<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07442

Description Serine/threonine-protein kinase domain protein
SequenceMPLGSRPTAGHESRQQQPQPQYPQLQQHSGAQWNPSAAAPHMPFAPSSLSRGSSFLAPTSTHRNQNYAHRRIPEGVGRSGGYQPKARVTERYRIVGFISSGTYGRVYKAVNRNNIVTSTNGAPVPTGHEVAIKKFKPDKEGEQLSYTGISQSAIREMSLCSELNHANVIRLIEIILEDKCIFMVFDYAEHDLLQIIHHHTQQPRHPIPPATVKSIMFQLLNGCHYLHTNWVLHRDLKPANIMVSSSGGVKIGDLGLARRFDKPLHSLFSGDKVVVTIWYRAPELILGSYHYTPAIDMWAIGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRNQMMKIMEIMGAPTKDKWPLLATMPEYGQLNALQASMAAHHGRHSHGAPLASNLEKWYHNTISNAPSSTNTSLGASTSLSSLGQEGYRLLSGLLEYDPVRRLTAAQALQLPFFSTGDKVTANAFEGLKVDYPHRRVSQDDNDIRTSSLPGTKRSGLADDSLLRPSKRVRE
Length501
PositionKinase
OrganismBeauveria brongniartii RCEF 3172
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Cordycipitaceae> Beauveria> Beauveria brongniartii.
Aromaticity0.08
Grand average of hydropathy-0.439
Instability index49.12
Isoelectric point9.55
Molecular weight55706.80
Publications
PubMed=27071652

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP07442
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.91|      20|      20|      75|      94|       1
---------------------------------------------------------------------------
   75-   94 (35.78/19.52)	GVGRSGGYQPKARVTERYRI
   96-  115 (35.13/19.06)	GFISSGTYGRVYKAVNRNNI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.71|      39|     319|     117|     159|       2
---------------------------------------------------------------------------
  117-  159 (62.83/46.55)	TSTNGAPVP...TGHEVAIKKFkpdkEGEQLSYTG..ISQ..SAIREMSL
  434-  479 (52.88/30.30)	TAAQALQLPffsTGDKVTANAF....EGLKVDYPHrrVSQddNDIRTSSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.21|      15|      15|      11|      25|       3
---------------------------------------------------------------------------
   11-   25 (28.98/15.83)	HESRQQQPQPQYPQL
   28-   42 (29.23/16.03)	HSGAQWNPSAAAPHM
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP07442 with CDK8 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MPLGSRPTAGHESRQQQPQPQYPQLQQHSGAQWNPSAAAPHMPFAPSSLSRGSSFLAPTSTHRNQNYAHRRIPEGVGRSGGYQ
1
83

Molecular Recognition Features

MoRF SequenceStartStop
NANANA