<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07641
Description |
Mediator of RNA polymerase II transcription subunit 17 |
Sequence | MPGAESLTNVTLRPWPTSKKEELGSQDLLQQVEQLANERGHLRNVTEKSLREDIAAGIDASVETTSDSEGKKDKKDAPSKEERLQDVFRMQQEMSSHMEWAKFAANNAVDLISLVLSADPNKRSVASFSHTFRTEGLSQGIPFGSFGVSKENHDQHVRKPDELQSLQEYEQRQELVSKGSRMAALDTATDDILKAAKQFEKEVRRETKYWQEIVSISDKGWPIQRVRQNARNVPFAVRYGLPEASDHFKARGLAPLRKDKDGSIILDPALALKPKTLRVRISHNGKITGMSHLPVDGAENDSSIEKTIQLARDSLFEEELFHEMRLETRQLLPYGVEYRDSVIHVKAADAKESNREKKLLIDCIARDDHSFNYQDHSGDWLAQDVAEGLRLLLAHEHSMRLYRRSQLPPPLTGQEREAPSPPLLRTLLAVFHHIEGVDALYEHLGQVTKTLSSAGLSVHLETTRESSWASFAKSLQSSQKKRMSATDQLLEMFAKPFEGKAILAISPSSGAQQDNLTIATRTVIGQPTFGTEHKLILPSALVADLGLFQQLKFTSVEETTSYLDWILSLHVAHRCLKGDFPRALIKENDARLIIRSKDAKKEATVDQDISVELQNGELKLTTKTVSGASEDAVQSYVWKGQEGEVALVDKVKSWVG |
Length | 656 |
Position | Head |
Organism | Stagonospora sp. SRC1lsM3a |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes>
Pleosporomycetidae> Pleosporales> Massarineae> Massarinaceae> Stagonospora>
unclassified Stagonospora.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.541 |
Instability index | 43.76 |
Isoelectric point | 6.20 |
Molecular weight | 73458.04 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP07641
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 47.20| 12| 72| 322| 333| 1
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322- 333 (23.16/17.86) HEMRLETRQLLP
397- 408 (24.04/18.84) HSMRLYRRSQLP
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 73.38| 21| 70| 79| 100| 2
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79- 100 (35.09/24.92) SKEERLQDVfRMQQEMSSHMEW
149- 169 (38.30/22.26) SKENHDQHV.RKPDELQSLQEY
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 107.63| 35| 392| 16| 68| 4
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30- 68 (48.09/36.04) QQVEQLANERGHLRNVTeKSLRediAAGIDASVETTSDS
432- 466 (59.54/49.98) HHIEGVDALYEHLGQVT.KTLS...SAGLSVHLETTRES
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 66.63| 21| 36| 301| 321| 6
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301- 321 (33.68/25.93) DSSIEKTIQLARDSLFEEELF
340- 360 (32.95/25.19) DSVIHVKAADAKESNREKKLL
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