<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07755

Description Uncharacterized protein
SequenceMEEKDATTTDCRKTSSAQSGYRKRVMRRVNEDSHTQEPVASGTSNWLSGEERSRLEAVQRDWRLSRPAKPYSPWSRYRQLSIDKSSKSPGTIARKDTTAHQQTLFERNRIPAAPSLVISDTEGNKKKKIHETVNEEDEKEKIEENSAVILEIPLPLPSYESEKKDEELARTEEKQREVVDDDVDAEEEKPIDKSPDGRFLKFDEELGRGSFKTVYRGLDTETGVAVAWCELQESKLNKAERQRFREEAEMLKGLQHPNIVRFYDYWERQDHAGKKRYIVLVTELMTSGTLKMYLKRFKRINIKVLKSWCRQILKGLSFLHSRNPPVIHRDLKCDNIFITGTTGSVKIGDLGLATLKNKSYAKSVIGTPEFMAPEMYEEMYDESVDVYAFGMCLLEMVTGEYPYSECQFPAQIYRKVTTVSFSHRDMFINRDFTALGVKPECFSRIPQQYPEIREIIDRCIRVRREERSTVKQLLSDDFFTPEELIGIRVEIKNRDADLCDVNSEIQMQLRVFDEKKRKQYRFKENEGLQFAFDIETDKAEEVVQQMIEQQHIPEEDTRMITKLIKDKVEAFKRDREFRHAELKRLREEEQRKQEEEAIRNEMLLRAKEKERLEREAAAVLEQQQQSQQQAQQSQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSQQLQQQQQSAGASPENDDHHDGPVKHKKSKKKVAIEVLRVVTDETNQQPLVSCRLDTSHKTVTFQFAPDSDKPSVITKKLLDQDCLTNSQVGVVSEQLEKIIQMIVADPVKAVGVKIVSFVDSASTSANIEMTVSHSNVSANPVASSGVSGESNVMLAATSSMQNFQAVQPPVAPKNQSLDQTTVNSGVPQPAIAPSVAVSKSVVTTQNLPGIVQLPVSVVSHTASSNTTTTTGITTPVPAPAVTTSTTKTSRFLVTKSTLPVDISSSSTLPSLSSNLQEHIAKDAPSVVTAVSNSTSAPLINPVNTSSAVLQQTPNAELRTTLKKLESELCKVSGVNAPSNIPSVMNSGSVPPLDLPAISGGSLPCTSLPHTPSISSGLTHNLTGLNDKLLALSQKMQNEQMEEVVHHGNEAVASVAQTQHSPGITPGLHNASITPVVPTTLPNIVSGTVTPGKASATPEAGILHVDTLNELADALQKVIHFEPRETGSVPPPGVDITGHIAPLSIEHQSSSTTGVLHAGVTNLQDISSEVDRKAANDATKHASEDVKNIGSAGEGSGGENEKSEDGNYPGVASPTFTNNDEATANVHISATIPDGVGGSTANSAPLAKLENLETALTTTLGTHGYCPTVPHIINSTQPNCRTNNVANIDTQQAGLTQVSSLDAIHISQQSFNTMSEACETTQRSTSELAAMAAPKGAVFHVGTPPPPTHFSDSASQTELISTRDPLDHMFSPTTSYNSDYDFQERQRGRNLLVDEDKRIMLQLREILQLDEEYNEEDDDSIQSLIQRHRLELELLRERQRRELQLARLRLRHNQPGVGNTLVATGGGCLTRSIDSCGSGPHDPIHIPYHSLASSRINPHLKLPLSISLPGSPPQNSFLGQHLESLRDTLPRRSYMITSLAECARHTSVDAALSRRPAYPSTHCSSQINSNVADQHRHHQHHHHHYHHHHHQQQQQQQQQQQQQQGSISSSSLDHGYFHGGILSRQPVSTVIHRTSTITEVAPSLNYNIERQLRETFSTPPQ
Length1717
PositionTail
OrganismOnchocerca ochengi (Filarial nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Onchocerca.
Aromaticity0.04
Grand average of hydropathy-0.710
Instability index62.18
Isoelectric point6.05
Molecular weight191372.14
Publications
PubMed=22919073

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
protein serine kinase activity	GO:0106310	IEA:UniProtKB-EC
protein threonine kinase activity	GO:0106311	IEA:UniProtKB-EC

