<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07607

Description Uncharacterized protein
SequenceMSRIPDSRQRAWQGRSGMGTTGSAGPSSPAVGTQHHHGKERSTEASMSSVATSDDDARKPPQAYTLEPPSFRPYLHPYASGLGTPDFYPATPDLPEFTLNSQVMREGLQSKSQIGSEAFSIHNMIYERLSTPGVLSTLTALLHNVVHLRLPSHGCPPSATASGVSAHSFRLPNRVTLNDLKLGNYIRQLADPSVPLHRLARSVPHGSKGERLLDMLWLGAPPPTQQSSTYSSMGAHGLRIPGAAAATGLGVGAASSAAPVSIPASVPIERAVWFIRVVGASDIQSARNRSTNYTVEWTTTVTAWLQRQLQELGAPPESKAAGASSTARGQTLHNTSPITASVPGALSSPITAAVTSPSSGPSSPVQMRGFSQAGFGRSNFWHSSPGMSSAESATPTSSASLGRTTRTLMQPALLPRWVSKWTYSLSLIRALLHQQLLDTRSFFSWLAESFKSADVTQAAVLLFVVEEALEDMLRPGPTLRTGFPVLKNEARIWWPQLASGLCERLQTFVQQLAALETKSGSITDFLDTLSSREQSDDGSISDIYRFTCTRIRDLIVLAFDLQPSLFLHPGLWANYATLLGQIILADDPNVQRRPSIGRLSKNPLQQRRADYAILQTKCDRLLNGPAFDRIASAEDHTTLDLREMLRTLESCHSATLDFHALFQQFFGMQKQGSRANVMESAAENLYPRVKLLLTWACRTDGERLESLQGGASLQPDPFEHCSVDAHRPFVAIRILTHFAGIDVGIPSLDIKTGDRSGKITYTSVADIHILLMRWLSEVDECQRAAPASVKDTPNKDDSPNLGVSLLFVQFERILTVFTELELLGMFSFSKYIQRMTARGLISRQFPPAQKQVQSTPTQNAPKHSDNTLFGRLLRSLPIHDATEAQLKTRRLAIYGPRDSESREEAMERRALRELRSSFGWLLERRMEREESTIQPGSIGGATTDAKTPEPTSEATYAQQESRARSDDEADEMEALFSDDAESEYDVDVQTSARPAPDLPYFFRCSRFTQRRLLRQIILPCLERHETFPAALATAEQVTELFKLFRATADFANLARIVVAILRSASSVATMRVACNLLVTHVPVWRAIGVLEELLNTIQAASSKISEPEITNMFAFSASLATSPAFDKHVPAVDRATRAFVLTQSAWACVRLGALDLSRFAEAFRDNVSFQSSAESGQSAASWKTYFDDLFQRKGAKSVEASLPLPTLMHDQDPSDAARFLLIGAFRHVRTASVSNAALIVGHLTHFCCSHVMTLDEQASQNGQQLWSIGDIDDATDWPALGQGRVSFRAHQRFLEDLIGNGCVSAEVAIKSMLLPHLKSFASGSSLVDNIVGRTALATALSFIQMSLLPSSAAAQRLARPSSSRMAVERTLLLQPRCVPLLAQVYVSLVWAGKRASRPDISDANPIFSSACASLAKALQADARFRSAIAKDHAAFITACREEMGGIDPSDCSQILFEIANLIGTIDIDPHKDEPGVWRKCLQAFDALTAFRSMAQLALALESATMQGSATSKLLPTLQTIALYSYPSLCLQWSGELAEHAFAAANSSSLLSTLFEAALLRIKSQWSGRSDQKAHLLVGARAIRELLSRSTQFTVQVQCGPITDSLLLLVEERLLQLNQSLLGDDCGASLRDDLSATLAVFRQMIRTSSFWTPITRQKGPRLLKILINLALDVAMDDMLLEDALGSIDLLLSELPSDAPTRAAVNSVLSGYSDNDTTATKDDMFPALPLPGSIESRISQRLPISIPDPVGEGLLFGSTPSSAVFHRRFSLQPNKVWDHLEFIVQPDGGRTSTTSATTPRLDSKPVSDHTDAGSLSKMEAMTGPALVWLNNAGSLSLADFGAKRTRDLITVPADSAGASGELNGPRTRVRELSQDCPVTERTYGDGVGGEPIIARDLQSGAVNPSVEKRARIPMGLKIPSLPLPDEDLTDDPHLGSENESGEDDHGADGTNLQGRSRDSSIRGSVTDRDVTIQGSADLTRSHRKRKRHDKEGGDRDDDGGAASSGLSEAPTPSAEAPATSPAPDDTLTQDFPTRSVSGGPRRGRSVRGRVGRGRK
Length2053
PositionKinase
OrganismTilletia walkeri
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina> Exobasidiomycetes> Tilletiales> Tilletiaceae> Tilletia.
Aromaticity0.06
Grand average of hydropathy-0.234
Instability index47.69
Isoelectric point6.44
Molecular weight223093.45
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07607
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     435.49|     154|     289|     985|    1157|       1
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  985- 1157 (220.68/156.33)	DVDVQTSaRPA.PDLPYFFRC.SRFTQRRL..........LRQIILPCLerhETFPAALATAEQVTELFKLfrATAdfanLARIVVAILRSAS........SVATMRVACNLLVThvPvwRAIGVLEELLNTIQAASSKISEPEITN...MFAFS.ASLATSPAFD.KHVPAVDRATRAFVLtqsawAC.VRLGALDLS
 1270- 1449 (214.81/111.48)	DIDDATD.WPAlGQGRVSFRAhQRFLEDLIgngcvsaevaIKSMLLPHL...KSFASGSSLVDNIVGRTAL..ATA....LSFIQMSLLPSSAaaqrlarpSSSRMAVERTLLLQ..P..RCVPLLAQVYVSLVWAGKRASRPDISDanpIFSSAcASLAKALQADaRFRSAIAKDHAAFIT.....ACrEEMGGIDPS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     203.14|      60|      97|    1893|    1955|       2
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 1893- 1955 (96.71/61.76)	RDLQSGAVNPSVEKrARIPMGLKIPSLPLPDEDLTDDphLGSENESGEDDHGADGTNLQGRSR
 1993- 2052 (106.42/57.53)	RDDDGGAASSGLSE.APTPSAEAPATSPAPDDTLTQD..FPTRSVSGGPRRGRSVRGRVGRGR
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      89.08|      17|      20|     121|     140|       3
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  121-  137 (28.75/ 9.86)	IHNMIYERLSTPGVLST
  142-  158 (32.59/17.36)	LHNVVHLRLPSHGCPPS
