<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07461

Description C-type cyclin
SequenceMAANYWTSTQLRFWVFSKEALAGMRQRKQDEERSLVQMYPLPECRHLNLFFFQQLIRLGKRMQVRQQALATAQVYLKRFYCTVEIRRTNPYLVAATALYLACKTEEAPQHIRQVVQEAKALWPDMAPCLETARIGECEFALIAEMRSQLIVHAPYRTLQTLQAELALAPDELAQAWTLVNDHYLTDLPLLHPPHVVAVTALFLVLVLQPSASSVPGVAGVASNVSVGLGMGGGVGSGGGNAAGAGSGGGAGAGAGAGLGSSGSTSGLGGLSSAMGGGGLSGGLGGGGGGVGGAGGADRGPSYMAPLSALASLSSLGPGSSTPSGTPSGGGAGGLGPGTPGLGGATPTTATGPGAALAQAQARAAAAAQNNSASGNSSNNNNNPGNTNNAGQGPVNSSAASADDGVSPQDGGRGTTIQWLIKWLAESGFDMDAIIDCTQEMISLYVCADEYNEKQTREQINRFIKARGLDR
Length470
PositionKinase
OrganismSporothrix insectorum RCEF 264
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Sordariomycetidae> Ophiostomatales> Ophiostomataceae> Sporothrix.
Aromaticity0.06
Grand average of hydropathy-0.088
Instability index43.02
Isoelectric point6.32
Molecular weight47987.38
Publications
PubMed=27071652

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07461
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     101.32|      22|      22|     247|     268|       1
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  247-  268 (43.09/14.76)	GGGAGAGAGAGLGSSGSTSGLG
  285-  303 (28.23/ 7.02)	GGGGGVG.GAG.GADRGPSYM.
  331-  351 (30.00/ 7.94)	AGGLGPGT.PGLGGATPTTATG
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.85|      18|      22|     375|     392|       2
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  375-  392 (33.99/18.27)	NSSNNNNNPG.NTNNAGQG
  395-  413 (26.86/12.88)	NSSAASADDGvSPQDGGRG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.37|      16|      49|     219|     235|       3
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  219-  235 (26.06/14.99)	GVASNVSVGlGMGGGVG
  269-  284 (29.31/13.23)	GLSSAMGGG.GLSGGLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.31|      19|      24|      63|      84|       4
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   63-   84 (26.30/24.19)	QVRQQALATAQVYLKrfyCTVE
   87-  105 (31.01/18.38)	RTNPYLVAATALYLA...CKTE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.18|      26|      26|     136|     161|       5
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  136-  161 (45.20/35.37)	ECEFALIAEMRSQ..LIVHAPYRT.LQTL
  162-  190 (33.97/24.75)	QAELALAPDELAQawTLVNDHYLTdLPLL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07461 with CycC domain of Kingdom Fungi
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