<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07746

Description Uncharacterized protein
SequenceMPHPHNPINPSRAAQAQSDNQHSATSANEQGSSALTIYQLKPPEWRLPTQLNRPELGYPGLHPTHPGQHEDAITKSLVQWGFSAQMLVSTESFSAHQMIYKKITDEATFNVSSSALSALIEARRRDYAISSYDTESTIKVPGRVTLNEQKRENWLRELADNSVPLLKLSKNVPHGFKGEKLLEMLVTRKIDSTRATWYIRLIGLNEINAQRNKNELSHIRYTLSFTSDVCQFLYKQLSEVTVPLQMNLSSSTTSLITTSSRLAAMNVRSKPRSSTLSDPETRKHWVAKWNQSRMLLKRLYFESLLDQPTFFKWLIDQLKTANLAQINFLLEIHHSVLERFSLSSNLVRGFVEACLSQIRFIAKQTSTLFLSKLERRLKLAVQSAFIFSPDNFVWPDIWISNKVLLEDIILANSSPSSETHQLREMLKGDFYAVNWRISELIGEVGIGTGVVVNIFTRRAQLVEILDSYTDYNDCSKLYYKYFLNPSVAGHISVSFKDRLEVLLSWATTFLRASDKRVHLVASTLSCVKHDYKKNADEFQNILVGWLEQIESIEGGDLLVRLFSELSRRNIFSYGAYVQRMVAKGDTECDIVPGKASGLQALLSEWMPLASSKASRERSSSIKRSPGRDSARNGLMAIIADFNSAIASADYGRFTSLLKRRLDVRQPSSANRKLLAEILPNALVNLVSELAFPNLSGSGFLVGKAPNHPQMASALLTWAIQLIEACQAYTALFEIMQRIVQIDLSRLEALRGDERACADLKILEINGQLADLISRLFAIYVHFRRLIGGTFPVVRGFVRYLRNLVIESNAVDGQILEVLHKEYHPVSDEMMTAPPGGETLPSRTREILQLIQSPSTDQASQLVLKYWQEYRSDMDWGPVLWNSLIAALKIYSQEEFEEPLSQNTGDSAQVTSKNWGHFREVIMQFCEDLDVLYEEGLIGCLMRAGHTNYPHSDDEGLFSQPVDKSDVKMTSEEEEGEEGEEIAAEGPSLKSLFFHNPRSLCRNIRRLIIELMSCGLISIEVGLEEYAIRPLADDIPQLLVNLCGDNSSDFHRAPQTTQAEEALRQVKQIYELVNEALSEQHTDRCSPVSHSPDKEFAVMMTPSHSRSEGHQSFTNQGTPEVSFKSKDVEHAIEEYVRTWKLSVERKLWFEQSDEGSAFCSRLLLSLLISIKTVSELSLDPEAPENPAGQQRESFAQLIARILDVFESLRGTVCRGSNLLRRQIPAQSAVFLNPMLDFVSKNDLGTIFHTKLIHSIDELLPYSQPTDLVNQKYPYLESIFKATCIFNYAARTRQFQLHIRVLMSKNPPQMTTNKEAPLDLTSTLGALVETMAKRLHLTDSKDASPFFLDCLPEQVAEALILKLSLYLGMSICKLLSPNNTDSALEILRIHHICRCITTLTNQLTVRTYQPNGDAMIKVVGGCGPLGCNATVESYMSYWQQLKSGLSLLNTRLTASEPSGLNPKRMEYRIMRALLHSIQVVLWSLPGLTQHLGTLKQTIAEIWIEIALRVQGDSALQNQIMDTISILLFPTVPDDSCLTATMGILRKRFRWLYLPILNLDDGANLVPSNRLKYLLGSSLRGSSTIFQERLGDGAVKFVEEKPWEELEKMDLSGPGFISIDALKCQTLSHVEQIPEPKRLISRQPKSKRGNAEGEETRAEEIEIGGERSSDQQMGGAHGSEGEEEEAPIRGERLCFEHELITDGLSTMPLHFLRSLFPPASRLSGEDLLVAQEQQKLVQAHQAEQTRLQQQQASIGAVAEQDSSRTKKRKGLGLSPLAVDQSSSSNTGPTLRSARSTRKKSSAAAPVNPPTTSGSKRAKRR
Length1817
PositionKinase
OrganismPuccinia triticina (isolate 1-1 / race 1 (BBBD)) (Brown leaf rust fungus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Pucciniomycotina> Pucciniomycetes> Pucciniales> Pucciniaceae> Puccinia.
Aromaticity0.07
Grand average of hydropathy-0.280
Instability index52.48
Isoelectric point6.50
Molecular weight204011.36
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07746
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     219.89|      67|     279|     864|     931|       1
---------------------------------------------------------------------------
  864-  931 (117.57/77.62)	KYWQEyRSDMD..WGPVLWNSLIAALKIYSQ.....EEFEEPLSQNTGDSAQVTSKNWGHFREVIMQFCEDLDVL
 1145- 1218 (102.31/62.38)	KLWFE.QSDEGsaFCSRLLLSLLISIKTVSElsldpEAPENPAGQQRESFAQLIARILDVFESLRGTVCRGSNLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     166.80|      56|     429|     547|     634|       2
