<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07367

Description Uncharacterized protein
SequenceMSSSKVAAEPVAPYVSRPPDWLKRAHASADVGYSGFFPPVPSAREEQLNEQTAQHGYISQPEVNAENFNAKAEVTKAFKTGNTLDDLKQLLDAVIERRAENAAKLPPTSFKIPGRVTFNEARRVNWVSELANPDVPLHKIGKSVPHGFKGHDLLEMLETHKVAVPRAVWYVRVLGANETQGMRNRPNFHPAMYSVEWANVVTSYFKKLLDKIALPSAPRAALNIKQTFNSILANTNAREEWLAKFTYILDLTREFYVESLVDHPTFLSWLAQLMSGSNLAQAGFATCLLEDYFDGLLSHRVFARPLIEGCLSKLNEIDASPVKENLGFLASAIKTILQRAFPVVPDAFVSPGMWTTYSPVLRDMFRDASDFTEVEQRNDALAFRTLPVREMDRVRSMMSEIQALNAVTMDTDLTALARRNSSLALLLTWAASPAQHGVHRPFLVATLIARRAEYEDDPDALQNALIEWMDGSDECMASQSARGAARLMGELARVGLFSYERFLQRILARGDTERHQATLRAMPVWKENGVILRQRKIALYGVRAGSRETEEDHIQRAIRAEIRQELPYFFGGSYPATEPSGTLRSRMPTLFGAHKFEQVRTVAHWLLPIAMDRLKKCSVMDTAVVSKNYSVLSEVLAATHCFSSLCELNIAVLQKATAPELLMAVISNLRRFAFIFKCMDVIPTLDGALAVSHHSIRSRPAQLRSLLALLQVLNRGDETQSATLHLVAADVDASVQALRPPLSSPEEMPSLDLELAQLALDPAPNAPSILAHGLWSKFKTKANWGLSAAESTFASLRQFTPETMPPQPPPDTAGKFATFLWEVDQLLAGDLDAHLLECFRGPVFTSSDEMRVCDATIWNIVVSIAVELVVRGCASTQTILRGLVYPAWTLGSYQSVNEEEGGIYESFLLASVQLGHSLLICTVNQDEDMPPRGLAECQQLKARRAMLYDDGEFSELVTALRSLVAWESSPNERLKEAASSLRTALQVNREFWFIARKNLDLVRDVFLTEQPPSESLVEMLRSILGDPANALDHEEEVATTDWQNISSRVNPWTFARTSINLHLTLQELVKGLVTEETRPQAERDLDTFTAGLFDSAVTAEETDLLGDVLRGISGPVVAKFVNNGIRRLTLLLEESAADDFPPDIVEPYLRRAGEVLRLLAGVLAPLRDDPGKIPAIEAEVQDDFVRALHKKLSVVESKLSHVGDALDLAIQVVVFLARMLQFSLGLGRAWSDRLKDCGVELMDCIVRMCIAFGGGVLTDQRTFTILLDTASIMVDDYPKDPKTAAADLFRNIPTLDPARLPGFLPHDFNQRLVFILPYRPSNHYTSDLVYAHPETNGSLTYGAPVQHRPWEWIESIEARNSPTLDEHGEHVVANSTSIPLELFGARPTAERVYTGDEPARLGDLLLQQDTFASGSVFENDWRQSRLARNDAQNLDAPSPAESGEHEQQESGPAVDPFQHEPSPAPTVLSRTSAFAGSASASSRRGSPAIQMGRGGTAEQQGTMSSRGSKRKASTASSSVIEIDDGPDEAEQSRPTAAKRRRARPAPATATRARGKKK
Length1557
PositionKinase
OrganismExidia glandulosa HHB12029
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Auriculariales> Exidiaceae> Exidia.
Aromaticity0.07
Grand average of hydropathy-0.208
Instability index51.68
Isoelectric point5.64
Molecular weight172173.62
Publications
PubMed=26659563

