<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07313

Description Uncharacterized protein (Fragment)
SequenceMQKARAVPHLDEVVSLSAECAAIVHRGMPARARPPSREMAGDRKDKAASIEPFKPHPPTWRPPIHEAASLGWPDYIPDHPERMENLMSAKTVKEGLTILPYSSQEASTSHGDNLEKLESDDALERLGQLMTQVMERREAAMGSPGQTTYKMPPRVTVPDMRRAKWLDALADPAIPLKDIAAKASQAGAATPDFYIPHGPKGSELFDLLYNKNVPIDRAVWFVRIVGYNDMAPLRKQPGYNPMSYSFDTAKEIIMWHKKQLGEISLPTARLQSTALKQVFKGVLLDVDNRIAWCSKFVYTIQLTREFYKESMIDHGTFLLWAALHIGHCNLAQLAIFARVVDEYAVELCAHRAFAKALVDNSLVKLKEIETSPGSEHLEGLQKLLRKFIQLAMIDVPEAFINPRKWPFMVEHVFDVIDAYVPLNPETKDEVKEQALVQLRRTAQEVHRRNSALLFHQERTEPKGRIGHCIIAIRNLNMLGANSNLATFKFFEDSENTYDDQLKLLLTWAVSRFQYGDHRPYAVASILRKWMDDAKLQAIRQKVKVKPAEMLQDRLFLWLHNYPAHSLQSDMPAIAILIGELIRRGVFSYARYVQELVARGELEGSPGEEPSRHVEVIRQTPLIKTWEAQELLHKTSLFDRQLHTTPEDSDMMSMQREIVTSLPELFASSSDPISAESNFPIVLSGSRYEQARVIHHWLLPRILNKYSMKNADHQQGTLSLGSYATLVQLLTDTKLYIALLEFNLMTLNIASWSEGDLTEQTELFTAVLDTFERNSSIWACMDANATIAQGLFLKIQKLRFQRRRCPPLLRFIRQLRFWRSLSKQEKTIVETDYSRYVKELDDHSTGPSTTPSVIPEIHDIIQSSAPHSPYAVAVAIWGRFRTLEDWPVIVWDNVMQGLRDFSLKDTTREERLACSKRLSLVLHQIDRRLLKGFDHFLRLWCGRSEGFKVLDMNASHWELLVPLLIKLCVFNAVACSTILECFVYPVWRHFAAISASSDSQTYRERHVPCLFQTAILVLCLLLQNKATAGDGAGLTPISLPQLQRLQTRRLCIYEGASFQALLDGVCYLVSLCTNPLLTPEVSTTLLRLKMSLLDDPLFKQQVSRDPLAIKRALSSSSVIQRTPDIEDRMEETLMYLMNAEELDNASHTNDAEGDIWKQNVADLDPWCCHRAAVKLQLTLRRLCRLARSESPEAPAYALKLDRDTTALFTHDWSSEELVYIAEMLDGICAKTTGELLSKAYEKITDSLRGTLSNLTAQSANVFNGMATNTVHLMLKITTPVAVMESSHPEIPTSILESFLQTVSNTWRAVFSRVSPYTTLQAMDSKPIDGTVYRDLMMLTTRLLHYALGMMEHPSPEWKRISETVISFVIQFANFYGTDGPLRDSILFSMLLDT
Length1392
PositionKinase
OrganismCalocera cornea HHB12733
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Dacrymycetes> Dacrymycetales> Dacrymycetaceae> Calocera.
Aromaticity0.08
Grand average of hydropathy-0.196
Instability index46.27
Isoelectric point6.56
Molecular weight158087.26
Publications
PubMed=26659563

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07313
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     283.83|     123|     458|     452|     660|       1
---------------------------------------------------------------------------
  317-  378 (61.74/ 8.01)	FLLWAALHIGHCNLAQLAIFARVVDEyaveLCAHRAFAKALVDNSLVKLKEIETSPG...SEHLE.....................................................................................................................................................................................................................................................................................................................................................................................................
  452-  525 (75.75/47.66)	........................................................................................................................................................................................................................................................................................................glqkllrkfiqlamidvpeafinprkwpfmvehvfdvidayvplnpetkdevkeqalvqlrrtaqevhrrnsaLLFHQ.ERTEPKGrIGHCiiairnLNMLGANSNlaTFKFFEDSENTYDDQLKLLLTWAVSR..........FQYGDHRPYAVASI
  554-  614 (67.58/120.17)	LFLWLHNYPAHSLQSDMPAIAILIGE....LIRRGVFSYARYVQELVARGELEGSPGeepSRHVE.....................................................................................................................................................................................................................................................................................................................................................................................................
  919-  994 (78.75/20.53)	.................................................................virqtpliktweaqellhktslfdrqlhttpedsdmmsmqreivtslpelfasssdpisaesnfpivlsgsryeqarvihhwllprilnkysmknadhqqgtlslgsyatlvqlltdtklyiallefnlmtlniaswsegdlteqtelftavldtfernssiwacmdanatiaqglflkiqklrfqrrrcppllrfirqlrfwrslskqektivetdysryvkelddhstgpsttpsvipeihdiiqssaphspyavavaiwgrfrtledwpvivwdnvmqglrdfslkdttreerlacskrlsLVLHQiDRRLLKG.FDHF......LRLWCGRSE..GFKVLDMNASHWELLVPLLIKLCVFNavacstilecFVYPVWRHFAAISA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.85|      27|     458|     620|     660|       2
---------------------------------------------------------------------------
  622-  648 (47.80/43.75)	IKTWEAQELLHKTSLFDRQLHTTPEDS
  748-  774 (46.05/15.37)	IASWSEGDLTEQTELFTAVLDTFERNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.59|      12|      25|      29|      40|       3
---------------------------------------------------------------------------
   29-   40 (23.72/12.34)	PARARPPSREMA
   57-   68 (24.87/13.31)	PPTWRPPIHEAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.65|      20|     116|      73|      92|       5
---------------------------------------------------------------------------
   73-   92 (40.78/25.65)	PD.YIPDHPERME..NLMSAKTV
  191-  213 (29.86/16.69)	PDfYIPHGPKGSElfDLLYNKNV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07313 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ERLGQLMTQVMERREAAMGSPGQTTYKMPPR
2) VHRGMPARARPPSREMAGDRKDKAASIEPFKPHPPTWRPPIHEAASLGWPDYIPDHPERMENLMSA
124
24
154
89










Molecular Recognition Features






MoRF SequenceStartStop




NANANA