<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07559
Description |
Mediator of RNA polymerase II transcription subunit 17 |
Sequence | MSGADPLSSVALRPWPAPAKEALSTEDMFAQVGQLTAERKQWMRDIKEQALLDDIAAGRDAILESVEGGKQRDQDEVLSHAAMLEKLGKARVEVHSKLEWASFAAGNALNLVSLILSRDLAKHPGRKESENIYTPMFQAQNVPRSSVGLVKEALVEQDPSQMRPEERARIEYTQRRKVLAMKGSRMGALDWATDTLLKAATDLESSIRKETKYWDEILSISDKGWQMQRTRRGVRNAPFAVKYGPAEASNHFRARGLAPLRMDKDGDIILDPALTLKPKTLRVRISENDKIVGVSQATIRGALNELAIEKSIQLARASLFEEEMFYEMSLESRNLLSYGVELRDTVIHVTVPGEHSTHRKLLIDCIAQDDNSLSIHGGSQDWLAHDIAEGLRILLAHEHRMRLFRRTRLPPPMTQHKHQQPPPPLLRTLLAMFSHLNAVDSLYAYLRAVANTLKSAGLDVTLEATRELTLEKLTATIKEAKTKDLTATDQLLASLIRPFEGRAALSLPSSTESSPESLTIGTRTYIGPPHFGTEHKISLPPSLIQLLNLEHDPQRQLKFSSTGEVKSYLDWIISLDISQTLLFNEFGGRSVIKSSEPCISIVSKSSKKSSIREDDLEIELEKASLKATATAHGQLATGAAVESFTWNGSPGRQTLKDKVKSWLG |
Length | 664 |
Position | Head |
Organism | Paraphaeosphaeria sporulosa |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes>
Pleosporomycetidae> Pleosporales> Massarineae> Didymosphaeriaceae>
Paraphaeosphaeria.
|
Aromaticity | 0.05 |
Grand average of hydropathy | -0.374 |
Instability index | 38.69 |
Isoelectric point | 7.80 |
Molecular weight | 73806.43 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
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GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP07559
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 502.09| 169| 379| 84| 279| 1
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84- 279 (254.11/189.41) LEKLGKARVEVHSKlewaSFAAGNALnLVSLI...LSRDLAKHPGRKES..........ENIYTPMFQAQ...NVPRSSVGLVKealVEQDPsqmrpeerarieytQRRKVLAMKGSRMGALDWATdTLLKAATDL..ESSIRKETKYWDEILSISDKGWQMQRTRRGVRNAPFAVKYGPAEASNHFR.ARGLAPLRMDKDGdiilDPA.LTLKPK
470- 658 (247.98/137.14) LEKLTATIKEAKTK....DLTATDQL.LASLIrpfEGRAALSLPSSTESspesltigtrTYIGPPHFGTEhkiSLPPSLIQLLN...LEHDP..............QRQLKFSSTGEVKSYLDWII.SLDISQTLLfnEFGGRSVIKSSEPCISIVSKSSKKSSIREDDLEIELEKASLKATATAHGQlATGAAVESFTWNG....SPGrQTLKDK
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 80.86| 25| 295| 3| 29| 2
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3- 29 (39.80/26.47) GAdpLSSVALRPWPAPAKEALSTEDMF
301- 325 (41.05/21.00) GA..LNELAIEKSIQLARASLFEEEMF
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