<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07734

Description Mediator of RNA polymerase II transcription subunit 5
SequenceMIVNSKGQLGCLIFEVALGFRVGQTAEVRPSHLGIPSLKDQTIRLPPDKPHSQHKKPPATKLVIQFDLLSIHQLWLALNAKFDAQSRLLNYKPSGPPLPILFHHPKKTKPSLEELSATVLKSPRKSAYCAHPSLPCSTRPSSPHHHHHQPSPKTQSQPQKSSRTGPVALLASLISNYLVQPQDLPEQDGQSGSHVNLDLGLQPLLDCLGKEMTELAVALQQRATKTFDLSTCIALSNAPSVLDVLSTLFLWLEPRTILIPFRGLLNHWITIRNNLSQITASGPDGNKAGSGSGFKNFGGLLGWIQGRFSGSSGIPDALLSTTNPRIFFAIALSLFKQSFNALNVCLINLQTFRDGLSYFEHKLLIARAAVGMLDKLSRLGPISSNLYPTNLLEILKAILLLDAISATGLQLVATHLQSVVCVFAKRTWRMPAALSRLGADLNWRVQLDVDAIKQRLMVLPAAEMLAPVWWPKR
Length473
PositionTail
OrganismPuccinia triticina (isolate 1-1 / race 1 (BBBD)) (Brown leaf rust fungus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Pucciniomycotina> Pucciniomycetes> Pucciniales> Pucciniaceae> Puccinia.
Aromaticity0.07
Grand average of hydropathy-0.006
Instability index44.61
Isoelectric point9.79
Molecular weight51908.86
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07734
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.86|      30|      34|      96|     126|       1
---------------------------------------------------------------------------
   96-  126 (48.10/26.74)	PPLPIlFHHPKKTKPSLEELSATVLKSPRKS
  132-  161 (58.75/29.65)	PSLPC.STRPSSPHHHHHQPSPKTQSQPQKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.60|      11|      33|     261|     272|       2
---------------------------------------------------------------------------
  261-  272 (18.13/15.24)	FRGLLNhWITIR
  297-  307 (23.48/13.88)	FGGLLG.WIQGR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      72.13|      15|      57|     366|     380|       3
---------------------------------------------------------------------------
  366-  380 (24.85/17.25)	ARAAVGMLDKLSRLG
  394-  408 (20.79/13.17)	ILKAILLLDAISATG
  424-  438 (26.49/18.91)	AKRTWRMPAALSRLG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07734 with Med5 domain of Kingdom Fungi
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