Description | Mediator of RNA polymerase II transcription subunit 31 |
Sequence | MSKRFLQELEFVQCLSNPNYLQHLYQKGYFNKKEFKDFLVYLQYWKRPEYAQHLIFPQTLNILNLLIHSEEFVESLKYKQVADFLSSQQYFQWKSRR |
Length | 97 |
Position | Middle |
Organism | Nematocida displodere |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Fungi incertae sedis> Microsporidia> Nematocida. |
Aromaticity | 0.20 |
Grand average of hydropathy | -0.590 |
Instability index | 67.38 |
Isoelectric point | 9.21 |
Molecular weight | 12079.74 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364129 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription, DNA-templated GO:0006355 IEA:InterPro |
Binary Interactions |
Repeats | >MDP07588 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 127.76| 38| 45| 3| 46| 1 --------------------------------------------------------------------------- 7- 46 (68.40/48.71) QELEFVQCLSNPNYLQHlyQKGYFNKKEFK...DFLVYLQY..WK 52- 94 (59.36/28.69) QHLIFPQTLNILNLLIH..SEEFVESLKYKqvaDFLSSQQYfqWK --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) EFKDFLVYLQYW 2) LSSQQYFQWKSRR 3) YLQHLYQKGYF | 34 85 20 | 45 97 30 |
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