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07755
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     177.74|      15|      15|     634|     648|       1
---------------------------------------------------------------------------
  631-  646 (34.26/12.74)	QQsQQQQQQQQQQQQQ
  647-  662 (34.26/12.74)	QQqQQQQQQQQQQQQQ
  663-  677 (38.66/15.11)	QQ.QQQQQQQQQQQQQ
  678-  692 (38.66/15.11)	QQ.QQQQQQQQQQQQQ
 1647- 1660 (31.89/11.46)	QQ.QQQQQQQQQQQQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.84|      21|      32|     801|     821|       2
---------------------------------------------------------------------------
  805-  838 (26.44/10.98)	KAVGVKIVSFVDSASTSaniemtvshsnvsANPV
  839-  867 (25.39/10.29)	ASSGVSGESNVMLAATS.....smqnfqavQPPV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     118.30|      28|      32|    1094|    1125|       3
---------------------------------------------------------------------------
 1094- 1125 (44.08/31.83)	NE...QMEEVVHHGNEAVASVAqtqhSPGITPG..........LH
 1126- 1160 (32.37/14.34)	NA...SITPVVPTTLPNIVS.......GTVTPGkasatpeagiLH
 1165- 1195 (41.85/20.77)	NEladALQKVIHFEPRETGSVP....PPGVDIT..........GH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.27|      25|      32|      19|      50|       4
---------------------------------------------------------------------------
   23-   48 (40.55/49.47)	KRVMRRVNEDSHTQEPvASGTSNW.....LS
   52-   81 (40.72/20.73)	RSRLEAVQRDWRLSRP.AKPYSPWsryrqLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.80|      16|      31|    1380|    1408|       5
---------------------------------------------------------------------------
 1380- 1407 (23.22/38.78)	STSELaamaapkgavfhVGTPPPPTH.FS
 1411- 1427 (25.58/ 9.20)	SQTEL............ISTRDPLDHmFS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      95.33|      18|      32|    1038|    1055|       6
---------------------------------------------------------------------------
  890-  908 (21.84/ 9.00)	PSVAVSKSVvTTQNLPGIV
  918-  935 (22.19/ 9.27)	TASSNTTTT.TGITTPVPA
  985-  997 (19.20/ 6.97)	TAVSNSTSA......PLIN
 1038- 1055 (32.10/16.88)	PSVMNSGSV.PPLDLPAIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.62|      26|      32|    1433|    1461|       8
---------------------------------------------------------------------------
 1433- 1459 (40.65/34.49)	NSDYDfQE..........RQRGRNLLVDEDKRIMLQL
 1466- 1501 (35.96/18.10)	DEEYN.EEdddsiqsliqRHRLELELLRERQRRELQL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.90|      20|      32|    1298|    1328|      11
---------------------------------------------------------------------------
 1298- 1317 (31.54/48.11)	NSA.PLAKLENLETALTTTLG
 1330- 1350 (31.36/13.71)	NSTqPNCRTNNVANIDTQQAG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.39|      19|      50|     121|     139|      12
---------------------------------------------------------------------------
  121-  139 (31.17/21.47)	TEGNKKKKIHETVNEEDEK
  171-  189 (30.23/20.58)	TEEKQREVVDDDVDAEEEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      81.96|      19|      50|     964|     982|      13
---------------------------------------------------------------------------
  964-  982 (30.08/18.24)	TLPSLSSNLQEHIAKDAPS
  998- 1016 (24.36/13.14)	PVNTSSAVLQQTPNAELRT
 1017- 1035 (27.53/15.96)	TLKKLESELCKVSGVNAPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.20|      32|      48|     365|     402|      14
---------------------------------------------------------------------------
  365-  402 (51.04/47.34)	IGTPEFMAPEMYEEMydesvDVYAFGM...ClLEMVTGEYP
  416-  450 (54.16/33.67)	VTTVSFSHRDMFINR.....DFTALGVkpeC.FSRIPQQYP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.15|      18|      50|     226|     245|      15
---------------------------------------------------------------------------
  235-  267 (19.66/11.95)	KLNKAERQRFreeaemlkglqhpniVRFYDYWE
  268-  286 (22.49/ 7.64)	RQDHAGKKRY..............iVLVTELMT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      48.50|      10|      19|    1239|    1248|      23
---------------------------------------------------------------------------
 1239- 1248 (16.09/ 9.79)	SEDVKNIGSA
 1259- 1268 (16.96/10.79)	SEDGNYPGVA
 1269- 1278 (15.45/ 9.05)	SPTFTNNDEA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07755 with Med15 domain of Kingdom Metazoa
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