<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07877

Description Mediator of RNA polymerase II transcription subunit 30
SequenceMSGQFPGGYQSPSGHRGNYNSPMIQQQLNQMNVPNQMGMMGFNQNNVMNAQQMQGGPGQGGPEMGLNQNMMQQNQQQGAQGIQSNPQQIPTNQHQQGQNQMVGQNQQHQAPQPSPQMVMQQPGGNVGPGNVMNNPQAQQNQPPPNQPSGGAAVQQQQKAEFNLLSLCRIGQETVQDIVSRFQEVFGILRGIQPPNGTNQGQLSSNDKKAKVQEQFRTIRLLFKRLRLLYDKCNDNCQQGMEYTHVESLIPLKGELERSEPVHTEEYKKTLQENRELVAMVQLKNKQLREIIDKIRLTIWEINTMLSMRRC
Length310
PositionHead
OrganismAnopheles atroparvus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.04
Grand average of hydropathy-0.941
Instability index47.50
Isoelectric point9.08
Molecular weight34912.05
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07877
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     135.67|      22|      22|      38|      59|       1
---------------------------------------------------------------------------
   14-   36 (33.26/ 9.78)	G.HRG.NYNS.........PMIQQqlnQM.N..VPNQ
   38-   59 (49.01/17.94)	G.MMGFNQNN.........VMNAQ...QMQG..GPGQ
   61-   77 (26.84/ 6.45)	GpEMGLNQ.N.........MMQQN...Q.......QQ
  100-  130 (26.55/ 6.30)	Q.MVGQNQQHqapqpspqmVM..Q...QPGGnvGPGN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     185.15|      57|      60|     172|     231|       2
---------------------------------------------------------------------------
  143-  166 (24.16/ 6.17)	.....................PPNQPSGG........AAVQQQ...QKA...EFNLLSL....
  172-  231 (86.82/47.11)	ETVQdiVSRFQEVFGILRGIQPPNGTNQGqLSSNDKKAKVQEQ...FRTIRLLFKRLRLLYDK
  241-  293 (74.17/32.79)	EYTH..VESLIPLKGELERSEP........VHTEEYKKTLQENrelVAMVQLKNKQLREIIDK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07877 with Med30 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MSGQFPGGYQSPSGHRGNYNSPMIQQQLNQMNVPNQMGMMGFNQNNVMNAQQMQGGPGQGGPEMGLNQNMMQQNQQQGAQGIQSNPQQIPTNQHQQGQNQMVGQNQQHQAPQPSPQMVMQQPGGNVGPGNVMNNPQAQQNQPPPNQPSGGAAVQQ
1
155










Molecular Recognition Features






MoRF SequenceStartStop




NANANA