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07367
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      92.55|      23|      26|    1462|    1486|       1
---------------------------------------------------------------------------
 1463- 1485 (39.07/19.64)	PAPTVLSR..TSAFAGSASA..SSRRG
 1487- 1512 (25.32/ 7.55)	PA.IQMGRggTAEQQGTMSSrgSKRKA
 1534- 1554 (28.16/ 9.13)	..PTAAKR..RRARPAPATA..TRARG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     121.88|      25|      26|     359|     383|       2
---------------------------------------------------------------------------
  321-  341 (31.23/15.96)	PVKENLGFLAS...............AIKTILQR....AF
  342-  356 (18.05/ 6.03)	PVVPDAFVSPG...............MWTT..........
  359-  383 (44.62/26.05)	PVLRDMFRDAS...............DFTEVEQRNDALAF
  387-  425 (27.98/13.51)	PV.REMDRVRSmmseiqalnavtmdtDLTALARRNSSLAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     191.13|      59|      59|     943|    1001|       3
---------------------------------------------------------------------------
  938-  996 (95.75/48.58)	QQLKARRAMLYDDGEFSE.LVTALRSLVAWESSPNERLKEAASSLRTALQVNREFWFIAR
  997- 1056 (95.38/48.37)	KNLDLVRDVFLTEQPPSEsLVEMLRSILGDPANALDHEEEVATTDWQNISSRVNPWTFAR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     147.33|      47|      60|     700|     749|       4
---------------------------------------------------------------------------
  700-  749 (71.15/42.76)	PA.QLRSLLAllQVLNRGDETQsATLHLVAADVD.ASVQALRPPLSSPEEMP
  762-  810 (76.19/37.77)	PApNAPSILA..HGLWSKFKTK.ANWGLSAAESTfASLRQFTPETMPPQPPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.03|      12|      62|    1325|    1339|       5
---------------------------------------------------------------------------
 1312- 1323 (22.12/13.12)	LVFILPYRPSNH
 1328- 1339 (20.90/ 6.43)	LVYAHPETNGSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.03|      15|      24|     551|     571|       6
---------------------------------------------------------------------------
  551-  571 (21.26/26.17)	EDhiqraiRAEIRQELPYFFG
  578-  592 (27.77/16.55)	EP......SGTLRSRMPTLFG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      29.84|      10|      26|    1068|    1077|       8
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 1068- 1077 (16.85/10.57)	LVKGLVT.EET
 1092- 1102 (12.99/ 6.37)	LFDSAVTaEET
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.33|      16|      26|    1204|    1227|       9
---------------------------------------------------------------------------
 1204- 1219 (25.68/28.76)	DAL.DLAIQVVVFLARM
 1232- 1248 (25.65/ 8.96)	DRLkDCGVELMDCIVRM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      85.65|      26|      27|    1115|    1141|      16
---------------------------------------------------------------------------
 1115- 1137 (29.80/17.11)	............P.VVAKFVNNGIRRLTLLLEESAA
 1138- 1165 (32.96/26.13)	DDfP........PdIVEPYLRRAGEVLRLLAGVLAP
 1168- 1197 (22.89/11.40)	DD.PgkipaieaE.VQDDFVRALHKKLSVV..ES..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.62|      13|      17|     882|     894|      17
---------------------------------------------------------------------------
  882-  894 (25.86/21.28)	GLVYPAWTLGSYQ
  901-  913 (22.76/17.58)	GGIYESFLLASVQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.90|      19|      25|    1418|    1438|      19
---------------------------------------------------------------------------
 1418- 1438 (29.36/26.00)	ENDWRQSRLARNDAQNldAPS
 1444- 1462 (35.55/24.02)	EHEQQESGPAVDPFQH..EPS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07367 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FENDWRQSRLARNDAQNLDAPSPAESGEHEQQESGPAVDPFQHEPSPAPTVLSRTSAFAGSASASSRRGSPAIQMGRGGTAEQQGTMSSRGSKRKASTASSSVIEIDDGPDEAEQSRPTAAKRRRARPAPATATRARGKKK
1417
1557










Molecular Recognition Features






MoRF SequenceStartStop




1) SSVIEIDDGPDEAEQSRPTAAKRRRARPAPATATRARGKKK
2) WLKRAHA
1517
21
1557
27