<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07458

Description R3h domain protein
SequenceMNSQQPQGDFYAGYAGPLNHSPNPTRPGYATTAGIPSALSGARRNNQPGDLGNLPGSASLYADDRFASFEGGGGGGGGGGQRFDRNTATQAGLQNAFNMFNGSAQSAWHYNGAGSAATMNAPMNDGSRIRATGRRLPLHAEWTTTSDSPLGNQNVHNVSFYPQQQQQQQQQQQQQQQQQQQQQQQQHLVAQPSLGLPNAGSPDPFNVQPPTVNLQSYGSSDMRAYSDSKKDMGDLIPTAIVIKNIPFNVRKEYLTSVMIDLHLPQPYAFNYHFDQGVFRGLAFANFQNAQDTALVIERMNGLDIQGRKLRVEYKKMLPEHERERIEREKREKRGQLEEQHRGPAHQISISSMTTATSIQRPPTTERATGRIDLNDPHTLRFYLELYMFHNDDSREVYIFPTDTSPEDRRMIHILAHNMGLEHTSIGEGENRQIHVSKMKFATGGRQSSVQQPGVTLDGHPRGLSRAATYDFNDRQHPSIHSVGRGPTLAVPSSPENHQHGMNGLRGVKSFADLRSFSPSPSPSLVSSAVLGAPPTNGHNTGGVPFLTHYPSDGPFGPSLATPTTPGSVMNPPSATADPSSLVNGLGSLGLGSSSFDGNGGLSGRPRDTPGAIGSQRPGANSNGTRANPERQPRGPGGDWENPGGFSRGRSNGHMQRSSDSSDNAGRVGASHGPSSLF
Length677
PositionTail
OrganismSporothrix insectorum RCEF 264
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Sordariomycetidae> Ophiostomatales> Ophiostomataceae> Sporothrix.
Aromaticity0.07
Grand average of hydropathy-0.808
Instability index58.05
Isoelectric point8.87
Molecular weight73071.38
Publications
PubMed=27071652

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
RNA binding	GO:0003723	IEA:UniProtKB-UniRule

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07458
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     211.29|      52|      56|     520|     571|       1
---------------------------------------------------------------------------
  486-  521 (60.38/20.97)	PTL....AVPSSPENHQHGMNGLRGVKSFADLRS..FSPS...................PS
  522-  579 (92.87/35.96)	PSLVSS.AVLGAPPTNGHNTGGVPFLTHYPSDGP..FGPSLATPTTPGSVMNPpsatadPS
  580-  628 (58.04/19.89)	.SLVNGlGSLGLGSSSFDGNGG...LSGRPRDTPgaIGSQRPGANSNGTRANP........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.49|       9|      15|     163|     173|       2
---------------------------------------------------------------------------
  163-  171 (18.96/12.89)	QQQQQQQQQ
  179-  187 (19.53/ 6.20)	QQQQQQQQH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.21|      15|      19|      11|      28|       3
---------------------------------------------------------------------------
    3-   17 (29.31/ 9.61)	SQQPQGDFYAGYAG.P
   21-   36 (25.89/15.11)	SPNPTRPGYATTAGiP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      92.61|      22|      24|      81|     103|       4
---------------------------------------------------------------------------
   64-   79 (21.42/10.11)	....DRFASFEGGGGGG....GGG
   81-  103 (35.07/29.65)	QR.FDRNTATQAGLQNAfNMFNGS
  105-  127 (36.11/24.18)	QSaWHYNGAGSAATMNA.PMNDGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.31|      18|      24|     631|     650|       5
---------------------------------------------------------------------------
  631-  650 (32.30/18.65)	QPRGPGGDweNPG..GFSRGRS
  655-  674 (29.00/10.52)	QRSSDSSD..NAGrvGASHGPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      84.32|      22|      24|     407|     428|       6
---------------------------------------------------------------------------
  401-  420 (27.92/15.04)	..TDTSP.EDRRMIHI..LAHNMGL
  421-  444 (32.82/19.05)	EHTSIGE.GENRQIHVskMKFATGG
  445-  463 (23.58/11.50)	RQSSVQQpG....VTL..DGHPRGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.42|      15|      15|     189|     203|       7
---------------------------------------------------------------------------
  189-  203 (27.63/13.77)	VAQPSLGLPNAGSPD
  207-  221 (27.79/13.89)	VQPPTVNLQSYGSSD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.24|      16|      35|     325|     340|       8
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  325-  340 (26.31/16.19)	IEREKREKRG....QLEEQH
  358-  377 (21.93/12.24)	IQRPPTTERAtgriDLNDPH
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07458 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ADDRFASFEGGGGGGGGGGQRFDRNTATQAGLQNAFN
2) AQSAWHYNGAGSAATMNAPMNDGSRIRATGRRLPLHAEWTTTSDSPLGNQNVHNVSFYPQQQQQQQQQQQQQQQQQQQQQQQQHLVAQPSLGLPNAGSPDPFNVQPPTVNL
3) DRRMIHILAHNMGLEHTSIGEGENRQIHVSKMKFATGGRQSSVQQPGVTLDGHPRGLSRAATYDFNDRQHPSIHSVGRGPTLAVPSSPENHQHGMNGLRGVKSFADLRSFSPSPSPSLVSSAVLGAPPTNGHNTGGVPFLTHYPSDGPFGPSLATPTTPGSVMNPPSATADPSSLVNGLGSLGLGSSSFDGNGGLSGRPRDTPGAIGSQRPGANSNGTRANPERQPRGPGGDWENPGGFSRGRSNGHMQRSSDSSDNAGRVGASHGPSSLF
4) KMLPEHERERIEREKREKRGQLEEQHRGPAHQISISSMTTATSIQRPPTTERATGRID
5) MNSQQPQGDFYAGYAGPLNHSPNPTRPGYATTAGIPSALSGARRNNQPGDLGNLPGS
62
104
407
315
1
98
214
677
372
57










Molecular Recognition Features






MoRF SequenceStartStop




NANANA