<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07406

Description Mediator of RNA polymerase II transcription subunit 16 (Fragment)
SequenceLLAVRTVALNQPSSLAHRPWWTLVDAIAHRHEVPESTPMTEAKMPLMLENGMNGSMQVDQLDVDDLFGDGVGLSLHTARPLTKHLRQRVDELRTRGCCQGVAWSRSGAIASISPDGKTLEARFLRSHPDDGNWGLSEPTKVDLITINASSPIVHLAWASTASPELAVVDATGRVAILTYSITLNRPFATRKWDHDPSDDLHAIVGSYWLPLAPQAKQYYVSHGPAVKDGNQYRYESSFVHAYGPWHPNPSKSAFLCVTTNGHLKMFWAQNNNKIEETTLELESVNSSDDLITHAALHSDKSNLWIALATTSKQLRLVRVGINWGLPQSQSDNKPPPGSQALNPTMQEKHVAISSWLPSGSSTTPIDSAANQLTHLEILPSTLDHTGQGWAPLVILAVRTYLPTPNTPYQETQSIIDKWEVLNDQAQSLHPAFEQLGSRRNSTGAAPAPTSRLKKHDPIVVNKVIIGVHTLQYGRVICLAFSDGSVEYRDRFTLQEIYNEMNLDRVMTLNQVGFTFQDESPCLQMAFSPTNCSIVKIQDDGKVKWSKLHYPLGDIGNSSQDEPYAATLAALTVAASTATFNNINYDDILAVARPYADKKRFTFDWINEIVRMLKVPVDYSEDTHHDSLVRNSSLQMCLSILNHLGYKGMFQPRSFGGKFAMLALNARNVVILITIASNTPVNIREKLSPLDEHEVVDALAGCAKWSLDLLSWLTDSLFALLDDPQFLALLTPQRFSEISTYLQSRSDVSLHLLLCSSTRGFLSAVCRRILHLEILSNRAIEFYERRAAMQNATDPSSQGKSLHVVLYKAYQKMQRVTSSSLIKVQEFDRLLTVLNNDIRAAYQNSLASLASKNPPGAGGQKAMDAQIKNAQIHCELNMLLASSPPPAFLSVLLKFFNSDLKTYRAQADPSKLFFADFDLLEIDDDRRALAARKAKGRFIDVFKRVELAAPPARGTKEGDEAKLAQWRRCVRCSAVMEDVFGSRPGFTFVLAQQRKCSCGGHWGLLPKGALML
Length1011
PositionTail
OrganismColletotrichum incanum
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Glomerellales> Glomerellaceae> Colletotrichum> Colletotrichum spaethianum species complex.
Aromaticity0.08
Grand average of hydropathy-0.223
Instability index41.01
Isoelectric point7.45
Molecular weight112178.49
Publications









Function






Annotated function

Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors. 


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07406
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.33|      29|     158|     716|     748|       1
---------------------------------------------------------------------------
  697-  726 (48.24/28.21)	ALAGCAKWSlDLLSWL...TD.SLFALL..DDPQFL
  727-  761 (34.09/29.88)	ALLTPQRFS.EISTYLqsrSDvSLHLLLcsSTRGFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      94.94|      23|      93|     195|     217|       2
---------------------------------------------------------------------------
  195-  217 (44.36/30.68)	DPSDDL..HAIVGS....YWLPLAPQAKQ
  285-  313 (30.11/18.18)	NSSDDLitHAALHSdksnLWIALATTSKQ
  343-  357 (20.46/ 9.72)	PTMQEK..HVAISS.....WLP.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.14|      14|      96|     871|     891|       6
---------------------------------------------------------------------------
  871-  884 (25.16/23.28)	IHCELNMLLASSPP
  895-  908 (23.98/ 6.50)	FNSDLKTYRAQADP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.30|      18|      26|     953|     971|       8
---------------------------------------------------------------------------
  953-  971 (31.63/27.97)	GTKEGDEAKLAQWRRCvRC
  980-  997 (35.67/26.19)	GSRPGFTFVLAQQRKC.SC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     291.09|      90|     422|      53|     149|      11
---------------------------------------------------------------------------
   53-  149 (147.18/115.19)	NGSMQV.DQLDVDDLFGDgvglsLHTARPLTkhLRQRVDELRTRGCCQGVAWSRSG.AIASISPDGKTLEARFLRSHPDDGNWGLSEPTKVDL..ITINAS
  482-  575 (143.91/95.58)	DGSVEYrDRFTLQEIYNE.....MNLDRVMT..LNQVGFTFQDESPCLQMAFSPTNcSIVKIQDDGKVKWSKLHYPLGDIGNSSQDEPYAATLaaLTVAAS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07406 with Med16 domain of Kingdom Fungi
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