<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07837

Description Uncharacterized protein
SequenceMSNAVMMDYEFKMKKQQERAKVEDLFEYEGCKVGRGTYGHVYKAHRKESNDTKDYALKQIEGTGLSMSACREIALLRELKHPNVINLIRVFLSHTDRKVWLLFDYAEHDLWHIIKFHRAAKATKKPVMVPKGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGEGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIRKMPEHHTLTKDFKRSNYANCSLVKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDPYFSEDPMPTADVFAGCPIPYPKREFLTDEDQDDKGESKRQQQQQQQQANQQAQQNQQQQANHQNQQQNQQQQANQQNQQSQQQQQQQQQQQMQQQQQQQAQSSGMDHSTAKRVRMSGPNGQPGNGMNQQDYQVQQAQQAAAAAAAAQQQQQQQQQQQQQQMMFNNPQQGGFQQRY
Length514
PositionKinase
OrganismAedes albopictus (Asian tiger mosquito) (Stegomyia albopicta)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Culicinae> Aedini> Aedes> Stegomyia.
Aromaticity0.08
Grand average of hydropathy-0.957
Instability index56.72
Isoelectric point8.76
Molecular weight59858.82
Publications
PubMed=26483478

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07837
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      80.54|      15|      23|     397|     411|       1
---------------------------------------------------------------------------
  402-  417 (24.52/ 6.42)	QNQQQNQQQQ.aNQQNQ
  427-  441 (29.70/ 9.22)	QQQQMQQQQQ..QQAQS
  486-  502 (26.32/ 7.39)	QQQQQQQQQQqqQQMMF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     114.45|      33|      35|     127|     160|       3
---------------------------------------------------------------------------
  101-  122 (20.09/ 8.91)	.............LLFDYAE......HDLWhiiKFH..RAAKA
  127-  160 (59.68/45.34)	VMV...PKGMVKsLLYQILD.GIHYLHSNW...VLH..RDLKP
  165-  198 (34.68/20.78)	VMGegnERGRVK.....IADmGFARLF.NA...PLKplADLDP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.18|      15|      41|     238|     253|       5
---------------------------------------------------------------------------
  238-  253 (25.82/20.40)	PIFHCRQEDIKTSNpY
  280-  294 (29.36/17.59)	PEHHTLTKDFKRSN.Y
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.92|      11|      41|     460|     470|       7
---------------------------------------------------------------------------
  460-  470 (23.06/11.18)	QPGNGMNQQDY
  504-  514 (22.86/11.02)	NPQQGGFQQRY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07837 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PNKRITSEQAMQDPYFSEDPMPTADVFAGCPIPYPKREFLTDEDQDDKGESKRQQQQQQQQANQQAQQNQQQQANHQNQQQNQQQQANQQNQQSQQQQQQQQQQQMQQQQQQQAQSSGMDHSTAKRVRMSGPNGQPGNGMNQQDYQVQQAQQAAAAAAAAQQQQQQQQQQQQQQMMFNNPQQGGFQQRY
326
514










Molecular Recognition Features






MoRF SequenceStartStop




1) GFQQRY
2) MDHSTAKRVRMSG
509
444
514
456