  332-  348 (27.74/ 9.08)	LHNTSPITASVPGALSS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     267.92|      86|     289|     539|     657|       4
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  450-  537 (136.47/90.21)	FKSADVTQAAVLLFVVEEALedMLRPG....PTLRTGFPVLKNEARI.WWPQLASGLCERLQTFVQQLAALETKSGSITD..FLDTLSSREQSDD
  546-  638 (131.45/120.19)	FTCTRIRDLIVLAFDLQPSL..FLHPGlwanYATLLGQIILADDPNVqRRPSIGRLSKNPLQQRRADYAILQTKCDRLLNgpAFDRIASAEDHTT
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     321.38|      83|    1378|     359|     449|       5
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  359-  449 (135.91/89.07)	SGPSSPVQMRGFSqagFGRSNFW.HSSPGMSSAESATPTSSASlGRTTrtlmQPALLPRWVSKWT..YSLSLIRALLHQQLLDTRSFFSWL..AES
  926-  982 (73.68/34.58)	.............................MEREESTIQPGSIG.GATT.....DAKTPEPTSEAT..YAQQESRARSDDEADEMEALFSDD..AES
 1756- 1832 (111.79/57.61)	STPSSAVFHRRFS...LQPNKVWdHLEFIVQPDGGRTSTTSAT.........TPRLDSKPVSDHTdaGSLSKMEAMTGPALV.......WLnnAGS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.32|      14|      15|    1220|    1233|       6
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 1220- 1233 (22.93/15.04)	LLIGAFRHVRTASV
 1238- 1251 (27.38/19.55)	LIVGHLTHFCCSHV
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.64|      10|      32|    1531|    1540|       8
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 1531- 1540 (19.72/10.53)	QWSGELAEHA
 1564- 1573 (19.92/10.72)	QWSGRSDQKA
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.93|      24|     294|       9|      32|       9
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    9-   32 (45.48/29.15)	QRAWQGRSGMGTTGSAGPSSPAVG
  306-  329 (41.45/25.72)	QRQLQELGAPPESKAAGASSTARG
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.20|      23|     106|     639|     675|      10
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  649-  674 (34.31/43.58)	ESCHSATlDFHALFQQFFgmQKQGSR
 1174- 1196 (41.89/14.33)	ESGQSAA.SWKTYFDDLF..QRKGAK
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     149.28|      44|     491|     209|     255|      11
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  209-  255 (72.24/41.00)	GERlLDMLWLGA...PPPTQQSSTYSSMGAHGLRIPGAAAatGLGVGAAS
  701-  747 (77.04/35.93)	GER.LESLQGGAslqPDPFEHCSVDAHRPFVAIRILTHFA..GIDVGIPS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.23|      17|      34|    1511|    1527|      13
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 1511- 1527 (30.16/17.50)	SKLLPTLQTIALYSYPS
 1547- 1563 (27.07/14.93)	SSLLSTLFEAALLRIKS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.68|      19|    1298|     278|     296|      14
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  278-  296 (33.31/21.84)	VGASDIQSARNRSTNYTVE
 1577- 1595 (32.37/20.99)	VGARAIRELLSRSTQFTVQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.79|      28|      56|    1597|    1626|      15
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 1597- 1626 (44.61/35.40)	QCGPitDSLLLLVEERL.LQLNQSLLGDDCG
 1656- 1684 (42.18/26.74)	QKGP..RLLKILINLALdVAMDDMLLEDALG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07607 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DGGRTSTTSATTPRLDSKPVSDHTDAGSLSK
2) EESTIQPGSIGGATTDAKTPEPTSEATYAQQESRARSDDEADEMEALF
3) LITVPADSAGASGELNGPRTRVRELSQDCPVTERTYGDGVGGEPIIARDLQSGAVNPSVEKRARIPMGLKIPSLPLPDEDLTDDPHLGSENESGEDDHGADGTNLQGRSRDSSIRGSVTDRDVTIQGSADLTRSHRKRKRHDKEGGDRDDDGGAASSGLSEAPTPSAEAPATSPAPDDTLTQDFPTRSVSGGPRRGRSVRGRVGRGRK
4) MSRIPDSRQRAWQGRSGMGTTGSAGPSSPAVGTQHHHGKERSTEASMSSVATSDDDARKPPQAYTLEPPS
5) QRQLQELGAPPESKAAGASSTARGQTLHNTSPITA
1785
929
1846
1
306
1815
976
2053
70
340










Molecular Recognition Features






MoRF SequenceStartStop




1) AWQGRSGMGTTG
2) TLTQDFPTRSV
3) VRGRVGRGRK
11
2024
2044
22
2034
2053