<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07486

Description RNA polymerase II holoenzyme cyclin-like subunit
SequenceMSANYWDSTQRRNWLFTKDQLSSMRQKLDDENAEIVRLFPLPQPRHLAIYFNQPTKEITELLRLAKRLSIRQQAMATAQVYLKRFYIKVPIRSTNPYLVITTAIYLACKMEEAPQHIRLIVTEARQLWQDFIGLDTSRIGECEFYLISEMSSQLIVHQPYRTLTSLRSELSLADEDVHLARSVINDSFNCDLPLVCAPHIIALVAILLALVLRPNSTAPGQAASGSAAAAGLAVAQAALSQARGRDGHPGSVHEQPATGSDLKEKQQESRITRVQHFATWLADSSVDIATMVDATQEMISLYEFYEQYNDKLTREQINRFVKARGLDK
Length328
PositionKinase
OrganismMoelleriella libera RCEF 2490
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Clavicipitaceae> Moelleriella.
Aromaticity0.08
Grand average of hydropathy-0.226
Instability index51.77
Isoelectric point7.09
Molecular weight37119.01
Publications
PubMed=27071652

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP07486
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     120.11|      37|      53|     124|     162|       2
---------------------------------------------------------------------------
  124-  162 (61.80/50.32)	ARQLWQDFIGLDTSRIgeCEFYLISEMSSQL.IVHQPYRT
  180-  217 (58.31/40.53)	ARSVINDSFNCDLPLV..CAPHIIALVAILLaLVLRPNST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.60|      16|      21|      67|      82|       3
---------------------------------------------------------------------------
   67-   82 (26.44/19.02)	RLSIRQQA...MATAQVYL
   88-  106 (21.16/13.85)	KVPIRSTNpylVITTAIYL
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP07486 with CycC domain of Kingdom Fungi

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