<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07453

Description Uncharacterized protein
SequenceMATMTKRPRLTGSQDLLSYYNLTPLYDKYVRPYSPPNRAAGLDQTLFRYISDLPGKYDVEPDGYLINLLRDPQAVESGPKIKRLDPETLEDAFSLKEGPVPGFDASILGTDDGGSSTYSGVNPGQYLHTERGEYGASAGDEMNKRERKKKKKKRKHSHDHDEDGHTHEHKKKKKRKKASVG
Length181
PositionHead
OrganismPhycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC 33097 / NRRL 1555)
KingdomFungi
LineageEukaryota> Fungi> Fungi incertae sedis> Mucoromycota> Mucoromycotina> Mucoromycetes> Mucorales> Phycomycetaceae> Phycomyces.
Aromaticity0.08
Grand average of hydropathy-1.156
Instability index39.11
Isoelectric point9.27
Molecular weight20391.59
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP07453
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.67|      18|      19|     140|     157|       1
---------------------------------------------------------------------------
  140-  157 (32.64/19.54)	DEMNK.RERKKKKKKRKHS
  161-  179 (29.03/16.69)	DEDGHtHEHKKKKKRKKAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.56|      14|      18|      68|      85|       2
---------------------------------------------------------------------------
   54-   67 (23.44/ 6.67)	PGKYDVEPDGYLIN
   72-   85 (22.12/14.25)	PQAVESGPKIKRLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.05|      16|      19|      98|     116|       3
---------------------------------------------------------------------------
   98-  116 (26.05/20.98)	GPVPGfdaSILGTDDG..GSS
  120-  137 (27.00/13.68)	GVNPG...QYLHTERGeyGAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.55|      11|      27|       9|      19|       4
---------------------------------------------------------------------------
    9-   19 (19.55/13.44)	RLTG.SQDLLSY
   38-   49 (16.00/ 9.86)	RAAGlDQTLFRY
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP07453 with Med19 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) FDASILGTDDGGSSTYSGVNPGQYLHTERGEYGASAGDEMNKRERKKKKKKRKHSHDHDEDGHTHEHKKKKKRKKASVG
103
181

Molecular Recognition Features

MoRF SequenceStartStop
1) EMNKRERKKKKKKRKHSHDHDEDGHTHEHKKKKKRKKASV
2) LDQTLFRYI
3) QDLLSYYNLTPLYDKYVRPY
4) YLINLLRD
141
42
14
64
180
50
33
71