<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07663
Description |
Mediator of RNA polymerase II transcription subunit 6 |
Sequence | MPPQIPLLDEQEFDQPALIGGVPNQDLNYGNNPFYYFTSSPWFEPMSINVSVLNNLALDANGQQVMNDRKLWDERLRRETQGTQFMIVGEPQADGQPWVLQRHNKVRADDGKKIDTHVEGTWYFQGTRVLMAPSLLDVVQSRLLSVATRMQQLAEISKGMTHWTPATGYSYFAPSHADDAAKAASSRIGSPTLAPTDPDAATSTSQSQGAAATSAQANDPLASTTDFSDALFLQSLAMTNAYGDEFMDENPLKGEPGAFVFENTRSAVETRNKAQQEQAASQASSSSQPTTTTTTTAVAGVPLKLETQPPSVVPSAVGTPRGIATPGGVEAHSRKNSVAAVPLKKGKKDRRKSQGGLASPVTPMGP |
Length | 366 |
Position | Head |
Organism | Pyrenochaeta sp. DS3sAY3a |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes>
Pleosporomycetidae> Pleosporales> Pleosporineae> Cucurbitariaceae>
Pyrenochaeta> unclassified Pyrenochaeta.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.504 |
Instability index | 43.74 |
Isoelectric point | 5.47 |
Molecular weight | 39275.28 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364143
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP07663
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 264.70| 66| 72| 220| 291| 1
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144- 209 (76.28/44.41) .......LSVATRMQQL...AeiskgMTHwtpATGYSYF..APSHADDAA...KAASSRIGSPTLAPTDPDA..ATSTSQSQG
220- 291 (104.06/77.25) PlasttdFSDALFLQSL...A.....MTN...AYGDEFMDENPLKGEPGAFVFENTRSAVETRNKAQQEQAASQASSSSQPTT
302- 362 (84.36/51.79) P..........LKLETQppsV.....VPS...AVGTPRGIATP..GGVEAHSRKNSVAAVPLK.KGKKDRRKSQGGLAS.PVT
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