Description | Mediator of RNA polymerase II transcription subunit 31 |
Sequence | MMDSSEETKEMDASPSPKNIYKDPDDGRQRFLLELEFVQCLANPTYIHYLAQNRYFEDEAFIGYLKYLQYWQRPEYIKFIMYPHSLFFLEQLQNESFRNAMAHPANKELAHRQQFYFWKNYRNNRLKHILPRPLPESVATPQAAAPPPAPATSRASTIASSTPIPTSAAGSIPSPMPYAIPSGSSLAKNDPRNSGVDRRKKK |
Length | 202 |
Position | Middle |
Organism | Daucus carota subsp. sativus (Carrot) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Apiales> Apiaceae> Apioideae> Scandiceae> Daucinae> Daucus> Daucus sect. Daucus. |
Aromaticity | 0.12 |
Grand average of hydropathy | -0.724 |
Instability index | 63.14 |
Isoelectric point | 9.21 |
Molecular weight | 23216.04 |
Publications | PubMed=27158781 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364129 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription, DNA-templated GO:0006355 IEA:InterPro |
Binary Interactions |
Repeats | >MDP07359 No repeats found No repeats found |
MoRF Sequence | Start | Stop |
1) PKNIY 2) PRNSGVDRRKKK 3) YFWKNYR | 17 191 116 | 21 202 122 |
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