<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07751

Description Uncharacterized protein
SequenceMGRSIKASKRMQSGQSEGEVLDWTVRSEQWGGGVDGGVWMRVAMPDCAALHLVLCGVGSGNACMHPHPCLAACLPRKRQEAAAVLISVATGNARSSATTVPAAKKRCMQQQQHPAVASSSGLSSVVPTVESTTVTVVDRLKHQLLQAYDNGDTEQATDVIIKLEKSNLTKELLEMTRIGAVVNDIRKKVAQSAPELSKRCRTLIKCWQKLAEPRPTSSGSSSTNGTPSYASPAVRKGLTPGTPARCPRVISGGNSRLTPARNSHLASLGSSVLTPSGSSGNITLWMMTASVTGSQSTVTSPTVPNGHTITSYQNSGHEMSMNIAESRTIRKSHTVSADLTIKAVENSLLSGGEIIRNGKRKDENTAISDIGITNGLSAKRPHYSSASVSPTTPHQSLLAAQRADVKSTSELVAQLTENLPGYLAINIPQNQVPARNEHNNNEGQASDANQTLKTPILFTLQPENSKKKEKRGRFKKDKDKKEGRIKDHSVAYGKIIGADNEKASTSAIGNAESELRRNISNNDPSTNKVMVPTRNGKYDWYAMLPSLETLRNREHFRSKPSSNQRKSYIMNVMGREVLALPYIDVGLPDFLEYQYPKPERFYAKENFIYGAPRPN
Length615
PositionUnknown
OrganismOnchocerca ochengi (Filarial nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Onchocerca.
Aromaticity0.04
Grand average of hydropathy-0.548
Instability index47.85
Isoelectric point9.68
Molecular weight66662.68
Publications
PubMed=22919073

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07751
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     121.91|      25|      25|     251|     275|       1
---------------------------------------------------------------------------
  217-  243 (37.99/20.42)	SSGSSSTngTPSYASPAVRKGLTPGTP
  251-  275 (42.53/23.74)	SGGNSRL..TPARNSHLASLGSSVLTP
  278-  301 (41.39/22.91)	SSGNITL..WMMTASVTGS.QSTVTSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     264.06|      86|     253|      76|     163|       2
---------------------------------------------------------------------------
   76-  163 (131.79/74.80)	RKRQEAAAVLISVATGNARSSATTVPAAKKRCMQQQQHPAVASSSGLSSVVPTVESTTVTVVDRlkHQLLQAYDNGDTEQATDVIIKL
  330-  415 (132.28/70.49)	RKSHTVSADLTIKAVENSLLSGGEIIRNGKRKDENTAISDIGITNGLSAKRPHYSSASVSPTTP..HQSLLAAQRADVKSTSELVAQL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07751 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AEPRPTSSGSSSTNGTPSYASPAVRKGLTPGTPARCPRVISGGNSRLTPARNSHLASLGSSV
2) ASTSAIGNAESELRRNISNNDPSTNKVMVP
3) GSQSTVTSPTVPNGHTITSYQNSGHEMSMNIAESRTIRKS
4) YLAINIPQNQVPARNEHNNNEGQASDANQTLKTPILFTLQPENSKKKEKRGRFKKDKDKKEGRIKDHSVA
211
503
293
422
272
532
332
491










Molecular Recognition Features






MoRF SequenceStartStop




1) GKYDWYAM
2) KENFIYGAP
536
604
543
612