<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07394

Description Transcription factor subunit med10
SequenceMVPRASVSFTCTFCYQPSDDPPHVVGHEARLTCSPCHAALIDLAICWVCGEIVYRGDDKLVYRGVPLVELFDEGHDVDEEERSMTRRVAGTAGKGRMKEVDMPPLCAACFLGTEGEDVLQKGLKRVERADGGLSRARWDAGEARAGQLRRAPASIRSSSRGSSSLRRAGDGSNDGAKGHLVEPPAESTIYVSINDPLGQPAFKPSPTKPIPVWMQPFRRIAESEEQWQKASTPHPLSGFAQSPATSTPGTSILGSARSLTPINQPITAVRRPSPLQTPPGASSVRTPPEIRRAPPLSWVSNEPLKRPSSRIASRLEKSDMTTSSGYVTPPETPSEQMMRYKTPPPQLRHTRPQSPLAPARVPRRNAVRRTPLPQSSEYLERYNPIRSPSPRLRDKQPVMVSLRRASRGAGLGLSRGTTSIANESSSSQGQNQSTVGRLHSDGADSPRELGKKKNMQDLRKLFDGIACPTPTFLVPPAHPANASQLQPSIDQTALFSASSLTSQLNLGNNPGRLAHDTELIRAALLQATKYAPNHEENTNATATMAPLDKPTPAELEQQLKDTIQDLYQIMVQVTTYNATPSNPSGPALSESVQALSQSLQRVHMTATAGAPPSPDLPGALPKIPPELVQYVENGRNPDIYTREFVELVRRGNQLMKGKMGAFAQFRDVLADHMERGMPELREDVARVLEGTKVVGSGRPGAN
Length702
PositionMiddle
OrganismColletotrichum incanum
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Glomerellales> Glomerellaceae> Colletotrichum> Colletotrichum spaethianum species complex.
Aromaticity0.04
Grand average of hydropathy-0.580
Instability index62.38
Isoelectric point9.34
Molecular weight76226.33
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07394
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     160.12|      34|      37|     233|     266|       1
---------------------------------------------------------------------------
  182-  207 (31.64/ 9.64)	....EPPAESTIYVSI..........NDPLGQPA...fkPSPT
  208-  236 (37.42/12.62)	KPI...PVWMQPFRRIAESeeqwQKAST...........PHPL
  237-  275 (55.65/22.04)	SGFAQSPATSTPGTSILGS....ARSLTPINQPItavrrPSPL
  324-  346 (35.40/11.58)	SGYVTPP..ETPSEQMM.......RYKTPPPQ...........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     125.38|      40|      54|     389|     430|       2
---------------------------------------------------------------------------
  389-  430 (61.10/39.71)	SPRLRDKQPVMVSLRRASRgaGLGLSRGTTSI..ANESSSSQGQ
  445-  486 (64.28/35.91)	SPRELGKKKNMQDLRKLFD..GIACPTPTFLVppAHPANASQLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     148.24|      50|      70|     509|     567|       3
---------------------------------------------------------------------------
  509-  567 (68.32/63.28)	NPGRLAHdTELIRaALLQ........ATKYAPNHEENTNAtatmapLDKpTPAELEQQLKD.TIQDLY
  582-  640 (79.91/45.95)	NPSGPAL.SESVQ.ALSQslqrvhmtATAGAPPSPDLPGA......LPK.IPPELVQYVENgRNPDIY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.72|      21|      31|     128|     148|       4
---------------------------------------------------------------------------
  128-  148 (36.60/22.11)	RADGGLSRARWDAGEARAGQL
  160-  180 (36.13/21.72)	RGSSSLRRAGDGSNDGAKGHL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.06|      29|      74|     276|     307|       5
---------------------------------------------------------------------------
  276-  352 (27.75/15.45)	QTPPGASSVRTPPEIRRAP.PLSwvsNEPLKrpssriasrleksdmttssgyvtppetpseqmmryktpppqlrhtR..P
  353-  384 (45.31/18.55)	QSPLAPARVPRRNAVRRTPlPQS...SEYLE.............................................RynP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.10|      20|      38|     642|     661|       7
---------------------------------------------------------------------------
  642-  661 (35.49/23.40)	REFVELVRRGNQLM.KGKMGA
  681-  701 (29.61/18.33)	REDVARVLEGTKVVgSGRPGA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07394 with Med10 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AESEEQWQKASTPHPLSGFAQSPATSTPGTSILGSARSLTPINQPITAVRRPSPLQTPPGASSVRTPPEIRRAPPLSWVSNEPLKRPSSRIASRLEKSDMTTSSGYVTPPETPSEQMMRYKTPPPQLRHTRPQSPLAPARVPRRNAVRRTPLPQSSEYLERYNPIRSPSPRLRDKQPVMVSLRRASRGAGLGLSRGTTSIANESSSSQGQNQSTVGRLHSDGADSPRELGKKKNMQDLRKL
2) HMERGMPELREDVARVLEGTKVVGSGRPGAN
3) LLQATKYAPNHEENTNATATMAPLDKPTPAELEQQL
4) SLQRVHMTATAGAPPSPDLPGALPKIPPELV
5) SRARWDAGEARAGQLRRAPASIRSSSRGSSSLRRAGDGSNDGAKGHLVEPPAESTIYVSINDPLGQPAFKPSPTKPIPVWMQPFRR
221
672
524
598
134
461
702
559
628
219










Molecular Recognition Features






MoRF SequenceStartStop




1) SEYLERYNPIR
376
386