<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07481

Description C6 zinc finger domain containing protein
SequenceMDLDLPLDGMATSHPLPVSPARLGLDATGMSTEASSGASSGVSSSGTKPAAQHNAPPGSAAAAAAAAAASHFSFRRQRASRACEVRCDAASLGVPCTNCVAFNIECRIPVPKRKKASTQQTNASGVALTSKDSDSERGGDASDEKSPRASSVAASATSGTALPPAASSAPVSSRPAVIYHTSDGTPTTTLTELQAKKQDIDDGTYVDILMKPRFTRAPITEAGRVAYLGESSNLTLLVHDQAGSTDVVHYPLPENVRGLRARLTELDDVEIDILHQRGAFLLPPRDLCDELIAAYFKWVHPVVPVINRTRFMRQYRDPNNPPSLLLLQAVLLAGSRVCDNTKLMDANGSTTPAALTFYKRAKALYDANYEDDRVTVVQSLLLMGWYWEGPEDVTKNVFYWSRVAIIVAQGSGIHRSVENSQLSTTDKRLWKRIWWTLFTRDRSVAVALGRPTHLNLEDSDVEMLVEEDFNEDEPDQPSEWPPEPVHVQFFMQYVKLCEIMGLVLSQQYSVASKGRQRNPIDLTHSDMALADWLQNCPRIVCWNAQGRNFWSGLLFSNYYTTLCLLHRAYMPPGSNSNRFGEDSAAYPSRNIAFQAANHITSIVEYLAASDQLRFCPAFIVYSLFSALIMHVLQLRSPVPSIQQATQENLRTCMSALKEVSKVWLVGKMVYTLFESILGNKAYEERLRKAGGGRHRKAQQTFAQLEQHAVQQQAQQQQYQQQQQQQQQQQQQQQQQQQQPYVDLSKRKYDEMAIDFSVNTPQPQQSYERSRPQTPSFTPAKIELGTAATMAPPSATPLLNTRQVADTFMGSSGGTGGGGPTSRPQTRPHTPFNPSLSLPTTPPDLYLVTRNSPNLSQSVWENFQPDQLFPDGTGFSMFPPTLSPLTANQSLDPTLISAMQQQQQQQQPSQQNAFVQNMPPSAPVEGNNNVPGASDTNTMQHQTVQPHGVSGFRHGGQQQQQQQLSNGNGNSGSMWQAKFDGTLPDDQSPSDSWSTGSVQGQPVPSTLNVEDWFQFFGINGDAGGMNLDLSSLT
Length1032
PositionTail
OrganismSporothrix insectorum RCEF 264
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Sordariomycetidae> Ophiostomatales> Ophiostomataceae> Sporothrix.
Aromaticity0.08
Grand average of hydropathy-0.482
Instability index58.10
Isoelectric point5.99
Molecular weight113322.39
Publications
PubMed=27071652

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
DNA binding	GO:0003677	IEA:UniProtKB-KW
DNA-binding transcription factor activity, RNA polymerase II-specific	GO:0000981	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07481
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     352.36|      70|     227|     706|     775|       1
---------------------------------------------------------------------------
  706-  775 (120.00/51.41)	QHAVQQQAQQQQYQQQQQQQQQQQQQQQQQQQQPYVD.......LSKRKYDEMAIDFSVNTPQPQ............QS.YERSRPQ...TPS
  786-  865 (87.75/35.68)	AATMAPPSATPLLNTRQVADTFMGSSGGTGGGGPTSR.......PQTRPHTPFNPSLSLPTTPPDlylvtrnspnlsQSvWENFQPD......
  885-  941 (55.45/19.93)	......TANQSLDPTLISAMQQQQQQQQPSQQNAFVQnmppsapVEGNNNVPGASD..TNTMQHQ............................
  942- 1004 (89.16/36.37)	..TVQPHG.VSGFRHGGQQQQQQQLSNGNGNSG...S.......MWQAKFDGTLPD....DQSPS............DS.WSTGSVQgqpVPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     122.83|      38|      47|     162|     200|       2
---------------------------------------------------------------------------
  162-  200 (58.98/38.07)	LPPAASSAPVSSRPAVIYhTSDGTPTTTLTELQAKKQDI
  210-  247 (63.85/36.69)	MKPRFTRAPITEAGRVAY.LGESSNLTLLVHDQAGSTDV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07481 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LDLPLDGMATSHPLPVSPARLGLDATGMSTEASSGASSGVSSSGTKPAAQHNAPPGSAAA
2) MAIDFSVNTPQPQQSYERSRPQTPSFTPAKIELGTAATMAPPSATPLLNTRQVADTFMGSSGGTGGGGPTSRPQTRPHTPFNPSLSLPTTPPDLYLVTRNSPNLSQSVWENFQPDQLFPDGTGFSMFPPTLSPLTANQSLDPTLISAMQQQQQQQQPSQQNAFVQNMPPSAPVEGNNNVPGASDTNTMQHQTVQPHGVSGFRHGGQQQQQQQLSNGNGNSGSMWQAKFDGTLPDDQSPSDSWSTGSVQGQPVPST
3) QAQQQQYQQQQQQQQQQQQQQQQQQQQPYVDLSK
4) VPKRKKASTQQTNASGVALTSKDSDSERGGDASDEKSPRASSVAASATSGTALPPAASSAPVSSRPAVIYHTSDGTPTTTLTELQAK
3
751
712
110
62
1005
745
196










Molecular Recognition Features






MoRF SequenceStartStop




1) DWFQFFG
2) WQAKFDG
1010
974
1016
980