<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07850

Description Uncharacterized protein
SequenceMTTAVMMDYEFKMKTQQERAKVEDLFEYEGCKVGRGTYGHVYKARRKEGNDAKDYALKQIEGTGLSMSACREIALLRELKHPNVINLIRVFLSHTDRKVWLLFDYAEHDLWHIIKFHRAAKATKKPVMVPKGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGEGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIRKMPEHHTLTKDFKRSNYASCSLVKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDPYFSEDPMPTADVFAGCPIPYPKREFLTDEDQDDKGEKRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQNNQQNQQGNQQQQQQNQQQSGNPMQQGGGAGGAGGGGQGGGGMDHNNAKRVRLAGPNGHPNNSQGGMTQQEYHQQQQQQNQQQQQQNQMMFNSGQQGGFQQRY
Length515
PositionKinase
OrganismAnopheles arabiensis (Mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.08
Grand average of hydropathy-0.991
Instability index57.91
Isoelectric point8.76
Molecular weight59583.38
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07850
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     108.43|      18|      18|     376|     393|       1
---------------------------------------------------------------------------
  376-  393 (38.26/11.44)	KRQQQQQQQQQQQQQQQQ
  395-  412 (37.55/11.11)	QQQQQQQQQQQQQQQQQQ
  484-  500 (32.62/ 8.81)	YHQQQQQQNQQQQQQNQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.05|      14|      25|     442|     455|       5
---------------------------------------------------------------------------
  442-  455 (28.06/14.05)	AGGAGGGGQGGGGM
  466-  479 (26.99/13.22)	AGPNGHPNNSQGGM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.42|      13|      25|     278|     290|       6
---------------------------------------------------------------------------
  278-  290 (24.88/16.80)	KMPEHHTLTKDFK
  301-  313 (22.53/14.53)	KYMERHKIKPDSK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.00|      12|      18|     339|     350|       8
---------------------------------------------------------------------------
  339-  350 (23.63/15.52)	PYFSEDPMPTAD
  358-  369 (22.37/14.32)	PYPKREFLTDED
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07850 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PNKRITSEQAMQDPYFSEDPMPTADVFAGCPIPYPKREFLTDEDQDDKGEKRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQNNQQNQQGNQQQQQQNQQQSGNPMQQGGGAGGAGGGGQGGGGMDHNNAKRVRLAGPNGHPNNSQGGMTQQEYHQQQQQQNQQQQQQNQMMFNSGQQGGFQQRY
326
515










Molecular Recognition Features






MoRF SequenceStartStop




1) GFQQRY
2) MDHNNAKRVRLAGPNGH
3) TQQEYHQQQQ
510
455
480
515
471
489