAPSSPVAMVVPKQEEDHDPPTSGPGITEPLALT
3) SGPQMKVEAQESTSGMTMSGGGNGGSNGGVNGINNGPSGEGNSASSVDGNH
4) SNVIQHGHGLRSAHGGSGGNSSSSNSPLPHRMLIKPE
5) VRSKTTLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSP
292
1
573
116
227
432
107
623
152
290










Molecular Recognition Features






MoRF SequenceStartStop




1) PRPMSWEGELSEPEEPM
40
56