<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07749

Description Uncharacterized protein
SequenceMNISDWAKPEVVQLLEQYIQEPARSIEELQKLIQQIAGKNVTVSKLRHHLQQFQKETVVYKQHSKDVVFNENEKSTTEIKQCNSRRTAAENRVSVEVIPTDSTNFEQGIQMAREISINKQEKISNSREQIDHVPDNAKAASIRTRTLRKKLRVSTWRKKELQMLRSSRSRRRKKMKNGSSTTTIIDRGKNLKATTDDKSVKQKAEEQEMNSTIKAAGTIVPSTELTVLISSKPRVILRRTTLVRTRCTVLATKPTIPISVVTSYSQQIPDWNVHENDDVTELTIPNSNTDAVTSYSQGIFGGNVRGNHGNDDITLLWQPVTYSSIGLESNPTGVYIDSSCSSGSEMQGNLSSQQFQSLTTHLDHCLNALRLLRNEVTSVHRRIMENNWESDPADSEKTLEEKLDFINQIYDNLESHAKQLPLSTPMTVQMERLSRFLHDGQIDPHTSELYDKALEASTWMETNNQLLQMYAEFLRTVVGNRRRSIMTDRPISYSNYGPNSSPQSIFEQTLTVVLKDPNIKKIGLVGRYLEKSTLSALVEFKFGQVIDKQYVCLLKMLMVVNSGLPEFVQMIAPHEEWSYLDVGSGQVDIHKESRYLVYRKMSVQANIHLMQTIMPCIDIRNAHTLSYVLNLFAKFSGVFDIKCRVCKKIMKDYLPPLMFDLRCPKNALHESCR
Length673
PositionTail
OrganismOnchocerca ochengi (Filarial nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Onchocerca.
Aromaticity0.06
Grand average of hydropathy-0.516
Instability index47.54
Isoelectric point9.01
Molecular weight76861.85
Publications
PubMed=22919073

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP07749
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.44|      29|      33|     248|     280|       1
---------------------------------------------------------------------------
  248-  280 (51.53/39.15)	TVlatkPTIPISVVTSYSQQIPDWNV...HENDDVT
  283-  314 (50.91/30.15)	TI....PNSNTDAVTSYSQGIFGGNVrgnHGNDDIT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.19|      17|      32|     157|     173|       2
---------------------------------------------------------------------------
  157-  173 (28.53/19.79)	RKKELQMLRSSRSRRRK
  187-  203 (25.66/17.04)	RGKNLKATTDDKSVKQK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.72|      20|      33|     401|     426|       3
---------------------------------------------------------------------------
  401-  426 (32.59/43.28)	EKLD.FIN..QI.......YDnleshaKQLPLSTPM
  431-  460 (23.13/15.69)	ERLSrFLHdgQIdphtselYD......KALEASTWM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.68|      30|      33|      69|      99|       5
---------------------------------------------------------------------------
   69-   99 (44.20/37.74)	FNENEKSTTEIkQCNSRRTAAENRVSVEVIP
  105-  134 (49.48/37.09)	FEQGIQMAREI.SINKQEKISNSREQIDHVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.73|      14|     299|      44|      57|       6
---------------------------------------------------------------------------
   27-   41 (15.79/ 6.66)	EELQKLIQQIAgKNV
   44-   57 (23.93/13.14)	SKLRHHLQQFQ.KET
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP07749 with Med27 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) GIQMAREISINKQEKISNSREQIDHVPDNAKAASIRT
2) KKELQMLRSSRSRRRKKMKNGSSTTTIIDRGKNLKATTDDKSVKQKAEEQEMNSTIKAA
108
158
144
216

Molecular Recognition Features

MoRF SequenceStartStop
NANANA