<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07338

Description Uncharacterized protein
SequenceMAKGEKETLPIYELHPPPWLPKTHTSADIGYTGFHPPRPGDVEEVLTDVTVQNGLILPPLVSAEGWTAINQMQDPQRLQHLEDLMNKIFLRRAENIPPVPASTFRMPSRVTLNDTKRQQWFADLANPDVPLYKLGKNVPHGAKGHDLLDLLHSNNVAIERAVWFLRVFGGNESAGLRNKPGYNPTQYSIEWANVVTSYMKKQLADIALPTAPRPGLNIKMTFKNMLADPQSRERWMSRFSYCLELLRTFYAEGLVDSRTFLTWLVQQTWTCNLAQLGFVARLADEYLDGVLINRALTHHFVDACLNRLDEARHIRSTAAKEFLSSLESTLRNLVARSFLALPDAFISPRVWQLHSELLGDILSTAAALAEGTLAPSAQVLQQTFQELFADVRRRNEAMLFRHLPPRVVGSLTSALSDIKLLNSLSGDTDISSVVFFEDALALVPHPSFARKLDILLTWSVTSLQYGDHRPYAAACILQEWRRKAGERAIRHEAEAPDQFIQDQVFDWLDGSSDAADPVNLPAVSLLFGQLVKQGLFCYQQYVQRLIARGEAGLSFSQEGYSRHRDFLRWTCLHTADASVIRQRKVTLYGVRVRQTPEDEHEHEMRSELRALLPEVFNGQARCAQSLATKFWERCPTLLTSPRYEQVRTVREWLLPILRKHIARYQALANGSSDVLKTFTLSVILMAHTKCYGSLLELTLFTLERATTHQLLVVVIETLCQHMEVWACMNVMRNVAAGLYAAHQYWRGRGIHSRQLLSLLMQVDKGRYLEQAQRDQVTNDVSAFSHALHPMSQSSNTVPVHLPEVLLLATDPNPEAPSNLAKSLWYKYMTTANWAWTVWDNTIASLRQIPVMIADSQGRRACALKYAHFLWQVDQHLPQGFDSHVLEWFLGSGKNEAAALTVEVWDVVRVVLLQLCIYGALTTTTILQGLIYSVWQSAATASTPEQGQSLEVLLSAVNALFEHLLLKDECGTGLPPADIFEAQGLQTRRRDVFREPHFSKLVDNLPALVLVEHNSFLSDALRQGSCALRESICRFSVFRLGVYRDLDAVRYAFEKLLECRTVSEELHAHLVAALRLMLRDPSQEDSDGFATMSSLLTPWKLAATAIEMRLTLKQLAEGLTRESMQKAANVSLDRLGHFVFHQCKSAEEVDFVAEMMTEVSIDVAGKFVNAGLQRIVELFQEPFEPTKADDVHAFVANTGEVLRLLSKIVERFRQNATLPTLDPAAQDKFFSGLVGRFAQMEEAWATGRSDGAEDSLNQASHCIIFLARLLQFDLGFPGAWTPQATELSSTLCGTLFDLVLLHADGSGLDIVAFPLLFDTLLYLLDETSVDPKSATLDPFRNYPEIELSQLPAGTPPEYRARIRTLLPYVALNPVVADLAYATRDASGALTLTQPVQHRPWEWTEYLGDVSPGEVNPRTDERAGTRIEEHGSVRNSASVALELFGARLTGDILVAAHTGGDQRVEAALRTFQDDLSSESVFARDWREARVALNDEGSRSRSVTDHEDGVAPTGQYQGASRRGSPALSTRSGVARVSGSSSAGSRRQSPATSTTVGHPLSRLSVSTASEPIDVDAFDFANVATTSTAKRRLDDDEVQIVEGPARTSKKPRGKVGSRTKGKKR
Length1619
PositionKinase
OrganismDaedalea quercina L-15889
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Polyporales> Daedalea.
Aromaticity0.08
Grand average of hydropathy-0.182
Instability index43.48
Isoelectric point6.15
Molecular weight180709.42
Publications
PubMed=26659563

