<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07871

Description Uncharacterized protein
SequenceMGDFLYSGSVLANESCVSNPSLLDTLSINNLLNIKHLTTGADIGSGTGVSDSLGTIGESSSSSSSVSGLGERSKNNNASTIAKMASGGGAGHGGALSLGGGSDGDGQGLLMTSSVAASSCGVGGLSSVSSIITTAMSSDGCSLSLALGSGGAGGADDATVTSSLLNGGSISSPSIGVSLGVNGLGSSNGGSANGNNNGTGHSHSNNGSSGNGSNAGSNGNGNGVGCNPNSANNNLLLDSAADQLQLQSVAEELSLKASDLGCLSVTSNLMNGSSHIGSCLAPSGLGFGATPDHSSPWSTGPDEAGQGGTAGGHLSMNGLGGFQNFSSNLYNGAVVAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQQHQQRRAITASHGGFPNHHHGISPSGLSAHSNAMLQQQQQQHQQQQQQQQQQQQNQYKNSYPSWSNPGPWSQQQSSQQQHHQQQQQQQQVHQHQQQQQQSALSSWNRGRGGSGVGVGSGGGGGGGGMGGGFPGPLDVAGIDENRDPFLSSYQVSERTSFLCV
Length542
PositionTail
OrganismAnopheles atroparvus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.03
Grand average of hydropathy-0.618
Instability index54.64
Isoelectric point5.72
Molecular weight54547.61
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
histone methyltransferase activity (H3-K79 specific)	GO:0031151	IEA:InterPro
GO - Biological Process
regulation of cell cycle	GO:0051726	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats
>MDP07871
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     164.12|      15|      15|     348|     362|       1
---------------------------------------------------------------------------
  348-  362 (36.46/13.15)	QQQQQQQQQQQQQQQ
  364-  378 (36.44/13.14)	QQQQQQQQQHQQQQQ
  423-  437 (34.43/12.05)	QQQQQQQQQQQQNQY
  452-  466 (32.68/11.10)	QQQSSQQQHHQQQQQ
  467-  479 (24.10/ 6.45)	QQQVHQHQQQQQQ..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     157.60|      34|      34|     121|     154|       2
---------------------------------------------------------------------------
   30-   67 (34.89/ 8.75)	NLLNIKHLTTGADIGSGTGVSDSLGTIGESS........ssssS..VS
  124-  168 (48.78/15.32)	GLSSVSSIITTAMSSDGCSLSLALGSGGAGGaddatvtssllnG...G
  201-  225 (30.29/ 6.57)	HSHS.....NNGSSGNG.S...NAGSNGNG..............ngVG
  278-  320 (43.64/12.89)	SCLAPSGLGFGATPDHSSPWSTGPDEAGQGG...tagghlsmnG..LG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.50|      13|     103|     160|     176|       6
---------------------------------------------------------------------------
  160-  176 (18.14/11.03)	VTSSLLNggsiSSPSIG
  265-  277 (25.36/13.64)	VTSNLMN....GSSHIG
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP07871 with Med15 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQQHQQRRAITASHGGFPNHHHGISPSGLSAHSNAMLQQQQQQHQQQQQQQQQQQQNQYKNSYPSWSNPGPWSQQQSSQQQHHQQQQQQQQVHQHQQQQQQSALSSWNRGRGGSGVGVGSGGGGGGGGMGGGFPGPLDVAGIDENRDPFLSSY
2) LAPSGLGFGATPDHSSPWSTGPDEAGQGGTAGGHLSMNG
3) SSNGGSANGNNNGTGHSHSNNGSSGNGSNAGSNGNGNGVG
340
280
186
531
318
225

Molecular Recognition Features

MoRF SequenceStartStop
1) HQQRRAITASH
2) NRDPF
3) QNQYKNSYPSWSNPGPWS
4) SALSSWNRGRG
382
523
434
480
392
527
451
490