Description | Mediator of RNA polymerase II transcription subunit 20 |
Sequence | MKYSGLYHISNPSTSLDASLSIVTNLVQGIESNFHTATRQSTWTLQYRLFRDTIPPRHTPATDAEGKSIPFTHTLQHLLHLSSIDQNRTYTCVQPPNGSSTVSAIPLRQQEAHALLLRNQFSALWQPRHVLSVQQGTTYAAGLCTIQIGELRSSREGLQSQAGGIQSPGVLVCISAIVGSGESEDALDSDDGQDTLDLDCAEALVRDFWNKIRGGRDLGKSEVKEVMMSHNNLKGQEKEAAVRMWCEVLRMRG |
Length | 253 |
Position | Head |
Organism | Stagonospora sp. SRC1lsM3a |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes> Pleosporomycetidae> Pleosporales> Massarineae> Massarinaceae> Stagonospora> unclassified Stagonospora. |
Aromaticity | 0.06 |
Grand average of hydropathy | -0.372 |
Instability index | 44.04 |
Isoelectric point | 6.30 |
Molecular weight | 27886.05 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364152 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP07633 No repeats found |
MoRF Sequence | Start | Stop |
1) LDLDCA 2) MKYSGLYHI | 196 1 | 201 9 |
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