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07338
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.42|      15|      19|    1294|    1308|       1
---------------------------------------------------------------------------
 1294- 1308 (26.01/16.61)	LFDLVLLHADGSGLD
 1315- 1329 (25.41/16.04)	LFDTLLYLLDETSVD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      98.38|      24|      59|     338|     361|       2
---------------------------------------------------------------------------
  338-  361 (42.54/25.68)	FLALPDAFISPRVWQLHSELLGDI
  365-  386 (25.49/12.11)	AAALAEGTLAPSA.QVLQQTFQE.
  400-  418 (30.34/15.97)	FRHLP.....PRVVGSLTSALSDI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.46|      20|      24|    1506|    1529|       3
---------------------------------------------------------------------------
 1510- 1529 (37.55/28.04)	TGQYQGASRRGSPALSTRSG
 1534- 1553 (35.91/16.16)	SGSSSAGSRRQSPATSTTVG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.81|      24|      24|    1203|    1226|       4
---------------------------------------------------------------------------
 1203- 1226 (40.49/27.34)	LLSKIVERFRQ..NATLPTLDPAAQD
 1228- 1253 (38.32/25.42)	FFSGLVGRFAQmeEAWATGRSDGAED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      84.67|      18|      19|     919|     937|       6
---------------------------------------------------------------------------
   46-   63 (30.19/12.85)	LTDVTVQNGLILPPLVSA
  920-  937 (31.47/18.41)	LTTTTILQGLIYSVWQSA
  939-  955 (23.01/10.40)	.TASTPEQGQSLEVLLSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.94|      11|      19|     670|     680|       8
---------------------------------------------------------------------------
  670-  680 (19.29/12.53)	GSSDVLKTFTL
  692-  702 (18.66/11.86)	GSLLELTLFTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     101.25|      25|      25|     221|     245|       9
---------------------------------------------------------------------------
  200-  220 (19.04/ 6.24)	...KKQLADialPTA.....PRPGLNIKM
  221-  245 (45.13/25.01)	TF.KNMLAD...PQSRERWMSRFSYCLEL
  248-  273 (37.07/19.20)	TFyAEGLVD...SRTFLTWLVQQTWTCNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.07|      28|     766|     275|     308|      10
---------------------------------------------------------------------------
  275-  308 (39.58/48.59)	QLGFVARLADEyldgVLINRAltHHFVDACLNRL
 1147- 1174 (48.49/36.43)	EVDFVAEMMTE....VSIDVA..GKFVNAGLQRI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     176.80|      57|      61|     475|     533|      11
---------------------------------------------------------------------------
  462-  523 (87.17/51.76)	SLQYGDHRPYaaaCILQEWRR..KAGERAIRHEAEAPDQFiQDqVFDWLDGSSDAADPVNLPAV
  524-  585 (89.63/46.01)	SLLFGQLVKQglfCYQQYVQRliARGEAGLSFSQEGYSRH.RD.FLRWTCLHTADASVIRQRKV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.14|      12|      18|     743|     754|      14
---------------------------------------------------------------------------
  743-  754 (24.26/18.42)	QYWRGRGIHSRQ
  761-  772 (20.88/14.58)	QVDKGRYLEQAQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.06|      17|      18|    1472|    1489|      15
---------------------------------------------------------------------------
 1472- 1489 (23.46/23.47)	DLSSESVFARDwREARVA
 1492- 1508 (29.60/21.36)	DEGSRSRSVTD.HEDGVA
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07338 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ATTSTAKRRLDDDEVQIVEGPARTSKKPRGKVGSRTKGKKR
2) LNDEGSRSRSVTDHEDGVAPTGQYQGASRRGSPALSTRSGVARVSGSSSAGSRRQSPATSTTVGHPLSRLSVSTA
1579
1490
1619
1564










Molecular Recognition Features






MoRF SequenceStartStop




1) KKPRGKVGSRTKGKKR
1604
1619