---------------------------------------------------------------------------
  548-  607 (89.89/112.98)	QIESIEG..GDLLVRLFSELS..RRNIfsYGAY..VQ...RMVAKGDTECDIVPGKAsgLQALLSEWMP
  760-  824 (76.92/36.57)	KILEINGqlADLISRLFAIYVhfRRLI..GGTFpvVRgfvRYLRNLVIESNAVDGQI..LEVLHKEYHP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.54|      19|     429|      89|     111|       3
---------------------------------------------------------------------------
   89-  111 (26.23/27.56)	STESFSAHQmiYKKITDEatF.NV
  522-  541 (32.31/19.08)	STLSCVKHD..YKKNADE..FqNI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     113.25|      27|      29|    1556|    1582|       4
---------------------------------------------------------------------------
  684-  700 (23.76/10.64)	......NLV.....SELAFPNLSGSGFL
 1556- 1582 (44.54/27.11)	LDDGA.NLVPSNRLKYLLGSSLRGSSTI
 1587- 1614 (44.95/27.43)	LGDGAvKFVEEKPWEELEKMDLSGPGFI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     230.80|      74|     690|     975|    1061|       6
---------------------------------------------------------------------------
  975- 1061 (106.36/107.10)	GEEGEEiaAEGPslkslfFHNPRsLCRNiRRLIIELMSCGLISIEVGLEEYAIRPLADDipqLLVNLCGDNSSDFHRAPQT.TQAEEA
 1675- 1749 (124.45/84.67)	GSEGEE..EEAP......IRGER.LCFE.HELITDGLSTMPLHFLRSLFPPASRLSGED...LLVAQEQQKLVQAHQAEQTrLQQQQA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.08|      18|     788|     655|     672|       7
---------------------------------------------------------------------------
  655-  672 (31.30/16.24)	SLLKRRLDVRQPSSANRK
 1444- 1461 (31.77/16.59)	SLLNTRLTASEPSGLNPK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.68|      23|     692|     705|     731|      14
---------------------------------------------------------------------------
  705-  731 (34.21/37.67)	PNHPQmaSALLTWAIQLIeaCQAYTAL
 1375- 1397 (43.48/31.11)	PNNTD..SALEILRIHHI..CRCITTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.15|      18|     300|     945|     962|      17
---------------------------------------------------------------------------
  945-  962 (37.56/29.28)	HTNYPHSDDEGL.FSQPVD
 1247- 1265 (30.59/22.17)	HTKLIHSIDELLpYSQPTD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.16|      24|    1157|     608|     631|      18
---------------------------------------------------------------------------
  608-  631 (39.64/18.30)	LASSKASRERSSSIKRSPGRDSAR
 1768- 1791 (40.52/18.85)	LGLSPLAVDQSSSSNTGPTLRSAR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07746 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IPEPKRLISRQPKSKRGNAEGEETRAEEIEIGGERSSDQQMGGAHGSEGEEEEAPIRGER
2) LSGEDLLVAQEQQKLVQAHQAEQTRLQQQQASIGAVAEQDSSRTKKRKGLGLSPLAVDQSSSSNTGPTLRSARSTRKKSSAAAPVNPPTTSGSKRAKRR
3) MPHPHNPINPSRAAQAQSDNQHSATSANEQGSSAL
4) VSHSPDKEFAVMMTPSHSRSEGHQSFTNQGTPE
1630
1719
1
1087
1689
1817
35
1119










Molecular Recognition Features






MoRF SequenceStartStop




1) SKRAKRR
1811
1817