<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07651
Description |
Mediator of RNA polymerase II transcription subunit 20 |
Sequence | MKYSGLYLIPNPTTTLDTAIALVSTLVQNLETTYPTATRHSPWTLSYRVFRDTIPRDHTPSADADGKPRPFPHTYQSILHHSTYSPSRAYICTQPPGDPGRGTVAAIPLRQQDAYAALVRYQEAALWAPRHVLSVTGGTTYTVGLCTIQIAELRATREGPQSAAVQSPGVVVSISVEIGGGEDADESTANGRAGSGALGNGVEDAEDEAMQVEYAQAVIREAWGKVKEGKDLGRSEIKEVMMKLGRETETKETDAAVRMWCEVLRLRG |
Length | 268 |
Position | Head |
Organism | Pyrenochaeta sp. DS3sAY3a |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes>
Pleosporomycetidae> Pleosporales> Pleosporineae> Cucurbitariaceae>
Pyrenochaeta> unclassified Pyrenochaeta.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.379 |
Instability index | 34.96 |
Isoelectric point | 5.73 |
Molecular weight | 29072.31 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364152
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP07651
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 56.67| 17| 39| 122| 138| 1
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122- 138 (32.11/18.09) QEAALWAPRHVLSVT...GG
161- 180 (24.56/12.52) QSAAVQSPGVVVSISveiGG
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 80.94| 22| 38| 33| 55| 2
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33- 55 (38.24/31.42) TYPTATRHSPWTLSyRVFRDTIP
74- 95 (42.70/29.27) TYQSILHHSTYSPS.RAYICTQP
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