<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07758
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MTTHPVGVSSFPQPPEYARQYTDANVAKKNVLPPPIIPSEFTVFGEEYNFEEEMIRSLQSQKMQQLFSSNGDWRSELKKLNRSTVAAFLDLLDILIRCPNHPERLEKISNLRLLFINMHHLINEYRPVQARDALQSMMKLLIKTIEEVTSRFRTYLAMGHEALNQVIDEVPPILSASPMLNVEDVSGESLEERVGAIEDTISKRRSSYDEARKTIVSRREAWRRDVILCELLDNMGDTDTEKRLSPSTSRLQMEY |
Length | 255 |
Position | Middle |
Organism | Onchocerca ochengi (Filarial nematode worm) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida>
Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Onchocerca.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.475 |
Instability index | 69.23 |
Isoelectric point | 5.53 |
Molecular weight | 29428.25 |
Publications | PubMed=22919073
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 RuleBase:RU364060
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP07758
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 153.86| 51| 136| 34| 93| 1
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34- 93 (79.10/69.98) PPIIPSEFTVFGEEYNFE..EEMI..........RSLQSQKMQQLFSSNGDWRSElkklnrstVaAFLDLLD
171- 233 (74.77/47.71) PPILSASPMLNVEDVSGEslEERVgaiedtiskrRSSYDEARKTIVSRREAWRRD........V.ILCELLD
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