<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07752

Description Uncharacterized protein
SequenceMIDYQFKEELIKTRERVEDLYSFEGFKVGRGTYGHVYKAQPRHPEQSSENGAKEFALKLIEGQGFSMSACREIALLRELKHPNLIKLQRVFLTTDRKVWLLFDYAEHDLWHIIKFHRAAKQKKQPVLVPKGMVKSLLYQILDGIHYLHSNWILHRDLKPANILVMGEGPGVERGRVKIGDMGFARIFHNPLKPLAELDPVVVTFWYRAPELLLGAKHYTKAIDIWAIGCIFAELLTSEPVFFCREEDIKASSPYHQDQLNRIFTVMGYPSESDWQDLKKMPEYQKLTQDFKRANYANCTLQRYMDKHKIKADTRSFSLLQRLLTMDPIKRVTAQDAMDDPYFKEDPRPTTDVFSGCDIPYPKREFLSDENDDKSASASKPQQVQPPQQSQQQPVGMHPQQSVMEPAAKKIRMQQGPQMPATQQMEPIMNAPTNGMFAASGTQDYPAVGSGPAISNKGGITFEQHSQQMIQSQHINSSIQQMPYGHQQQHQVINQGPNMYQQQQIGINQQLGGPSQGQIAQRPVQMSTQSSVMQSSYQQQMVQSGMISSQQIMNNGSGMLGQQSGITGPQNQMGPPQGQMGPQGPTIMQQMRSQMSYVDQNGRVIQGGGIIMQPGQEMMQQQGPYMIQQQQWSQIQPRY
Length638
PositionKinase
OrganismOnchocerca ochengi (Filarial nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Onchocerca.
Aromaticity0.08
Grand average of hydropathy-0.647
Instability index56.54
Isoelectric point8.76
Molecular weight72578.04
Publications
PubMed=22919073

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07752
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     393.00|      77|      77|     474|     550|       1
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  381-  454 (92.28/32.58)	.QQVQPPQQSQ...QQPVGMHPQQSVMEPAAKKI...RMQQGpqMPATQQMepimNAPTNG.MfaASG.TQDYPAVGSGPA......IS.
  455-  506 (98.42/35.19)	NK..GGIT...FE.QHS...............QQ...MIQS.......QHI....NSSIQQ.M..PYGHQQQHQVINQGPNMYQQQQIGI
  507-  565 (109.61/39.95)	NQQLGGPSQGQIA.QRPVQMSTQSSVMQSSYQQQ...MVQSG..MISSQ........................QIMNNGSGMLGQQS.GI
  568-  630 (92.69/32.75)	PQNQMGPPQGQMGpQGPTIMQQMRSQM..SYVDQngrVIQGG..GI...............iM..QPGQEMMQQ...QGPYMIQQQQ...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.73|      16|      26|     246|     263|       3
---------------------------------------------------------------------------
  246-  263 (23.01/15.56)	EDIKASSPYhqDQLNRIF
  275-  290 (28.72/13.27)	QDLKKMPEY..QKLTQDF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      65.21|      14|      16|     300|     313|       4
---------------------------------------------------------------------------
  300-  313 (25.17/19.83)	LQRYMDKHKIKADT
  319-  332 (22.11/16.38)	LQRLLTMDPIKRVT
  333-  345 (17.93/11.65)	AQDAMDDPYFKED.
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07752 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AQDAMDDPYFKEDPRPTTDVFSGCDIPYPKREFLSDENDDKSASASKPQQVQPPQQSQQQPVGMHPQQSVMEPAAKKIRMQQGPQMPATQQMEPIMNAPTNGMFAASGTQDYPAVGSGPAISNKGGITFEQHSQQMIQSQHINSSIQQMPYGHQQQHQVINQGPNMYQQQQIGINQQLGGPSQGQIAQRPVQMSTQSSVMQS
2) SGMISSQQIMNNGSGMLGQQSGITGPQNQMGPPQGQMGPQGPTIMQQMRSQMSYVD
333
543
534
598










Molecular Recognition Features






MoRF SequenceStartStop




1) AAKKIRM
406
412