<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07593

Description Uncharacterized protein
SequenceMLTVVTDNDALNIDADASITVETLKAIIEADTGIPADQQLLIFNTTTVDDPSKTLASYGYTDSDLLLLQQRRPQQQQQQQQQQQQQQQQRSAQAPAAASRSGATPAAAAGPSSRAAPGARPLVPGPGHQNIEAAAETLRLQLLNNPNFLQQIRAARPELADAVSSSPDRFLQLLEAERARTNAAQLDRAQAEHDLANTNEFDIEAQRKIEEAIRQERVMENLEHAMEFSPESFGRVTMLYVESEVNGTAVKAFVDSGAQATIMSPECAERCGIMRLLDTRFAGIARGVGTAKILGRVHSAQLKLGTELFLPCSFTIMEGKGVELLFGLDMLKRFQATIDLASNALIIQGKRVRFLDEHELPDSARMEEPPVDEQGNPLPPV
Length381
PositionTail
OrganismTilletia walkeri
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina> Exobasidiomycetes> Tilletiales> Tilletiaceae> Tilletia.
Aromaticity0.04
Grand average of hydropathy-0.351
Instability index49.82
Isoelectric point4.85
Molecular weight41571.32
Publications









Function






Annotated function

Probable aspartic protease. May be involved in the regulation
of exocytosis. Acts as a linker between the 19S proteasome and
polyubiquitinated proteins via UBA domain interactions with ubiquitin
for their subsequent degradation. Required for S-phase checkpoint
control. 


ECO:0000256	ARBA:ARBA00003231

GO - Cellular Component
GO - Biological Function
aspartic-type endopeptidase activity	GO:0004190	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07593
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.26|      10|      29|     316|     325|       1
---------------------------------------------------------------------------
  316-  325 (17.48/13.87)	IMEGKGVELL
  346-  355 (17.78/14.24)	IIQGKRVRFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.20|      18|      19|     120|     138|       2
---------------------------------------------------------------------------
  121-  138 (32.44/20.60)	PLVPGPGH.QNIEAAAETL
  141-  159 (27.76/11.64)	QLLNNPNFlQQIRAARPEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      51.79|      11|      25|     194|     204|       3
---------------------------------------------------------------------------
  194-  204 (17.52/ 9.35)	DLANTNEFDIE
  210-  220 (15.86/ 7.91)	EEAIRQERVME
  221-  231 (18.40/10.12)	NLEHAMEFSPE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07593 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LLLQQRRPQQQQQQQQQQQQQQQQRSAQAPAAASRSGATPAAAAGPSSRAAPGARPLVPGPGHQNIEAAAET
66
137










Molecular Recognition Features






MoRF SequenceStartStop




NANANA